Development Level

Tbio 189 | 10,625
Tchem 41 | 1,890
Tdark 28 | 7,003

IMPC Phenotype

preweaning lethality, complete... 7 | 633
short tibia 5 | 82
decreased grip strength 4 | 123
decreased lean body mass 4 | 195
decreased total body fat amoun... 4 | 186
abnormal behavior 3 | 226
abnormal coat-hair pigmentatio... 3 | 54
abnormal lens morphology 3 | 73
abnormal retina morphology 3 | 100
decreased body length 3 | 108
decreased bone mineral density 3 | 126
decreased heart weight 3 | 44
enlarged heart 3 | 111
impaired glucose tolerance 3 | 52
increased or absent threshold ... 3 | 128
preweaning lethality, incomple... 3 | 260
abnormal eye morphology 2 | 38
abnormal femur morphology 2 | 14
abnormal humerus morphology 2 | 11
abnormal kidney morphology 2 | 30
abnormal pelvic girdle bone mo... 2 | 11
abnormal retinal blood vessel ... 2 | 18
abnormal seminal vesicle morph... 2 | 47
abnormal tibia morphology 2 | 14
abnormal tooth morphology 2 | 24
cataract 2 | 26
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased circulating free fat... 2 | 39
decreased circulating glucose ... 2 | 121
decreased erythrocyte cell num... 2 | 43
decreased hemoglobin content 2 | 53
decreased leukocyte cell numbe... 2 | 54
decreased mean corpuscular hem... 2 | 19
decreased mean corpuscular vol... 2 | 50
impaired righting response 2 | 19
improved glucose tolerance 2 | 56
increased circulating alkaline... 2 | 119
persistence of hyaloid vascula... 2 | 22
polydactyly 2 | 22
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal cranium morphology 1 | 32
abnormal digit morphology 1 | 13
abnormal ear morphology 1 | 5
abnormal embryo size 1 | 112
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal joint morphology 1 | 14
abnormal lymph node morphology 1 | 3
abnormal optic disc morphology 1 | 10
abnormal retinal pigmentation 1 | 61
abnormal retinal vasculature m... 1 | 15
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
cardiovascular system phenotyp... 1 | 35
decreased CD11b-low dendritic ... 1 | 3
decreased CD4-positive, CD25-p... 1 | 24
decreased blood urea nitrogen ... 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased cervical vertebrae n... 1 | 12
decreased circulating serum al... 1 | 79
decreased eosinophil cell numb... 1 | 41
decreased hematocrit 1 | 25
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased rib number 1 | 59
decreased threshold for audito... 1 | 32
dilated heart left ventricle 1 | 10
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
hydrops fetalis 1 | 22
increased NK T cell number 1 | 11
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating potassiu... 1 | 31
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased mean corpuscular vol... 1 | 91
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
irregularly shaped pupil 1 | 7
mydriasis 1 | 9
narrow eye opening 1 | 15
oligodactyly 1 | 14
polycystic kidney 1 | 9
thrombocytopenia 1 | 46
thrombocytosis 1 | 23

Disease

ovarian cancer 140 | 8,491
psoriasis 126 | 6,685
glioblastoma 96 | 5,572
invasive ductal carcinoma 95 | 2,950
osteosarcoma 95 | 7,933
medulloblastoma, large-cell 94 | 6,234
pilocytic astrocytoma 92 | 3,086
pancreatic cancer 89 | 2,300
Breast cancer 86 | 3,098
Carcinoma 85 | 2,147
intraductal papillary-mucinous adenoma (IPMA) 82 | 2,956
lung cancer 82 | 4,473
atypical teratoid / rhabdoid tumor 80 | 4,369
lung adenocarcinoma 80 | 2,714
lung carcinoma 79 | 2,844
intraductal papillary-mucinous carcinoma (IPMC) 75 | 2,988
non-small cell lung cancer 75 | 2,798
primary pancreatic ductal adenocarcinoma 74 | 1,271
intraductal papillary-mucinous neoplasm (IPMN) 73 | 3,289
breast carcinoma 71 | 1,614
interstitial cystitis 71 | 2,299
ulcerative colitis 69 | 2,087
cystic fibrosis 68 | 1,670
malignant mesothelioma 67 | 3,163
posterior fossa group A ependymoma 66 | 1,511
ductal carcinoma in situ 65 | 1,745
pediatric high grade glioma 64 | 2,712
sonic hedgehog group medulloblastoma 63 | 1,482
pituitary cancer 58 | 1,972
Duchenne muscular dystrophy 56 | 602
oligodendroglioma 52 | 2,849
gastric carcinoma 51 | 832
Cancer 50 | 2,346
adrenocortical carcinoma 47 | 1,427
primitive neuroectodermal tumor 46 | 3,031
autosomal dominant Emery-Dreifuss muscular dystrophy 44 | 499
Atopic dermatitis 41 | 944
colon cancer 41 | 1,475
juvenile dermatomyositis 41 | 1,189
nasopharyngeal carcinoma 40 | 1,056
subependymal giant cell astrocytoma 38 | 2,287
fibroadenoma 37 | 557
Becker muscular dystrophy 33 | 187
ependymoma 33 | 2,514
diabetes mellitus 32 | 1,663
adult high grade glioma 31 | 2,148
astrocytic glioma 30 | 2,241
group 4 medulloblastoma 29 | 1,875
limb girdle muscular dystrophy 2A 29 | 156
cutaneous lupus erythematosus 28 | 1,056
astrocytoma 27 | 1,493
esophageal adenocarcinoma 26 | 737
interstitial lung disease 26 | 292
group 3 medulloblastoma 24 | 2,254
urothelial carcinoma 24 | 318
Spontaneous abortion 21 | 108
Osteoarthritis 20 | 96
Pick disease 20 | 1,893
atypical teratoid/rhabdoid tumor 20 | 1,095
primary Sjogren syndrome 20 | 788
posterior fossa group B ependymoma 19 | 1,530
Endometriosis 18 | 535
Myopia 18 | 99
active Crohn's disease 18 | 918
acute quadriplegic myopathy 18 | 1,157
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,795
Kidney disease 17 | 397
glioblastoma multiforme 17 | 347
tuberculosis 17 | 1,563
Osteoporosis 16 | 259
head and neck cancer and chronic obstructive pulmonary disease 16 | 237
inflammatory breast cancer 16 | 404
pterygium 16 | 74
Ehlers-Danlos syndrome 15 | 42
Rheumatoid Arthritis 15 | 1,170
periodontitis 15 | 269
Arthritis 14 | 248
Dentinogenesis imperfecta 14 | 24
dermatomyositis 14 | 966
Colorectal Neoplasms 13 | 217
Down syndrome 13 | 548
Glaucoma 13 | 135
active ulcerative colitis 13 | 477
non primary Sjogren syndrome sicca 13 | 840
non-inflammatory breast cancer 13 | 208
Atherosclerosis 12 | 275
Degenerative disc disease 12 | 28
Mammary Neoplasms 12 | 410
Neoplasm Invasiveness 12 | 127
non-small cell lung carcinoma 12 | 413
Obesity 11 | 616
Prostatic Neoplasms 11 | 471
Vascular disease 11 | 281
head and neck cancer 11 | 270
Heart disease 10 | 279
Hydrolethalus syndrome 10 | 128
Schizophrenia 10 | 503
acute myeloid leukemia 10 | 785
adrenocortical adenoma 10 | 134
facioscapulohumeral dystrophy 10 | 286

Tissue

Female tissues 255 | 18,646
Digestive Tract 254 | 18,472
Endocrine System 253 | 18,511
Urinary Tract 253 | 18,443
Nervous System 252 | 18,560
Skin and soft tissues 250 | 18,114
Liver and Pancreas 249 | 18,135
Male tissues 248 | 17,968
Cardiovascular System 246 | 17,957
Blood and immune system 245 | 17,994
Respiratory system 242 | 17,483

Target Family

Non-IDG 214 | 11,969
Enzyme 44 | 4,146

UniProt Keyword

Extracellular matrix 258 | 258
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine-threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene Wnt-1 WNT1 Tbio Non-IDG -2.73870 492.7 294
Leucine-rich repeat transmembrane protein FLRT2 FLRT2 Tbio Non-IDG -1.05975 10.9 48
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.73976 5495.0 809
EGF-containing fibulin-like extracellular matrix protein 1 EFEMP1 Tbio Non-IDG -2.12889 148.3 205
Collagen alpha-1(VIII) chain COL8A1 Tbio Non-IDG -1.25305 16.3 98
Collagen alpha-1(I) chain COL1A1 Tbio Non-IDG -2.94271 807.7 451
Collagen alpha-1(IV) chain COL4A1 Tchem Non-IDG -2.25341 170.3 323
Collagen alpha-1(III) chain COL3A1 Tchem Non-IDG -2.54818 328.8 384
Elastin ELN Tbio Non-IDG -3.33458 2025.2 244
Calreticulin CALR Tbio Non-IDG -3.16449 1423.9 650