Development Level

Tbio 51 | 11,445
Tchem 7 | 1,598
Tdark 7 | 6,588
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal embryo size 5 | 220
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
embryonic growth retardation 3 | 106
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
decreased total body fat amoun... 2 | 207
hyperactivity 2 | 148
increased bone mineral content 2 | 108
increased lean body mass 2 | 172
small testis 2 | 58
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal locomotor behavior 1 | 24
abnormal skin appearance 1 | 3
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
convulsive seizures 1 | 13
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
edema 1 | 59
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
increased blood urea nitrogen ... 1 | 48
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased large unstained cell... 1 | 5
increased mean corpuscular vol... 1 | 92
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28

Disease

Carcinoma 49 | 11,493
medulloblastoma, large-cell 41 | 6,241
glioblastoma 38 | 5,792
atypical teratoid / rhabdoid tumor 36 | 5,112
adult high grade glioma 31 | 3,801
ependymoma 31 | 4,679
ovarian cancer 30 | 8,520
osteosarcoma 29 | 7,950
Astrocytoma, Pilocytic 28 | 3,081
psoriasis 28 | 6,694
group 3 medulloblastoma 27 | 4,104
oligodendroglioma 25 | 2,850
primitive neuroectodermal tumor 25 | 3,035
astrocytic glioma 24 | 2,597
lung carcinoma 20 | 2,843
subependymal giant cell astrocytoma 17 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
Kidney cancer 14 | 2,613
Pick disease 14 | 1,894
pancreatic cancer 13 | 2,398
lung cancer 12 | 4,740
malignant mesothelioma 12 | 3,232
pituitary cancer 12 | 1,972
Schizophrenia 10 | 1,160
lung adenocarcinoma 10 | 2,716
non-small cell lung cancer 10 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
invasive ductal carcinoma 9 | 2,951
Breast cancer 8 | 3,578
active ulcerative colitis 8 | 764
diabetes mellitus 8 | 1,728
primary pancreatic ductal adenocarcinoma 8 | 1,109
tuberculosis 8 | 2,010
cystic fibrosis 7 | 1,696
ductal carcinoma in situ 6 | 1,745
group 4 medulloblastoma 6 | 1,855
interstitial cystitis 6 | 2,312
progressive supranuclear palsy 6 | 676
Multiple myeloma 5 | 1,332
astrocytoma 5 | 1,146
colon cancer 5 | 1,478
Alzheimer's disease 4 | 658
Autistic Disorder 4 | 364
Bipolar Disorder 4 | 666
Cancer 4 | 2,499
Epilepsy 4 | 792
Griscelli syndrome type 2 4 | 12
Hemophagocytic lymphohistiocytosis 4 | 30
Retinitis pigmentosa 24 4 | 15
fibroadenoma 4 | 559
juvenile dermatomyositis 4 | 1,187
medulloblastoma 4 | 720
non primary Sjogren syndrome sicca 4 | 891
Autosomal recessive predisposition 3 | 1,442
Breast Neoplasms 3 | 445
Depressive disorder 3 | 409
Griscelli syndrome 3 | 24
Hermansky-Pudlak syndrome 3 | 42
Liver Cirrhosis, Experimental 3 | 769
Liver cancer 3 | 604
Obesity 3 | 678
Parkinson's disease 3 | 392
active Crohn's disease 3 | 922
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
breast carcinoma 3 | 1,638
ulcerative colitis 3 | 1,819
Cerebrovascular disease 2 | 238
Coronary artery disease 2 | 268
Diarrhea 2 | 253
Heart disease 2 | 306
Huntington's disease 2 | 76
Infantile onset 2 | 238
Kidney Failure 2 | 111
Melanoma 2 | 711
Mental Depression 2 | 333
Muscle Spasticity 2 | 195
Myopathy 2 | 185
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Pancytopenia 2 | 45
Psychotic Disorders 2 | 151
Seizures 2 | 596
Skeletal muscle atrophy 2 | 139
Skin cancer 2 | 469
Vascular disease 2 | 319
acute myeloid leukemia 2 | 783
cutaneous lupus erythematosus 2 | 1,057
gastric carcinoma 2 | 807
mucosa-associated lymphoid tissue lymphoma 2 | 484
muscle degeneration 2 | 139
nasopharyngeal carcinoma 2 | 1,058
nephrosclerosis 2 | 333
pancreatic carcinoma 2 | 562
spina bifida 2 | 1,074
substance-related disorder 2 | 162
urothelial carcinoma 2 | 318

Tissue

Endocrine System 67 | 18,159
Male tissues 67 | 17,142
Skin and soft tissues 67 | 17,230
Digestive Tract 66 | 17,369
Nervous System 66 | 16,725
Female tissues 65 | 17,400
Liver and Pancreas 65 | 16,750
Respiratory system 65 | 16,393
Urinary Tract 65 | 16,678
Blood and immune system 63 | 16,909
Cardiovascular System 60 | 15,192

Target Family

Non-IDG 51 | 12,091
Enzyme 9 | 4,145
Kinase 5 | 634
Ion Channel 1 | 344
Transporter 1 | 473

UniProt Keyword

Exocytosis 67 | 67
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium-dependent secretion activator 2 CADPS2 Tbio Non-IDG -1.18033 15.0 36
Regulating synaptic membrane exocytosis protein 3 RIMS3 Tbio Non-IDG -1.28577 18.9 75
Exocyst complex component 3-like protein EXOC3L1 Tdark Non-IDG 0.10 1.30 62
Ras-related protein Rab-3D RAB3D Tbio Enzyme -2.56190 342.2 106
Protein unc-13 homolog D UNC13D Tbio Non-IDG -1.93790 85.1 158
Syntaxin-binding protein 5-like STXBP5L Tbio Non-IDG -0.71494 6.16 5
Potassium voltage-gated channel subfamily B member 1 KCNB1 Tclin Ion Channel -2.57484 386.0 303
Serine/threonine-protein kinase BRSK2 BRSK2 Tchem Kinase -1.92813 85.3 187
Solute carrier family 17 member 9 SLC17A9 Tchem Transporter -1.56271 40.4 11
Rap guanine nucleotide exchange factor 4 RAPGEF4 Tchem Non-IDG -2.46995 289.7 118