Development Level

Tbio 20 | 11,445
Tclin 7 | 613
Tchem 4 | 1,598

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
hyperactivity 2 | 148
increased circulating sodium l... 2 | 71
preweaning lethality, complete... 2 | 979
abnormal gait 1 | 69
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased neutrophil cell numb... 1 | 42
increased circulating LDL chol... 1 | 13
increased circulating alanine ... 1 | 13
increased circulating chloride... 1 | 41
increased circulating triglyce... 1 | 42
male infertility 1 | 123

Disease

Dystonia 31 | 164
Carcinoma 21 | 11,493
osteosarcoma 16 | 7,950
ovarian cancer 13 | 8,520
psoriasis 13 | 6,694
atypical teratoid / rhabdoid tumor 12 | 5,112
ependymoma 12 | 4,679
glioblastoma 12 | 5,792
medulloblastoma, large-cell 12 | 6,241
Torticollis 11 | 18
Tremor 11 | 113
Autosomal recessive predisposition 10 | 1,442
Bipolar Disorder 10 | 666
Cervical Dystonia 10 | 26
Dysarthria 10 | 192
Intellectual disability 10 | 1,016
Parkinson's disease 10 | 392
Spasmodic torticollis 10 | 17
oligodendroglioma 10 | 2,850
Depressive disorder 9 | 409
Dystonic disease 9 | 106
Schizophrenia 9 | 1,160
group 3 medulloblastoma 9 | 4,104
Astrocytoma, Pilocytic 8 | 3,081
Breast cancer 8 | 3,578
Cognitive delay 8 | 608
Deglutition Disorders 8 | 132
Epilepsy 8 | 792
Global developmental delay 8 | 608
Mental and motor retardation 8 | 608
Choreatic disease 7 | 52
Infantile onset 7 | 238
Parkinsonian Disorders 7 | 56
adult high grade glioma 7 | 3,801
diabetes mellitus 7 | 1,728
malignant mesothelioma 7 | 3,232
primitive neuroectodermal tumor 7 | 3,035
Deafness dystonia syndrome 6 | 21
Dystonia, Limb 6 | 9
Highly variable severity 6 | 157
Optic Atrophy 6 | 242
Organic writer's cramp 6 | 10
Pick disease 6 | 1,894
Variable expressivity 6 | 157
ductal carcinoma in situ 6 | 1,745
group 4 medulloblastoma 6 | 1,855
invasive ductal carcinoma 6 | 2,951
lung cancer 6 | 4,740
lung carcinoma 6 | 2,843
pancreatic cancer 6 | 2,398
Attention deficit hyperactivity disorder 5 | 278
Bradykinesia 5 | 34
Cerebellar Ataxia 5 | 304
Dull intelligence 5 | 645
Hyperactive behavior 5 | 91
Hyperreflexia 5 | 209
Kidney cancer 5 | 2,613
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Muscle Rigidity 5 | 49
Poor school performance 5 | 645
Progressive disorder 5 | 142
Seizures 5 | 596
Static Tremor 5 | 21
astrocytic glioma 5 | 2,597
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
Acquired scoliosis 4 | 281
Anxiety 4 | 136
Anxiety disease 4 | 113
Blepharoptosis 4 | 231
Cachexia 4 | 50
Cerebral atrophy 4 | 178
Childhood onset 4 | 38
Creatine phosphokinase serum increased 4 | 110
Curvature of spine 4 | 282
Dystonia Disorders 4 | 6
Dystonia Musculorum Deformans 4 | 5
Elevated creatine kinase 4 | 110
Gait Ataxia 4 | 51
Mental Depression 4 | 333
Mental deterioration 4 | 32
Migraine 4 | 83
Mood Disorders 4 | 184
Neurodegenerative disease 4 | 414
Obesity 4 | 678
Osteoarthritis 4 | 184
Sensorineural Hearing Loss (disorder) 4 | 284
Short stature 4 | 531
Small head 4 | 374
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
non primary Sjogren syndrome sicca 4 | 891
non-small cell lung cancer 4 | 2,890
ulcerative colitis 4 | 1,819

Tissue

Endocrine System 31 | 18,159
Digestive Tract 30 | 17,369
Female tissues 30 | 17,400
Nervous System 30 | 16,725
Liver and Pancreas 29 | 16,750
Male tissues 29 | 17,142
Skin and soft tissues 28 | 17,230
Blood and immune system 27 | 16,909
Urinary Tract 27 | 16,678
Respiratory system 26 | 16,393
Cardiovascular System 25 | 15,192

Target Family

Non-IDG 12 | 12,091
Enzyme 9 | 4,145
Transporter 5 | 473
Kinase 2 | 634
GPCR 1 | 408
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

UniProt Keyword

Dystonia 31 | 31
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tubulin beta-4A chain TUBB4A Tclin Non-IDG -2.98371 896.1 90
GTP cyclohydrolase 1 GCH1 Tbio Enzyme -2.80099 639.3 247
Anoctamin-3 ANO3 Tbio Non-IDG -1.18072 15.2 79
Epsilon-sarcoglycan SGCE Tbio Non-IDG -2.19042 158.3 93
Collagen alpha-3(VI) chain COL6A3 Tbio Non-IDG -1.79687 61.3 32
Cip1-interacting zinc finger protein CIZ1 Tbio Non-IDG -1.41253 31.2 75
Sodium-dependent dopamine transporter SLC6A3 Tclin Transporter -3.59848 3752.4 324
Sepiapterin reductase SPR Tbio Enzyme -1.58814 36.9 174
Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B Tclin Ion Channel -2.24422 170.7 75
NADH-ubiquinone oxidoreductase chain 4 MT-ND4 Tclin Enzyme -3.03991 1074.3 9