Development Level

Tbio 36 | 10,625
Tchem 32 | 1,890
Tdark 10 | 7,003
Tclin 4 | 602

IMPC Term

decreased circulating iron lev... 3 | 25
hyperactivity 3 | 108
increased B cell number 3 | 23
preweaning lethality, complete... 3 | 633
preweaning lethality, incomple... 3 | 260
abnormal behavior 2 | 226
decreased body weight 2 | 174
decreased grip strength 2 | 123
decreased lactate dehydrogenas... 2 | 14
increased or absent threshold ... 2 | 128
vertebral transformation 2 | 12
abnormal behavioral response t... 1 | 52
abnormal coat/ hair morphology 1 | 18
abnormal craniofacial morpholo... 1 | 12
abnormal femur morphology 1 | 14
abnormal forebrain morphology 1 | 4
abnormal glucose homeostasis 1 | 5
abnormal hindbrain morphology 1 | 2
abnormal iris pigmentation 1 | 3
abnormal limb position 1 | 3
abnormal lumbar vertebrae morp... 1 | 6
abnormal midbrain morphology 1 | 2
abnormal neural tube closure 1 | 37
abnormal response to tactile s... 1 | 16
abnormal seminal vesicle morph... 1 | 47
abnormal skin condition 1 | 6
abnormal thoracic vertebrae mo... 1 | 16
abnormal vocalization 1 | 21
decreased CD8-positive, alpha-... 1 | 26
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating insulin ... 1 | 75
decreased circulating total pr... 1 | 41
decreased fasted circulating g... 1 | 49
decreased granulocyte number 1 | 8
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased spleen weight 1 | 13
decreased thermal nociceptive ... 1 | 4
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
impaired righting response 1 | 19
increased body length 1 | 20
increased body weight 1 | 42
increased circulating calcium ... 1 | 32
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased lumbar vertebrae num... 1 | 1
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased thoracic vertebrae n... 1 | 8
mydriasis 1 | 9

Disease

ovarian cancer 49 | 8,484
osteosarcoma 37 | 7,933
psoriasis 34 | 6,685
medulloblastoma, large-cell 26 | 6,234
glioblastoma 24 | 5,572
Cancer 21 | 2,346
lung cancer 21 | 4,466
non-small cell lung cancer 21 | 2,798
atypical teratoid / rhabdoid tumor 18 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
malignant mesothelioma 18 | 3,162
subependymal giant cell astrocytoma 18 | 2,287
lung adenocarcinoma 17 | 2,713
invasive ductal carcinoma 16 | 2,950
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,795
Breast cancer 14 | 3,094
cystic fibrosis 14 | 1,665
pancreatic cancer 14 | 2,300
Carcinoma 13 | 2,147
oligodendroglioma 13 | 2,849
primitive neuroectodermal tumor 13 | 3,031
astrocytoma 12 | 1,493
interstitial cystitis 12 | 2,299
lung carcinoma 12 | 2,844
ulcerative colitis 12 | 2,087
ductal carcinoma in situ 11 | 1,745
ependymoma 11 | 2,514
group 3 medulloblastoma 11 | 2,254
pediatric high grade glioma 10 | 2,712
pilocytic astrocytoma 10 | 3,086
breast carcinoma 9 | 1,614
medulloblastoma 9 | 1,524
tuberculosis 9 | 1,557
Pick disease 8 | 1,893
Rheumatoid Arthritis 8 | 1,160
acute myeloid leukemia 8 | 780
adrenocortical carcinoma 8 | 1,427
diabetes mellitus 8 | 1,663
pituitary cancer 8 | 1,972
sonic hedgehog group medulloblastoma 8 | 1,482
astrocytic glioma 7 | 2,241
esophageal adenocarcinoma 7 | 737
primary pancreatic ductal adenocarcinoma 7 | 1,271
Autistic Disorder 6 | 320
Intellectual disability 6 | 573
dermatomyositis 6 | 933
group 4 medulloblastoma 6 | 1,875
posterior fossa group A ependymoma 6 | 1,511
spina bifida 6 | 1,064
Endometriosis 5 | 535
active Crohn's disease 5 | 918
adult high grade glioma 5 | 2,148
atypical teratoid/rhabdoid tumor 5 | 1,095
juvenile dermatomyositis 5 | 1,189
pancreatic carcinoma 5 | 567
posterior fossa group B ependymoma 5 | 1,530
Acquired metabolic disease 4 | 267
Actinic keratosis 4 | 22
Alzheimer's disease 4 | 644
Arthritis 4 | 248
Asthma 4 | 349
Atopic dermatitis 4 | 944
Barrett's esophagus 4 | 183
Hyperalgesia 4 | 71
Juvenile rheumatoid arthritis 4 | 104
Mammary Neoplasms 4 | 410
Multiple myeloma 4 | 1,327
Osteoarthritis 4 | 96
Prostatic Neoplasms 4 | 471
cutaneous lupus erythematosus 4 | 1,056
fibroadenoma 4 | 557
inflammatory breast cancer 4 | 404
Adenoid Cystic Carcinoma 3 | 99
Amyotrophic Lateral Sclerosis 3 | 431
Atherosclerosis 3 | 275
Cerebrovascular disease 3 | 231
Chronic obstructive pulmonary disease 3 | 146
Congenital ichthyosiform erythroderma 3 | 27
Coronary artery disease 3 | 240
Diarrhea 3 | 155
Esophageal Neoplasms 3 | 67
Juvenile arthritis 3 | 124
Melanoma 3 | 261
Menorrhagia 3 | 8
Obesity 3 | 616
Pain 3 | 70
Pleurisy 3 | 18
Renal Cell Carcinoma 3 | 199
Reperfusion Injury 3 | 84
acute quadriplegic myopathy 3 | 1,157
aldosterone-producing adenoma 3 | 664
colon cancer 3 | 1,475
gastric carcinoma 3 | 832
head and neck cancer and chronic obstructive pulmonary disease 3 | 237
nephrosclerosis 3 | 329
primary Sjogren syndrome 3 | 789
progressive supranuclear palsy 3 | 674
tuberculosis and treatment for 6 months 3 | 686

Tissue

Blood and immune system 82 | 17,995
Cardiovascular System 82 | 17,958
Digestive Tract 82 | 18,473
Endocrine System 82 | 18,512
Female tissues 82 | 18,647
Liver and Pancreas 82 | 18,136
Male tissues 82 | 17,969
Nervous System 82 | 18,561
Respiratory system 81 | 17,484
Skin and soft tissues 81 | 18,115
Urinary Tract 81 | 18,444

Target Family

Enzyme 53 | 4,146
Epigenetic 19 | 242
Non-IDG 6 | 11,971
TF/Epigenetic 4 | 38

UniProt Keyword

Dioxygenase 82 | 82
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lysine-specific demethylase 3B KDM3B Tbio Epigenetic -0.92399 9.25 269
Indoleamine 2,3-dioxygenase 2 IDO2 Tchem Enzyme -1.88853 82.2 208
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 OGFOD2 Tdark Enzyme 0.00000 75
Lysine-specific demethylase 6B KDM6B Tchem Epigenetic -2.06838 144.7 243
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.20847 1594.9 391
Lysine-specific demethylase PHF2 PHF2 Tbio Epigenetic -0.67973 5.14 73
Lysine-specific demethylase 4A KDM4A Tchem Epigenetic -3.00912 1030.2 233
Lysine-specific demethylase 6A KDM6A Tchem Epigenetic -2.14014 144.5 92
Lysine-specific demethylase 2B KDM2B Tchem Epigenetic -1.47312 34.5 180
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.03668 12041.6 648