Development Level

Tbio 13 | 11,445
Tclin 3 | 613
Tchem 2 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal retina morphology 1 | 71
male infertility 1 | 123
tremors 1 | 39

Disease

Carcinoma 15 | 11,493
group 3 medulloblastoma 11 | 4,104
osteosarcoma 11 | 7,950
ovarian cancer 11 | 8,520
Cancer 9 | 2,499
glioblastoma 9 | 5,792
medulloblastoma, large-cell 9 | 6,241
primitive neuroectodermal tumor 9 | 3,035
psoriasis 8 | 6,694
atypical teratoid / rhabdoid tumor 6 | 5,112
malignant mesothelioma 6 | 3,232
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
non-small cell lung cancer 5 | 2,890
Astrocytoma, Pilocytic 4 | 3,081
Xeroderma pigmentosum 4 | 43
invasive ductal carcinoma 4 | 2,951
Acute lymphoid leukemia 3 | 25
Acute myeloid leukemia, disease 3 | 30
Acute promyelocytic leukemia, FAB M3 3 | 11
Adenocarcinoma of pancreas 3 | 14
Autosomal recessive predisposition 3 | 1,442
Bell Palsy 3 | 58
Blepharoptosis 3 | 231
Breast cancer 3 | 3,578
Facial Paresis 3 | 59
Facial muscle weakness of muscles innervated by CN VII 3 | 58
Lymphomatous meningitis 3 | 3
Malignant tumor of ovary 3 | 25
Meningeal Leukemia 3 | 7
Metastatic Breast Carcinoma 3 | 21
adrenocortical carcinoma 3 | 1,428
diabetes mellitus 3 | 1,728
lung cancer 3 | 4,740
Abnormal vision 2 | 52
Adult onset 2 | 82
Atrophic condition of skin 2 | 25
Chronic progressive external ophthalmoplegia 2 | 26
Cockayne syndrome 2 | 60
Cognitive delay 2 | 608
Colorectal Neoplasms 2 | 243
Creatine phosphokinase serum increased 2 | 110
Cryptorchidism 2 | 296
Deafness 2 | 198
Decreased activity of cytochrome C oxidase in muscle tissue 2 | 10
Deglutition Disorders 2 | 132
Elevated creatine kinase 2 | 110
Elevated hepatic transaminases 2 | 81
Epilepsy 2 | 792
Familial adenomatous polyposis 2 | 32
Global developmental delay 2 | 608
Hepatic enzyme increased 2 | 81
Hepatomegaly 2 | 285
Highly variable severity 2 | 157
Impaired exercise tolerance 2 | 42
Increased serum lactate 2 | 60
Kidney cancer 2 | 2,613
Liver Dysfunction 2 | 99
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Lynch syndrome 2 | 35
Mental and motor retardation 2 | 608
Multiple mitochondrial DNA (mtDNA) deletions 2 | 5
Muscle hypotonia 2 | 571
Muscle weakness of limb 2 | 21
Muscle weakness, progressive 2 | 22
Neuropathy 2 | 261
Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions, Autosomal Dominant 1 2 | 5
Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 1 2 | 5
Progressive disorder 2 | 142
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Sensorineural Hearing Loss (disorder) 2 | 284
Spider Veins 2 | 17
Subclinical abnormal liver function tests 2 | 81
Telangiectasis 2 | 36
Transaminases increased 2 | 81
Variable expressivity 2 | 157
acute myeloid leukemia 2 | 783
colon cancer 2 | 1,478
gastric cancer 2 | 459
group 4 medulloblastoma 2 | 1,855
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
pediatric high grade glioma 2 | 1,064
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010
Blindness, Cortical 1 | 24
Cortical visual impairment 1 | 24
Dysphonia 1 | 7
Ectropion 1 | 38
Mitochondrial encephalomyopathy 1 | 15
Mobius syndrome 1 | 6
Werner syndrome 1 | 29
Xeroderma pigmentosum group F 1 | 22

Tissue

Blood and immune system 20 | 16,909
Cardiovascular System 20 | 15,192
Digestive Tract 20 | 17,369
Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Male tissues 20 | 17,142
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678

Target Family

Enzyme 19 | 4,145
Non-IDG 1 | 12,091

UniProt Keyword

DNA-directed DNA polymerase 20 | 20
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA polymerase iota POLI Tbio Enzyme -3.24008 1701.9 333
Non-canonical poly(A) RNA polymerase PAPD5 PAPD5 Tbio Enzyme -0.76848 4.57 124
DNA polymerase nu POLN Tbio Enzyme -2.17621 148.9 60
DNA polymerase kappa POLK Tbio Enzyme -2.42142 256.3 224
DNA polymerase subunit gamma-1 POLG Tchem Enzyme -2.63005 414.1 128
DNA polymerase theta POLQ Tbio Enzyme -1.61640 40.0 57
DNA polymerase zeta catalytic subunit REV3L Tbio Enzyme -2.20108 158.5 41
Chromatin accessibility complex protein 1 CHRAC1 Tdark Non-IDG -0.47787 3.02 120
DNA polymerase subunit gamma-2, mitochondrial POLG2 Tbio Enzyme -1.34785 20.3 105
DNA polymerase delta catalytic subunit POLD1 Tclin Enzyme -2.06760 110.4 225