Development Level

Tbio 33 | 11,445
Tdark 4 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 3 | 278
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal hair growth 1 | 10
abnormal posture 1 | 2
abnormal retina morphology 1 | 71
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
enlarged urinary bladder 1 | 8
increased bone mineral content 1 | 108
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
male infertility 1 | 123
tremors 1 | 39

Disease

ovarian cancer 18 | 8,520
osteosarcoma 15 | 7,950
Carcinoma 14 | 11,493
lung cancer 14 | 4,740
group 3 medulloblastoma 8 | 4,104
Kidney cancer 7 | 2,613
Multiple myeloma 7 | 1,332
medulloblastoma, large-cell 7 | 6,241
glioblastoma 6 | 5,792
primitive neuroectodermal tumor 6 | 3,035
psoriasis 6 | 6,694
Hereditary spherocytosis type 5 5 | 12
non primary Sjogren syndrome sicca 5 | 891
Treacher Collins syndrome 4 | 27
atypical teratoid / rhabdoid tumor 4 | 5,112
diabetes mellitus 4 | 1,728
ependymoma 4 | 4,679
lung adenocarcinoma 4 | 2,716
non-small cell lung cancer 4 | 2,890
Autosomal recessive predisposition 3 | 1,442
Breast cancer 3 | 3,578
CNS hypomyelination 3 | 17
Cerebellar Ataxia 3 | 304
Cleft Palate 3 | 271
Cognitive delay 3 | 608
Congenital small ears 3 | 48
Decreased projection of maxilla 3 | 66
Deficiency of upper jaw bones 3 | 66
Downward slant of palpebral fissure 3 | 158
Global developmental delay 3 | 608
Hypodontia 3 | 81
Hypomyelination 3 | 17
Hypomyelination-hypogonadotropic-hypogonadism-hypodontia syndrome 3 | 3
Hypoplasia of corpus callosum 3 | 90
Hypoplasia of the maxilla 3 | 66
Hypoplastic mandible condyle 3 | 275
Hypotrophic maxilla 3 | 66
Leukodystrophy 3 | 55
Leukodystrophy, Hypomyelinating, with Hypodontia and Hypogonadotropic Hypogonadism 3 | 3
Mandibular hypoplasia 3 | 275
Maxillary retrognathia 3 | 66
Mental and motor retardation 3 | 608
Micrognathism 3 | 275
Myopia 3 | 176
Primary hypogonadism 3 | 37
Retrusion of upper jaw bones 3 | 66
Uranostaphyloschisis 3 | 167
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
group 4 medulloblastoma 3 | 1,855
malignant mesothelioma 3 | 3,232
pediatric high grade glioma 3 | 1,064
Abnormal skeletal development 2 | 60
Abnormal upper motor neuron morphology 2 | 11
Atrophy of cerebellum 2 | 103
Babinski Reflex 2 | 100
Broad flat nasal bridge 2 | 236
Cerebellar degeneration 2 | 103
Cerebral atrophy 2 | 178
Cockayne syndrome 2 | 60
Conductive hearing loss 2 | 123
Deglutition Disorders 2 | 132
Drooling 2 | 27
Dysarthria 2 | 192
Dystonia 2 | 164
Dystonic disease 2 | 106
Frontal bossing 2 | 157
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Hyperreflexia 2 | 209
Hypogonadism, Isolated Hypogonadotropic 2 | 71
Hypogonadotropic hypogonadism 2 | 89
Hypotrophic malar bone 2 | 129
Infratentorial atrophy 2 | 103
Low Vision 2 | 174
Malar flattening 2 | 129
Midface retrusion 2 | 105
Muscle Spasticity 2 | 195
Narrow internal auditory canal 2 | 8
Nasal bridge wide 2 | 236
Oligodontia 2 | 24
Osteochondrodysplasias 2 | 72
Phenotypic variability 2 | 150
Progressive disorder 2 | 142
Retrognathia 2 | 54
Sialorrhea 2 | 28
Small midface 2 | 105
Stomach Neoplasms 2 | 300
Strabismus 2 | 270
Tooth agenesis 2 | 44
Visual Impairment 2 | 174
colon cancer 2 | 1,478
dermatomyositis 2 | 966
hepatocellular carcinoma 2 | 547
pancreatic carcinoma 2 | 562
posterior fossa group A ependymoma 2 | 468
sonic hedgehog group medulloblastoma 2 | 467
spina bifida 2 | 1,074

Tissue

Blood and immune system 37 | 16,909
Cardiovascular System 37 | 15,192
Digestive Tract 37 | 17,369
Endocrine System 37 | 18,159
Female tissues 37 | 17,400
Liver and Pancreas 37 | 16,750
Male tissues 37 | 17,142
Nervous System 37 | 16,725
Respiratory system 37 | 16,393
Skin and soft tissues 37 | 17,230
Urinary Tract 37 | 16,678

Target Family

Enzyme 38 | 4,145

UniProt Keyword

DNA-directed RNA polymerase 38 | 38
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..