Development Level

Tbio 1,913 | 11,178
Tdark 887 | 6,569
Tchem 515 | 1,885
Tclin 284 | 612

Collection

GPCR: IDG Consortium (Targets) 53 | 126
Ion Channel: IDG Consortium (T... 30 | 99
GPCR: IDG Consortium (Complete... 17 | 25
Kinase: IDG Consortium (Target... 2 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 75 | 979
preweaning lethality, incomple... 73 | 499
decreased vertical activity 59 | 208
enlarged heart 59 | 210
abnormal heart morphology 45 | 162
abnormal behavior 40 | 298
decreased total body fat amoun... 35 | 207
abnormal seminal vesicle morph... 33 | 114
abnormal bone structure 28 | 187
increased lean body mass 26 | 172
decreased bone mineral content 24 | 151
embryonic lethality prior to t... 24 | 278
small superior vagus ganglion 23 | 74
hypoactivity 22 | 132
decreased body weight 20 | 161
decreased circulating glucose ... 20 | 126
increased bone mineral content 20 | 108
abnormal kidney morphology 19 | 65
increased total body fat amoun... 19 | 134
abnormal embryo size 18 | 220
decreased bone mineral density 18 | 126
decreased lean body mass 18 | 135
short tibia 18 | 97
decreased grip strength 17 | 116
hyperactivity 17 | 148
abnormal eye morphology 16 | 68
cataract 15 | 92
hydrometra 15 | 53
improved glucose tolerance 15 | 79
increased mean corpuscular vol... 15 | 92
abnormal gait 14 | 69
abnormal sleep behavior 14 | 70
decreased circulating insulin ... 14 | 76
decreased circulating serum al... 14 | 82
decreased circulating choleste... 13 | 93
embryonic lethality prior to o... 13 | 239
increased circulating sodium l... 13 | 71
decreased body length 12 | 101
decreased leukocyte cell numbe... 12 | 73
decreased mean corpuscular vol... 12 | 79
increased leukocyte cell numbe... 12 | 47
increased mean corpuscular hem... 12 | 96
abnormal skin morphology 11 | 50
decreased circulating triglyce... 11 | 79
decreased fasted circulating g... 11 | 65
decreased lymphocyte cell numb... 11 | 83
decreased neutrophil cell numb... 11 | 42
decreased startle reflex 11 | 75
impaired glucose tolerance 11 | 75
increased blood urea nitrogen ... 11 | 48
increased circulating alkaline... 11 | 122
male infertility 11 | 123
abnormal epididymis morphology 10 | 42
abnormal testis morphology 10 | 43
abnormal vibrissa morphology 10 | 25
decreased erythrocyte cell num... 10 | 62
decreased heart weight 10 | 27
embryonic growth retardation 10 | 106
enlarged spleen 10 | 41
female infertility 10 | 60
increased circulating choleste... 10 | 66
increased circulating triglyce... 10 | 42
increased fasted circulating g... 10 | 76
increased heart weight 10 | 62
increased hemoglobin content 10 | 45
increased monocyte cell number 10 | 63
increased or absent threshold ... 10 | 101
increased startle reflex 10 | 112
prolonged ST segment 10 | 36
small testis 10 | 58
abnormal coat-hair pigmentatio... 9 | 64
abnormal spleen morphology 9 | 55
cardiovascular system phenotyp... 9 | 36
decreased circulating HDL chol... 9 | 68
decreased circulating creatini... 9 | 39
decreased circulating total pr... 9 | 49
increased circulating HDL chol... 9 | 80
increased circulating chloride... 9 | 41
increased lymphocyte cell numb... 9 | 32
prolonged QT interval 9 | 38
thrombocytopenia 9 | 56
decreased blood urea nitrogen ... 8 | 51
decreased prepulse inhibition 8 | 82
increased circulating iron lev... 8 | 30
increased hematocrit 8 | 46
tremors 8 | 39
abnormal lens morphology 7 | 81
decreased T cell number 7 | 15
decreased eosinophil cell numb... 7 | 24
decreased hemoglobin content 7 | 68
decreased mean corpuscular hem... 7 | 31
increased bone mineral density 7 | 72
increased mean platelet volume 7 | 45
pallor 7 | 34
decreased circulating alkaline... 6 | 46
decreased circulating free fat... 6 | 31
increased circulating potassiu... 6 | 29
pale yolk sac 6 | 25
prenatal lethality prior to he... 6 | 87
thrombocytosis 6 | 27

Disease

Carcinoma 2,030 | 11,192
psoriasis 1,300 | 6,514
ovarian cancer 1,128 | 8,297
osteosarcoma 1,092 | 7,766
glioblastoma 904 | 5,635
lung cancer 898 | 4,607
medulloblastoma, large-cell 894 | 6,086
lung carcinoma 733 | 2,755
Cancer 710 | 2,388
atypical teratoid / rhabdoid tumor 710 | 4,971
ependymoma 706 | 4,559
Breast cancer 649 | 3,469
adult high grade glioma 645 | 3,701
interstitial cystitis 643 | 2,237
Astrocytoma, Pilocytic 634 | 3,006
lung adenocarcinoma 630 | 2,627
invasive ductal carcinoma 619 | 2,867
non-small cell lung cancer 610 | 2,799
malignant mesothelioma 582 | 3,135
intraductal papillary-mucinous adenoma (IPMA) 578 | 2,872
intraductal papillary-mucinous neoplasm (IPMN) 553 | 3,204
intraductal papillary-mucinous carcinoma (IPMC) 540 | 2,902
pancreatic cancer 539 | 2,322
group 3 medulloblastoma 528 | 4,002
Kidney cancer 501 | 2,548
diabetes mellitus 492 | 1,683
ulcerative colitis 467 | 1,765
tuberculosis 449 | 1,963
cystic fibrosis 433 | 1,629
oligodendroglioma 430 | 2,768
pituitary cancer 407 | 1,915
primitive neuroectodermal tumor 378 | 2,957
subependymal giant cell astrocytoma 373 | 2,230
breast carcinoma 369 | 1,589
Autosomal recessive predisposition 365 | 1,407
ductal carcinoma in situ 360 | 1,686
astrocytic glioma 346 | 2,530
Schizophrenia 345 | 1,136
colon cancer 321 | 1,428
cutaneous lupus erythematosus 317 | 1,016
pancreatic ductal adenocarcinoma liver metastasis 314 | 1,911
Rheumatoid arthritis 282 | 1,156
adrenocortical carcinoma 276 | 1,385
group 4 medulloblastoma 263 | 1,806
primary pancreatic ductal adenocarcinoma 238 | 1,071
Atopic dermatitis 237 | 915
Melanoma 222 | 689
Pick disease 208 | 1,856
Bipolar Disorder 206 | 646
gastric carcinoma 198 | 781
Kidney disease 195 | 411
Liver Cirrhosis, Experimental 195 | 733
astrocytoma 193 | 1,113
Multiple Sclerosis 192 | 527
active Crohn's disease 192 | 882
juvenile dermatomyositis 191 | 1,147
nasopharyngeal carcinoma 189 | 1,024
Arthritis 182 | 276
Duchenne muscular dystrophy 182 | 587
primary Sjogren syndrome 179 | 710
Hypersensitivity reaction type II disease 176 | 245
Asthma 174 | 370
Obesity 174 | 655
esophageal adenocarcinoma 170 | 696
Epilepsy 169 | 775
pediatric high grade glioma 169 | 1,035
Skin cancer 167 | 451
active ulcerative colitis 163 | 736
dermatomyositis 158 | 941
mucosa-associated lymphoid tissue lymphoma 158 | 473
Liver cancer 151 | 589
Atherosclerosis 148 | 276
Hypertension 146 | 372
fibroadenoma 143 | 538
Alzheimer's disease 142 | 640
Depressive disorder 142 | 401
acute quadriplegic myopathy 139 | 1,133
Multiple myeloma 137 | 1,296
Anemia 134 | 353
autosomal dominant Emery-Dreifuss muscular dystrophy 133 | 492
non primary Sjogren syndrome sicca 133 | 861
Intellectual disability 131 | 998
Coronary artery disease 130 | 253
Autistic Disorder 129 | 358
spina bifida 126 | 1,053
Seizures 121 | 584
Endometriosis 119 | 521
periodontitis 115 | 280
Liver disease 114 | 227
Human immunodeficiency virus infectious disease 113 | 136
Prostatic Neoplasms 112 | 472
medulloblastoma 112 | 702
Alcoholic Intoxication, Chronic 111 | 283
Down syndrome 109 | 480
Major Depressive Disorder 109 | 293
Mental Depression 109 | 325
Cerebrovascular disease 108 | 223
Ankylosing spondylitis 107 | 134
Vascular disease 106 | 294
posterior fossa group A ependymoma 106 | 456

Tissue

Endocrine System 2,862 | 18,159
Female tissues 2,716 | 17,400
Digestive Tract 2,711 | 17,369
Skin and soft tissues 2,658 | 17,230
Male tissues 2,653 | 17,142
Blood and immune system 2,621 | 16,909
Urinary Tract 2,553 | 16,678
Liver and Pancreas 2,545 | 16,750
Nervous System 2,520 | 16,725
Respiratory system 2,459 | 16,393
Cardiovascular System 2,144 | 15,192

Target Family

Non-IDG 2,043 | 12,091
Enzyme 635 | 4,145
oGPCR 388 | 421
GPCR 284 | 408
Ion Channel 118 | 344
Kinase 71 | 634
Transporter 50 | 473
Transcription Factor 7 | 1,400
Epigenetic 2 | 242
Nuclear Receptor 1 | 48

UniProt Keyword

Disulfide bond 3,599 | 3,599
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-4 IL4 Tbio Non-IDG -3.98318 9219.0 1325
Beta-1,4-galactosyltransferase 7 B4GALT7 Tbio Enzyme -1.56894 38.8 65
Dystroglycan DAG1 Tbio Enzyme -2.77503 560.0 254
Nidogen-2 NID2 Tbio Non-IDG -1.62355 40.1 116
Kazal-type serine protease inhibitor domain-containing protein 1 KAZALD1 Tdark Enzyme -0.50068 4.33 42
Prostate-associated microseminoprotein MSMP Tdark Non-IDG -1.30530 20.7 5
Somatostatin receptor type 4 SSTR4 Tclin GPCR -1.72615 44.8 147
Immunoglobulin heavy variable 2-70D IGHV2-70D Tdark Non-IDG 0.00000 0
Immunoglobulin heavy variable 3-66 IGHV3-66 Tdark Non-IDG 0.00000 0
Immunoglobulin heavy variable 4-61 IGHV4-61 Tdark Non-IDG 0.00000 0