Development Level

Tbio 77 | 10,625
Tclin 29 | 602
Tchem 17 | 1,890
Tdark 3 | 7,003

Collection

Ion Channel: IDG Consortium (Targets) 3 | 102
Kinase: IDG Consortium (Complete/Control) 1 | 37

IMPC Phenotype

preweaning lethality, complete... 10 | 633
decreased bone mineral content 4 | 157
decreased lean body mass 4 | 195
decreased total body fat amoun... 4 | 186
abnormal behavior 3 | 226
abnormal gait 3 | 51
decreased body length 3 | 108
decreased bone mineral density 3 | 126
improved glucose tolerance 3 | 56
increased bone mineral content 3 | 92
abnormal retina morphology 2 | 100
abnormal retinal pigmentation 2 | 61
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
enlarged heart 2 | 111
hyperactivity 2 | 108
increased blood urea nitrogen ... 2 | 44
increased circulating creatini... 2 | 29
increased lean body mass 2 | 107
increased leukocyte cell numbe... 2 | 37
preweaning lethality, incomple... 2 | 260
short tibia 2 | 82
abnormal bone structure 1 | 131
abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal placement of pupils 1 | 4
abnormal retinal vasculature m... 1 | 15
abnormal sensory capabilities-... 1 | 3
abnormal skin morphology 1 | 23
absent vibrissae 1 | 14
decreased CD8-positive, alpha-... 1 | 26
decreased NK T cell number 1 | 28
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased granulocyte number 1 | 8
decreased heart rate 1 | 10
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean platelet volume 1 | 12
decreased prepulse inhibition 1 | 52
decreased red blood cell distr... 1 | 11
decreased respiratory quotient 1 | 12
decreased rib number 1 | 59
decreased startle reflex 1 | 48
enlarged kidney 1 | 7
enlarged lymph nodes 1 | 27
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased B cell number 1 | 23
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased effector memory CD8-... 1 | 14
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
male infertility 1 | 62
microphthalmia 1 | 15
prenatal lethality prior to he... 1 | 64
thrombocytosis 1 | 23

Disease

Epilepsy 126 | 346
glioblastoma 71 | 5,572
medulloblastoma, large-cell 68 | 6,234
osteosarcoma 63 | 7,933
ovarian cancer 61 | 8,491
atypical teratoid / rhabdoid tumor 57 | 4,369
psoriasis 53 | 6,685
Intellectual disability 48 | 573
pilocytic astrocytoma 47 | 3,086
primitive neuroectodermal tumor 45 | 3,031
oligodendroglioma 44 | 2,849
pediatric high grade glioma 37 | 2,712
ependymoma 36 | 2,514
Carcinoma 35 | 2,147
Pick disease 35 | 1,893
lung cancer 35 | 4,473
subependymal giant cell astrocytoma 35 | 2,287
astrocytic glioma 33 | 2,241
lung carcinoma 33 | 2,844
malignant mesothelioma 30 | 3,163
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,956
adult high grade glioma 25 | 2,148
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,289
invasive ductal carcinoma 25 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,988
sonic hedgehog group medulloblastoma 22 | 1,482
Autistic Disorder 20 | 320
astrocytoma 20 | 1,493
lung adenocarcinoma 20 | 2,714
Breast cancer 19 | 3,098
Neurodegenerative disease 19 | 383
group 4 medulloblastoma 19 | 1,875
pituitary cancer 19 | 1,972
posterior fossa group A ependymoma 19 | 1,511
Schizophrenia 18 | 503
medulloblastoma 18 | 1,524
non-small cell lung cancer 18 | 2,798
colon cancer 17 | 1,475
group 3 medulloblastoma 17 | 2,254
posterior fossa group B ependymoma 17 | 1,530
Cancer 15 | 2,346
Early infantile epileptic encephalopathy with suppression bursts 15 | 18
interstitial cystitis 15 | 2,299
ductal carcinoma in situ 14 | 1,745
Alzheimer's disease 13 | 644
Lennox-Gastaut syndrome 12 | 34
Parkinson's disease 12 | 364
Status Epilepticus 12 | 85
tuberculosis 12 | 1,563
ulcerative colitis 12 | 2,087
Seizures 11 | 95
atypical teratoid/rhabdoid tumor 11 | 1,095
breast carcinoma 11 | 1,614
primary pancreatic ductal adenocarcinoma 11 | 1,271
Local anesthesia 10 | 40
Microcephaly 10 | 149
Multiple Sclerosis 10 | 498
West Syndrome 10 | 24
diabetes mellitus 10 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
Simple partial seizure 9 | 26
cystic fibrosis 9 | 1,670
pancreatic cancer 9 | 2,300
Epileptic Encephalopathy, Early Infantile, 6 8 | 8
Obesity 8 | 616
Osteoporosis 8 | 259
Tonic-clonic epilepsy 8 | 47
acute quadriplegic myopathy 8 | 1,157
progressive supranuclear palsy 8 | 674
Eaton-Lambert syndrome 7 | 40
Epilepsy characterized by intractable complex partial seizures 7 | 28
Partial Epilepsy Treatment Adjunct 7 | 16
Rheumatoid Arthritis 7 | 1,170
Spasticity 7 | 26
acute myeloid leukemia 7 | 785
juvenile dermatomyositis 7 | 1,189
nasopharyngeal carcinoma 7 | 1,056
non primary Sjogren syndrome sicca 7 | 840
Bipolar disorder in remission 6 | 19
Cerebrovascular disease 6 | 231
Child Development Disorders, Pervasive 6 | 55
Dystonia 6 | 77
Dysuria 6 | 24
Epilepsy, Myoclonic Juvenile 6 | 6
General anesthesia 6 | 53
Localization-related epilepsy 6 | 13
Long QT syndrome 6 | 53
Multiple myeloma 6 | 1,327
Myoclonic Epilepsy, Juvenile 6 | 7
PITT-HOPKINS SYNDROME 6 | 21
Tonic-clonic seizure 6 | 11
Urinary Tract Irritation 6 | 24
adrenocortical carcinoma 6 | 1,427
tuberculosis and treatment for 6 months 6 | 686
Attention deficit hyperactivity disorder 5 | 156
Vascular disease 5 | 281
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
chronic rhinosinusitis 5 | 512
dermatomyositis 5 | 966
spina bifida 5 | 1,064

Tissue

Digestive Tract 126 | 18,472
Liver and Pancreas 126 | 18,135
Male tissues 126 | 17,968
Nervous System 126 | 18,560
Cardiovascular System 125 | 17,957
Endocrine System 125 | 18,511
Female tissues 125 | 18,646
Skin and soft tissues 125 | 18,114
Urinary Tract 125 | 18,443
Blood and immune system 124 | 17,994
Respiratory system 123 | 17,483

Target Family

Non-IDG 46 | 11,969
Enzyme 29 | 4,146
Ion Channel 29 | 341
Transporter 9 | 473
Kinase 4 | 634
Transcription Factor 4 | 1,400
Epigenetic 2 | 242
GPCR 2 | 408
TF/Epigenetic 1 | 38

UniProt Keyword

Epilepsy 126 | 126
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine-threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.85874 681.4 264
Pyridoxine-5'-phosphate oxidase PNPO Tchem Enzyme -1.92404 83.6 160
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.53667 324.2 196
Vacuolar protein sorting-associated protein 53 homolog VPS53 Tbio Non-IDG -0.76155 5.77 94
TBC1 domain family member 24 TBC1D24 Tbio Non-IDG -2.22045 137.3 20
Ceramide synthase 1 CERS1 Tbio Enzyme -1.57090 34.6 153
WW domain-containing oxidoreductase WWOX Tbio Enzyme -3.56179 2916.0 232
Mitogen-activated protein kinase 10 MAPK10 Tchem Kinase -2.27384 181.6 339
Calcium-activated potassium channel subunit alpha-1 KCNMA1 Tclin Ion Channel -3.08349 1170.6 213
Lactosylceramide alpha-2,3-sialyltransferase ST3GAL5 Tbio Enzyme -1.79569 62.9 97