Development Level

Tbio 2 | 11,445

IMPC Phenotype

vertebral fusion 1 | 23

Disease

Carcinoma 2 | 11,493
Muscular dystrophy 2 | 75
Myopathy 2 | 185
Animal Mammary Neoplasms 1 | 136
Arrhythmogenic right ventricular cardiomyopathy 1 | 30
Atrial Fibrillation 1 | 124
Autosomal recessive predisposition 1 | 1,442
Avian influenza 1 | 7
Bell Palsy 1 | 58
Breast Neoplasms 1 | 445
Bulbar palsy 1 | 19
Bulbar weakness 1 | 19
CARDIOMYOPATHY, DILATED, 1I 1 | 1
Cardiac Arrhythmia 1 | 103
Cardiac conduction abnormalities 1 | 78
Cardiomyopathy 1 | 116
Cardiomyopathy, Dilated 1 | 83
Conduction disorder of the heart 1 | 79
Congenital Fiber Type Disproportion 1 | 7
Congenital clubfoot 1 | 109
Congenital myopathy with fiber type disproportion 1 | 9
Constipation 1 | 181
Diarrhea 1 | 253
Dilated cardiomyopathy 1 | 56
Distal limb muscle weakness due to peripheral neuropathy 1 | 62
Distal muscle weakness 1 | 62
Dyschezia 1 | 135
EKG abnormalities 1 | 78
EMG: myopathic abnormalities 1 | 22
Eichsfeld type congenital muscular dystrophy 1 | 4
Electrocardiogram abnormal 1 | 81
Electrocardiogram change 1 | 78
Facial Paresis 1 | 59
Facial muscle weakness of muscles innervated by CN VII 1 | 58
Familial isolated dilated cardiomyopathy 1 | 41
Fetal Growth Retardation 1 | 189
Flexion contracture - elbow 1 | 32
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Glomerulonephritis 1 | 46
Hernias, Diaphragmatic, Congenital 1 | 17
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Hyperhomocysteinemia 1 | 37
Hypertrophic Cardiomyopathy 1 | 117
Hyporeflexia of lower limbs 1 | 10
LEFT VENTRICULAR NONCOMPACTION 10 1 | 40
LEFT VENTRICULAR NONCOMPACTION 8 1 | 40
Late-onset proximal muscle weakness 1 | 2
MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2R 1 | 1
MYOPATHY, MYOFIBRILLAR, DESMIN-RELATED 1 | 1
Malignant hyperthermia 1 | 26
Mammary Neoplasms 1 | 425
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Mastitis 1 | 48
Muscle biopsy shows dystrophic changes 1 | 39
Muscular Dystrophies 1 | 8
Muscular Dystrophy, Limb-Girdle, Type 1E 1 | 2
Myofibrillar Myopathy 1 | 9
Myofibrillar myopathy 1 1 | 6
Myopathies, Structural, Congenital 1 | 15
Neck muscle weakness 1 | 17
Nephrosis 1 | 21
Ophthalmoplegia 1 | 106
Peroneal muscle atrophy 1 | 2
Phenotypic variability 1 | 150
Progressive disorder 1 | 142
Reduced systolic function 1 | 5
Respiratory Failure 1 | 104
Respiratory insufficiency due to muscle weakness 1 | 37
Restrictive heart failure 1 | 1
Rigid spine muscular dystrophy 1 1 | 14
Rigid spine syndrome 1 | 1
Scapular weakness 1 | 23
Scapuloperoneal Syndrome, Neurogenic, Kaeser Type 1 | 1
Scapuloperoneal weakness 1 | 3
Scoliosis 1 | 44
Shoulder girdle muscle atrophy 1 | 6
Staphyloenterotoxemia 1 | 18
Stomach Neoplasms 1 | 300
Toxic shock syndrome 1 | 28
Winged scapula 1 | 23
colon cancer 1 | 1,478
limb-girdle muscular dystrophy 1 | 37
lung adenocarcinoma 1 | 2,716
lung carcinoma 1 | 2,843
non-small cell lung cancer 1 | 2,890
pancreatic cancer 1 | 2,398
primary pancreatic ductal adenocarcinoma 1 | 1,109
psoriasis 1 | 6,694

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Non-IDG 2 | 12,091

UniProt Keyword

Desmin-related myopathy 2 | 2
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Selenoprotein N SELENON Tbio Non-IDG -1.95384 87.6 96