Development Level

Tbio 11 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613

IMPC Phenotype

cardiovascular system phenotyp... 1 | 36
decreased heart weight 1 | 27
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
increased circulating sodium l... 1 | 71
shortened RR interval 1 | 17

Disease

lung cancer 9 | 4,740
psoriasis 9 | 6,694
Carcinoma 8 | 11,493
lung carcinoma 8 | 2,843
lung adenocarcinoma 7 | 2,716
osteosarcoma 7 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Autosomal recessive predisposition 6 | 1,442
ovarian cancer 6 | 8,520
Cancer 5 | 2,499
Meningitis 5 | 67
cutaneous lupus erythematosus 5 | 1,057
interstitial cystitis 5 | 2,312
non-small cell lung cancer 5 | 2,890
tuberculosis 5 | 2,010
Immunologic Deficiency Syndromes 4 | 113
Skin cancer 4 | 469
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
pancreatic cancer 4 | 2,398
primary Sjogren syndrome 4 | 735
Complement deficiency 3 | 14
Complement deficiency disease 3 | 6
Kidney cancer 3 | 2,613
Liver Cirrhosis, Experimental 3 | 769
Melanoma 3 | 711
glioblastoma 3 | 5,792
head and neck cancer and chronic obstructive pulmonary disease 3 | 239
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
nasopharyngeal carcinoma 3 | 1,058
ulcerative colitis 3 | 1,819
Anemia 2 | 365
Atopic dermatitis 2 | 952
Autistic Disorder 2 | 364
Breast cancer 2 | 3,578
C8 deficiency 2 | 2
Carcinoma, Hepatocellular 2 | 228
Encephalitis 2 | 64
Hemophagocytic lymphohistiocytosis 2 | 30
Increased susceptibility to Neisseria meningitidis infections 2 | 4
Liver carcinoma 2 | 240
Neisseriaceae Infections 2 | 3
Paroxysmal nocturnal hemoglobinuria 2 | 10
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
diabetes mellitus 2 | 1,728
malignant mesothelioma 2 | 3,232
nephrosclerosis 2 | 333
sarcoidosis 2 | 370
Age related macular degeneration 1 | 72
Aplastic Anemia 1 | 21
Ascariasis 1 | 7
Bacterial vaginosis 1 | 15
Behcet's disease 1 | 89
Bone marrow hypocellularity 1 | 20
Calcinosis 1 | 70
Celiac disease 1 | 116
Cholera 1 | 34
Comatose 1 | 56
Common variable immunodeficiency 1 | 101
Cowpox 1 | 16
Dengue disease 1 | 23
Drug allergy 1 | 36
Edema, generalized 1 | 2
Endocarditis 1 | 19
Erythema 1 | 58
Familial Hemophagocytic Lymphocytosis 1 | 4
Fibromyalgia 1 | 19
Gas gangrene 1 | 17
Heart Valve Diseases 1 | 25
Heart valve disease 1 | 39
Hepatitis 1 | 67
Human immunodeficiency virus infectious disease 1 | 138
Hypermobility syndrome 1 | 17
Hypertriglyceridemia result 1 | 37
Idiopathic pulmonary fibrosis 1 | 23
Irritation - emotion 1 | 68
Lipodystrophy 1 | 40
Lymphadenopathy 1 | 62
Lymphocytic gastritis 1 | 4
Lymphoproliferative syndrome 1 | 58
Macular degeneration 1 | 65
Non-alcoholic Fatty Liver Disease 1 | 42
Oral Submucous Fibrosis 1 | 20
Osgood-Schlatter's disease 1 | 6
Ovarian serous cystadenocarcinoma 1 | 5
Patellofemoral pain syndrome 1 | 10
Psoriatic arthritis 1 | 86
Recurrent infections 1 | 48
Salpingitis 1 | 6
Severe Dengue 1 | 3
Skin disease 1 | 66
Stiff-Person syndrome 1 | 12
Takayasu's arteritis 1 | 53
Toxic shock syndrome 1 | 28
Vitiligo 1 | 73
chronic kidney disease 1 | 90
type I diabetes mellitus 1 | 22

Tissue

Liver and Pancreas 13 | 16,750
Urinary Tract 13 | 16,678
Endocrine System 12 | 18,159
Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Female tissues 11 | 17,400
Male tissues 11 | 17,142
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Cardiovascular System 10 | 15,192
Nervous System 9 | 16,725

Target Family

Non-IDG 10 | 12,091
Enzyme 4 | 4,145

UniProt Keyword

Cytolysis 14 | 14
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Perforin-1 PRF1 Tchem Non-IDG -3.20526 1546.3 367
Granzyme M GZMM Tbio Enzyme -2.65427 401.1 77
Granzyme A GZMA Tbio Enzyme -2.51799 315.2 275
Granzyme H GZMH Tbio Enzyme -1.86288 70.9 130
Granzyme B GZMB Tchem Enzyme -3.33029 2026.7 762
Complement C5 C5 Tclin Non-IDG -2.26690 170.8 448
Complement component C6 C6 Tbio Non-IDG -1.55226 36.1 153
Complement component C9 C9 Tbio Non-IDG -1.88910 74.6 285
Complement component C7 C7 Tbio Non-IDG -1.39617 24.3 164
MHC class I polypeptide-related sequence B MICB Tbio Non-IDG 0.00000 182