Development Level

Tbio 397 | 11,445
Tdark 70 | 6,588
Tchem 44 | 1,598
Tclin 24 | 613

Collection

RFA-RM-18-021 9 | 328
GPCR: IDG Consortium (Targets) 4 | 126
Kinase: IDG Consortium (Target... 4 | 125
Kinase: IDG Consortium (Comple... 2 | 37
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 34 | 979
preweaning lethality, incomple... 12 | 499
abnormal behavior 10 | 298
abnormal embryo size 9 | 220
embryonic lethality prior to t... 9 | 278
decreased grip strength 8 | 116
decreased total body fat amoun... 8 | 207
decreased circulating glucose ... 7 | 126
embryonic lethality prior to o... 7 | 239
decreased body weight 6 | 161
decreased vertical activity 6 | 208
embryonic growth retardation 6 | 106
hypoactivity 6 | 132
abnormal kidney morphology 5 | 65
decreased circulating choleste... 5 | 93
decreased circulating serum al... 5 | 82
increased mean corpuscular hem... 5 | 96
increased startle reflex 5 | 112
abnormal behavioral response t... 4 | 66
abnormal seminal vesicle morph... 4 | 114
abnormal sleep behavior 4 | 70
anophthalmia 4 | 33
decreased bone mineral density 4 | 126
decreased circulating aspartat... 4 | 34
decreased circulating triglyce... 4 | 79
decreased lymphocyte cell numb... 4 | 83
decreased mean corpuscular hem... 4 | 50
edema 4 | 59
enlarged heart 4 | 210
impaired glucose tolerance 4 | 75
increased bone mineral content 4 | 108
increased circulating sodium l... 4 | 71
increased or absent threshold ... 4 | 101
prenatal lethality prior to he... 4 | 87
abnormal facial morphology 3 | 17
abnormal limb morphology 3 | 13
abnormal retina morphology 3 | 71
decreased bone mineral content 3 | 151
decreased circulating HDL chol... 3 | 68
decreased circulating LDL chol... 3 | 38
decreased circulating alanine ... 3 | 47
decreased circulating fructosa... 3 | 30
decreased fasted circulating g... 3 | 65
decreased prepulse inhibition 3 | 82
decreased startle reflex 3 | 75
hyperactivity 3 | 148
improved glucose tolerance 3 | 79
increased body weight 3 | 25
increased circulating chloride... 3 | 41
increased fasted circulating g... 3 | 76
increased hemoglobin content 3 | 45
increased lean body mass 3 | 172
increased mean corpuscular hem... 3 | 36
increased mean corpuscular vol... 3 | 92
increased monocyte cell number 3 | 63
increased total body fat amoun... 3 | 134
abnormal bone structure 2 | 187
abnormal coat- hair morphology 2 | 19
abnormal coat-hair pigmentatio... 2 | 64
abnormal craniofacial morpholo... 2 | 33
abnormal embryo turning 2 | 31
abnormal epididymis morphology 2 | 42
abnormal lens morphology 2 | 81
abnormal limb bud morphology 2 | 17
abnormal liver morphology 2 | 17
abnormal locomotor behavior 2 | 24
abnormal neural tube closure 2 | 46
abnormal testis morphology 2 | 43
cardiovascular system phenotyp... 2 | 36
cataract 2 | 92
cleft palate 2 | 8
convulsive seizures 2 | 13
decreased body length 2 | 101
decreased circulating chloride... 2 | 30
decreased circulating potassiu... 2 | 20
decreased circulating total pr... 2 | 49
decreased mean corpuscular hem... 2 | 31
decreased mean corpuscular vol... 2 | 79
enlarged epididymis 2 | 31
hemorrhage 2 | 23
increased blood urea nitrogen ... 2 | 48
increased circulating HDL chol... 2 | 80
increased circulating aspartat... 2 | 15
increased circulating choleste... 2 | 66
increased circulating phosphat... 2 | 26
increased erythrocyte cell num... 2 | 39
increased heart rate 2 | 23
increased heart weight 2 | 62
increased hematocrit 2 | 46
increased prepulse inhibition 2 | 32
increased red blood cell distr... 2 | 34
limb grasping 2 | 41
pallor 2 | 34
persistence of hyaloid vascula... 2 | 33
prenatal lethality 2 | 28
short tibia 2 | 97
small testis 2 | 58
syndactyly 2 | 23
thrombocytopenia 2 | 56
tremors 2 | 39

Disease

Carcinoma 344 | 11,493
ovarian cancer 264 | 8,520
osteosarcoma 260 | 7,950
glioblastoma 225 | 5,792
medulloblastoma, large-cell 221 | 6,241
atypical teratoid / rhabdoid tumor 205 | 5,112
psoriasis 185 | 6,694
ependymoma 182 | 4,679
adult high grade glioma 148 | 3,801
Astrocytoma, Pilocytic 142 | 3,081
lung cancer 124 | 4,740
oligodendroglioma 122 | 2,850
group 3 medulloblastoma 111 | 4,104
astrocytic glioma 109 | 2,597
primitive neuroectodermal tumor 109 | 3,035
lung carcinoma 107 | 2,843
malignant mesothelioma 103 | 3,232
Breast cancer 100 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 99 | 2,989
invasive ductal carcinoma 97 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 94 | 2,955
subependymal giant cell astrocytoma 92 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 91 | 3,291
Kidney cancer 84 | 2,613
non-small cell lung cancer 80 | 2,890
interstitial cystitis 77 | 2,312
lung adenocarcinoma 77 | 2,716
pancreatic cancer 76 | 2,398
tuberculosis 76 | 2,010
Pick disease 75 | 1,894
group 4 medulloblastoma 66 | 1,855
pituitary cancer 65 | 1,972
Schizophrenia 64 | 1,160
Cancer 59 | 2,499
pancreatic ductal adenocarcinoma liver metastasis 57 | 1,962
ulcerative colitis 57 | 1,819
Multiple myeloma 52 | 1,332
ductal carcinoma in situ 50 | 1,745
breast carcinoma 49 | 1,638
diabetes mellitus 48 | 1,728
primary pancreatic ductal adenocarcinoma 46 | 1,109
spina bifida 46 | 1,074
cystic fibrosis 43 | 1,696
astrocytoma 42 | 1,146
Autosomal recessive predisposition 41 | 1,442
pediatric high grade glioma 41 | 1,064
Rheumatoid arthritis 39 | 1,191
acute quadriplegic myopathy 39 | 1,158
cutaneous lupus erythematosus 38 | 1,057
Bipolar Disorder 37 | 666
adrenocortical carcinoma 37 | 1,428
juvenile dermatomyositis 37 | 1,187
colon cancer 36 | 1,478
Liver Cirrhosis, Experimental 35 | 769
Epilepsy 34 | 792
gastric carcinoma 34 | 807
Intellectual disability 33 | 1,016
dermatomyositis 31 | 966
aldosterone-producing adenoma 29 | 665
Alzheimer's disease 28 | 658
Waldenstrons macroglobulinemia 28 | 765
non primary Sjogren syndrome sicca 28 | 891
hepatocellular carcinoma 27 | 547
mucosa-associated lymphoid tissue lymphoma 27 | 484
Neurodegenerative disease 26 | 414
nasopharyngeal carcinoma 26 | 1,058
Cognitive delay 25 | 608
Global developmental delay 25 | 608
Mental and motor retardation 25 | 608
active Crohn's disease 25 | 922
medulloblastoma 24 | 720
Parkinson's disease 23 | 392
acute myeloid leukemia 23 | 783
Dull intelligence 22 | 645
Liver cancer 22 | 604
Low intelligence 22 | 645
Mental Retardation 22 | 645
Mental deficiency 22 | 645
Poor school performance 22 | 645
Seizures 22 | 596
progressive supranuclear palsy 22 | 676
Depressive disorder 21 | 409
primary Sjogren syndrome 21 | 735
Amyotrophic lateral sclerosis 20 | 451
Atopic dermatitis 20 | 952
Melanoma 20 | 711
Muscle hypotonia 19 | 571
esophageal adenocarcinoma 19 | 737
sonic hedgehog group medulloblastoma 19 | 467
Down syndrome 18 | 499
Obesity 18 | 678
Skin cancer 18 | 469
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 510
posterior fossa group A ependymoma 18 | 468
Alcoholic Intoxication, Chronic 17 | 289
fibroadenoma 17 | 559
pancreatic carcinoma 17 | 562
Duchenne muscular dystrophy 16 | 601
Kidney disease 16 | 430
Type 2 diabetes mellitus 16 | 272

Tissue

Endocrine System 526 | 18,159
Digestive Tract 515 | 17,369
Female tissues 512 | 17,400
Male tissues 512 | 17,142
Skin and soft tissues 510 | 17,230
Liver and Pancreas 505 | 16,750
Nervous System 505 | 16,725
Urinary Tract 501 | 16,678
Blood and immune system 498 | 16,909
Respiratory system 489 | 16,393
Cardiovascular System 460 | 15,192

Target Family

Non-IDG 362 | 12,091
Enzyme 101 | 4,145
Kinase 24 | 634
Ion Channel 19 | 344
Transporter 18 | 473
GPCR 9 | 408
Transcription Factor 2 | 1,400

UniProt Keyword

Cytoplasmic vesicle 535 | 535
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rab11 family-interacting protein 5 RAB11FIP5 Tbio Non-IDG -1.52843 34.5 62
Acrosomal protein SP-10 ACRV1 Tbio Non-IDG -2.30250 194.8 128
Synaptotagmin-7 SYT7 Tbio Non-IDG -1.75931 60.3 170
Gamma-aminobutyric acid receptor-associated protein-like 3 GABARAPL3 Tdark Non-IDG -0.16137 0.12 0
TBC1 domain family member 2A TBC1D2 Tbio Non-IDG -1.28188 18.5 80
Centrosomal protein of 131 kDa CEP131 Tbio Non-IDG -1.78486 61.9 82
Sterol regulatory element-binding protein 2 SREBF2 Tchem Transcription Factor -2.61148 361.0 205
Sterol regulatory element-binding protein cleavage-activating protein SCAP Tbio Non-IDG -1.85010 73.9 172
Charged multivesicular body protein 4a CHMP4A Tbio Non-IDG -1.17768 16.3 29
Testis-expressed protein 101 TEX101 Tbio Non-IDG -1.34939 22.8 30