Development Level

Tbio 56 | 10,625
Tdark 19 | 7,003
Tchem 7 | 1,890

IMPC Term

preweaning lethality, complete... 9 | 633
embryonic lethality prior to o... 5 | 148
embryonic lethality prior to t... 4 | 187
decreased body weight 2 | 174
hypoactivity 2 | 89
increased heart weight 2 | 37
abnormal QRS complex 1 | 25
abnormal behavior 1 | 226
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal locomotor activation 1 | 26
abnormal placement of pupils 1 | 4
abnormal seminal vesicle morph... 1 | 47
abnormal spleen morphology 1 | 36
abnormal vocalization 1 | 21
anophthalmia 1 | 20
corneal opacity 1 | 25
decreased lymphocyte cell numb... 1 | 9
increased body length 1 | 20
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased exploration in new e... 1 | 56
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased neutrophil cell numb... 1 | 15
male infertility 1 | 62
narrow eye opening 1 | 15
pale yolk sac 1 | 12
preweaning lethality, incomple... 1 | 260
small testis 1 | 37
straub tail 1 | 26
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

ovarian cancer 42 | 8,484
osteosarcoma 41 | 7,933
medulloblastoma, large-cell 26 | 6,234
Breast cancer 23 | 3,094
Cancer 23 | 2,346
lung cancer 23 | 4,466
psoriasis 23 | 6,685
glioblastoma 20 | 5,572
group 3 medulloblastoma 20 | 2,254
malignant mesothelioma 20 | 3,162
primitive neuroectodermal tumor 18 | 3,031
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,289
atypical teratoid / rhabdoid tumor 15 | 4,369
lung adenocarcinoma 14 | 2,713
non-small cell lung cancer 13 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
oligodendroglioma 11 | 2,849
Carcinoma 10 | 2,147
Fanconi's anemia 10 | 50
astrocytic glioma 10 | 2,241
invasive ductal carcinoma 10 | 2,950
Bloom syndrome 9 | 30
Mammary Neoplasms 9 | 410
pediatric high grade glioma 9 | 2,712
sonic hedgehog group medulloblastoma 9 | 1,482
Ataxia telangiectasia 8 | 31
Waldenstrons macroglobulinemia 8 | 765
adrenocortical carcinoma 8 | 1,427
colon cancer 8 | 1,475
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
Multiple myeloma 7 | 1,327
Pick disease 7 | 1,893
Rheumatoid Arthritis 7 | 1,160
diabetes mellitus 7 | 1,663
ependymoma 7 | 2,514
Hereditary Breast and Ovarian Cancer Syndrome 6 | 14
Nijmegen breakage syndrome 6 | 23
Werner syndrome 6 | 29
acute myeloid leukemia 6 | 780
acute quadriplegic myopathy 6 | 1,157
atypical teratoid/rhabdoid tumor 6 | 1,095
breast carcinoma 6 | 1,614
nasopharyngeal carcinoma 6 | 1,056
pancreatic cancer 6 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
posterior fossa group A ependymoma 6 | 1,511
Anemia 5 | 252
Neoplastic Syndromes, Hereditary 5 | 48
Prostatic Neoplasms 5 | 471
Severe Combined Immunodeficiency 5 | 46
astrocytoma 5 | 1,493
ductal carcinoma in situ 5 | 1,745
ovarian neoplasm 5 | 97
progressive supranuclear palsy 5 | 674
Alzheimer's disease 4 | 644
Breast Cancer, Familial 4 | 12
DNA ligase IV deficiency 4 | 6
Endometriosis 4 | 535
Fanconi Anemia 4 | 19
Malignant neoplasm of breast 4 | 63
Omenn Syndrome 4 | 14
adult high grade glioma 4 | 2,148
dermatomyositis 4 | 933
juvenile dermatomyositis 4 | 1,189
non primary Sjogren syndrome sicca 4 | 840
posterior fossa group B ependymoma 4 | 1,530
primary Sjogren syndrome 4 | 789
Adenoid Cystic Carcinoma 3 | 99
Atopic dermatitis 3 | 944
Cowden disease 3 | 16
Hereditary breast ovarian cancer 3 | 6
Histiocytic medullary reticulosis (disorder) 3 | 3
Li-Fraumeni Syndrome 3 | 13
Pancreatic Neoplasm 3 | 79
Pancreatic carcinoma, familial 3 | 8
Prostate cancer 3 | 172
Reticuloendotheliosis, familial, with eosinophilia 3 | 3
Seckel syndrome 3 | 34
Xeroderma pigmentosum 3 | 41
hepatocellular carcinoma 3 | 532
spina bifida 3 | 1,064
tuberculosis 3 | 1,557
tuberculosis and treatment for 6 months 3 | 686
Amyotrophic Lateral Sclerosis 2 | 431
Cockayne syndrome 2 | 54
Disease Progression 2 | 125
Liver carcinoma 2 | 217
Malignant neoplasm of prostate 2 | 67
Neurodegenerative disease 2 | 383
Peripheral Neuropathy 2 | 303
Stomach Neoplasms 2 | 282
cystic fibrosis 2 | 1,665
glioblastoma multiforme 2 | 347
inflammatory breast cancer 2 | 404
medulloblastoma 2 | 1,524
pancreatic carcinoma 2 | 567
pilocytic astrocytoma 2 | 3,086
primary pancreatic ductal adenocarcinoma 2 | 1,271
subependymal giant cell astrocytoma 2 | 2,287
substance-related disorder 2 | 105

Tissue

Female tissues 73 | 18,647
Liver and Pancreas 73 | 18,136
Male tissues 73 | 17,969
Blood and immune system 72 | 17,995
Cardiovascular System 72 | 17,958
Digestive Tract 72 | 18,473
Endocrine System 72 | 18,512
Nervous System 72 | 18,561
Urinary Tract 72 | 18,444
Skin and soft tissues 71 | 18,115
Respiratory system 70 | 17,484

Target Family

Non-IDG 50 | 11,971
Enzyme 25 | 4,146
Transcription Factor 4 | 1,400
Epigenetic 2 | 242
Kinase 1 | 634

UniProt Keyword

DNA recombination 82 | 82
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
V(D)J recombination-activating protein 1 RAG1 Tbio Non-IDG -3.00063 1061.1 65
Replication protein A 32 kDa subunit RPA2 Tbio Non-IDG -1.76828 59.7 468
Probable crossover junction endonuclease EME2 EME2 Tbio Enzyme -1.53403 32.3 56
Transcriptional repressor protein YY1 YY1 Tbio Transcription Factor -2.75991 594.0 437
Protein artemis DCLRE1C Tbio Non-IDG -1.63807 45.4 225
Endogenous retrovirus group K member 8 Pol protein ERVK-8 Tdark Enzyme 0.00000 0
Endogenous retrovirus group K member 7 Pol protein ERVK-7 Tdark Enzyme 0.00000 0
Endogenous retrovirus group K member 25 Pol protein ERVK-25 Tdark Enzyme 0.00000 0
Endogenous retrovirus group K member 113 Pol protein HERVK_113 Tdark Enzyme 0.00000 0
DNA ligase 4 LIG4 Tbio Enzyme -2.11773 136.0 194