Development Level

Tbio 175 | 11,651
Tdark 31 | 6,593
Tchem 22 | 1,388
Tclin 6 | 612

Collection

GPCR: IDG Consortium (Targets) 3 | 126
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

preweaning lethality, complete... 10 | 979
decreased vertical activity 7 | 208
enlarged heart 5 | 210
preweaning lethality, incomple... 5 | 499
abnormal snout morphology 4 | 23
cardiovascular system phenotyp... 4 | 36
decreased body weight 4 | 161
decreased total body fat amoun... 4 | 207
embryonic lethality prior to t... 4 | 278
increased lean body mass 4 | 172
increased total body fat amoun... 4 | 134
abnormal heart morphology 3 | 162
decreased bone mineral content 3 | 151
decreased lean body mass 3 | 135
decreased prepulse inhibition 3 | 82
increased blood urea nitrogen ... 3 | 48
increased bone mineral content 3 | 108
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal eye morphology 2 | 68
abnormal locomotor behavior 2 | 24
abnormal pericardium morpholog... 2 | 26
abnormal seminal vesicle morph... 2 | 114
abnormal tooth morphology 2 | 24
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating total pr... 2 | 49
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
decreased startle reflex 2 | 75
embryonic lethality prior to o... 2 | 239
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased circulating iron lev... 2 | 30
increased hematocrit 2 | 46
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
abnormal coat appearance 1 | 31
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased heart rate variabili... 1 | 13
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased pulmonary respirator... 1 | 5
decreased red blood cell distr... 1 | 41
edema 1 | 59
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
enlarged stomach 1 | 2
female infertility 1 | 60
hydroencephaly 1 | 14
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
limb grasping 1 | 41
long tibia 1 | 25
shortened RR interval 1 | 17
small testis 1 | 58
small thymus 1 | 16
tremors 1 | 39

Disease

Carcinoma 200 | 11,493
psoriasis 118 | 6,694
glioblastoma 101 | 5,792
ovarian cancer 95 | 8,520
Kidney cancer 90 | 2,613
Breast cancer 89 | 3,578
lung cancer 87 | 4,740
medulloblastoma, large-cell 85 | 6,241
ependymoma 84 | 4,679
lung carcinoma 83 | 2,843
osteosarcoma 83 | 7,950
atypical teratoid / rhabdoid tumor 80 | 5,112
lung adenocarcinoma 75 | 2,716
invasive ductal carcinoma 74 | 2,951
Astrocytoma, Pilocytic 71 | 3,081
non-small cell lung cancer 68 | 2,890
interstitial cystitis 66 | 2,312
group 3 medulloblastoma 65 | 4,104
adult high grade glioma 63 | 3,801
pancreatic cancer 62 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 58 | 2,955
Cancer 57 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 57 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 57 | 3,291
malignant mesothelioma 56 | 3,232
oligodendroglioma 55 | 2,850
pituitary cancer 52 | 1,972
cystic fibrosis 45 | 1,696
Melanoma 43 | 711
astrocytic glioma 43 | 2,597
breast carcinoma 42 | 1,638
Liver cancer 41 | 604
Skin cancer 40 | 469
ductal carcinoma in situ 40 | 1,745
subependymal giant cell astrocytoma 40 | 2,287
colon cancer 39 | 1,478
primitive neuroectodermal tumor 39 | 3,035
ulcerative colitis 38 | 1,819
Autosomal recessive predisposition 37 | 1,442
adrenocortical carcinoma 36 | 1,428
Schizophrenia 33 | 1,160
pancreatic ductal adenocarcinoma liver metastasis 33 | 1,962
primary pancreatic ductal adenocarcinoma 32 | 1,109
cutaneous lupus erythematosus 31 | 1,057
diabetes mellitus 31 | 1,728
Atopic dermatitis 30 | 952
group 4 medulloblastoma 29 | 1,855
gastric carcinoma 28 | 807
Endometrial cancer 26 | 311
Pick disease 25 | 1,894
pediatric high grade glioma 24 | 1,064
Duchenne muscular dystrophy 22 | 601
astrocytoma 21 | 1,146
Vascular disease 19 | 319
juvenile dermatomyositis 19 | 1,187
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 510
mucosa-associated lymphoid tissue lymphoma 18 | 484
tuberculosis 18 | 2,010
nasopharyngeal carcinoma 17 | 1,058
Alzheimer's disease 16 | 658
Bipolar Disorder 16 | 666
fibroadenoma 16 | 559
Breast Neoplasms 15 | 445
Kidney disease 15 | 430
Liver Cirrhosis, Experimental 15 | 769
Mammary Neoplasms 15 | 425
Intellectual disability 14 | 1,016
Rheumatoid arthritis 14 | 1,191
Short stature 14 | 531
dermatomyositis 14 | 966
esophageal adenocarcinoma 14 | 737
primary Sjogren syndrome 14 | 735
Asthma 13 | 385
Hypertension 13 | 396
sonic hedgehog group medulloblastoma 13 | 467
Large intestine cancer 12 | 126
Obesity 12 | 678
Orbital separation excessive 12 | 244
non primary Sjogren syndrome sicca 12 | 891
pancreatic carcinoma 12 | 562
Brachydactyly 11 | 156
Cerebrovascular disease 11 | 238
Coronary artery disease 11 | 268
Endometriosis 11 | 540
Multiple Sclerosis 11 | 540
Muscle hypotonia 11 | 571
active ulcerative colitis 11 | 764
spina bifida 11 | 1,074
Atherosclerosis 10 | 291
Autistic Disorder 10 | 364
Cataract 10 | 297
Epilepsy 10 | 792
Heart disease 10 | 306
Lens Opacities 10 | 231
Osteoarthritis 10 | 184
active Crohn's disease 10 | 922
acute quadriplegic myopathy 10 | 1,158
nephrosclerosis 10 | 333
posterior fossa group A ependymoma 10 | 468
urothelial carcinoma 10 | 318

Tissue

Endocrine System 222 | 18,159
Digestive Tract 215 | 17,369
Female tissues 213 | 17,400
Male tissues 213 | 17,142
Skin and soft tissues 211 | 17,230
Urinary Tract 211 | 16,678
Nervous System 209 | 16,725
Liver and Pancreas 208 | 16,750
Blood and immune system 205 | 16,909
Respiratory system 199 | 16,393
Cardiovascular System 177 | 15,192

Target Family

Non-IDG 183 | 12,091
Enzyme 40 | 4,145
GPCR 9 | 408
Kinase 2 | 634

UniProt Keyword

EGF-like domain 234 | 234
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Contactin-associated protein-like 4 CNTNAP4 Tbio Non-IDG -0.73408 0.00000 148
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Cysteine-rich with EGF-like domain protein 2 CRELD2 Tbio Non-IDG -0.79330 8.01 176
Inactive serine protease PAMR1 PAMR1 Tdark Enzyme -0.86262 5.98 22
Collagen and calcium-binding EGF domain-containing protein 1 CCBE1 Tbio Non-IDG -1.27652 20.3 165
Nephronectin NPNT Tbio Non-IDG -1.54450 37.2 104
C-type lectin domain family 18 member B CLEC18B Tdark Non-IDG 0.35 0.31 6
Disintegrin and metalloproteinase domain-containing protein 21 ADAM21 Tdark Enzyme -0.76419 6.37 28
Tolloid-like protein 2 TLL2 Tbio Non-IDG -1.00652 6.10 35
E-selectin SELE Tchem Non-IDG -3.44926 2672.1 919