Development Level

Tbio 164 | 11,445
Tclin 10 | 613
Tchem 9 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

decreased vertical activity 7 | 208
enlarged heart 7 | 210
preweaning lethality, complete... 7 | 979
abnormal heart morphology 4 | 162
embryonic lethality prior to t... 4 | 278
decreased circulating insulin ... 3 | 76
embryonic lethality prior to o... 3 | 239
increased mean corpuscular vol... 3 | 92
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
decreased circulating creatini... 2 | 39
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased lean body mass 2 | 135
hydrometra 2 | 53
hyperactivity 2 | 148
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased circulating HDL chol... 2 | 80
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
abnormal behavioral response t... 1 | 66
abnormal brain morphology 1 | 13
abnormal coat- hair morphology 1 | 19
abnormal gait 1 | 69
abnormal lung morphology 1 | 26
abnormal neural tube morpholog... 1 | 12
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased B cell number 1 | 5
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
enlarged testis 1 | 6
enlarged uterus 1 | 11
female infertility 1 | 60
hydroencephaly 1 | 14
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating potassiu... 1 | 29
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
male infertility 1 | 123
pale yolk sac 1 | 25
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

psoriasis 96 | 6,694
Cancer 80 | 2,499
interstitial cystitis 55 | 2,312
lung cancer 53 | 4,740
ovarian cancer 52 | 8,520
tuberculosis 52 | 2,010
Carcinoma 50 | 11,493
malignant mesothelioma 48 | 3,232
Asthma 45 | 385
glioblastoma 45 | 5,792
ulcerative colitis 44 | 1,819
adult high grade glioma 42 | 3,801
osteosarcoma 40 | 7,950
Multiple Sclerosis 39 | 540
lung carcinoma 39 | 2,843
non-small cell lung cancer 39 | 2,890
Hypersensitivity reaction type II disease 38 | 253
Rheumatoid arthritis 37 | 1,191
Arthritis 36 | 290
Inflammatory bowel disease 36 | 151
Breast cancer 34 | 3,578
cystic fibrosis 34 | 1,696
lung adenocarcinoma 34 | 2,716
medulloblastoma, large-cell 34 | 6,241
atypical teratoid / rhabdoid tumor 33 | 5,112
invasive ductal carcinoma 32 | 2,951
Dermatitis 31 | 157
Pneumonia 30 | 174
diabetes mellitus 30 | 1,728
ependymoma 30 | 4,679
pancreatic cancer 30 | 2,398
Astrocytoma, Pilocytic 29 | 3,081
Lung disease 28 | 142
Hypersensitivity 27 | 63
Influenza 27 | 142
cutaneous lupus erythematosus 27 | 1,057
Allergic hypersensitivity disease 26 | 126
Hypereosinophilic syndrome 26 | 71
Atopic dermatitis 25 | 952
colon cancer 25 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
Kidney disease 24 | 430
Atherosclerosis 23 | 291
Breast Neoplasms 23 | 445
Mammary Neoplasms 23 | 425
Liver Cirrhosis, Experimental 22 | 769
Schizophrenia 22 | 1,160
periodontitis 22 | 293
Allergic rhinitis 21 | 94
Pulmonary Fibrosis 21 | 106
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
nasopharyngeal carcinoma 21 | 1,058
sarcoidosis 21 | 370
Anemia 20 | 365
breast carcinoma 20 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
Arthritis, Rheumatoid 19 | 174
Endometriosis 19 | 540
Inflammation 19 | 120
Hepatitis C 18 | 94
Malaria 18 | 160
Mesothelioma, Malignant 18 | 105
Coronary artery disease 17 | 268
Dermatitis, Atopic 17 | 37
Vascular disease 17 | 319
active Crohn's disease 17 | 922
active ulcerative colitis 17 | 764
ductal carcinoma in situ 17 | 1,745
pituitary cancer 17 | 1,972
Chemical and Drug Induced Liver Injury 16 | 195
Heart disease 16 | 306
Hepatitis B 16 | 108
Leishmaniasis 16 | 47
Major Depressive Disorder 16 | 301
hepatocellular carcinoma 16 | 547
Common cold 15 | 67
Human immunodeficiency virus infectious disease 15 | 138
Leukopenia 15 | 72
Prostatic Neoplasms 15 | 495
Thrombocytopenia 15 | 197
Unipolar Depression 15 | 250
Vasculitis 15 | 80
Acquired immunodeficiency syndrome 14 | 197
Crohn's disease 14 | 321
Dermatitis, Allergic Contact 14 | 67
Fever 14 | 138
Glomerulonephritis 14 | 46
Hypertension 14 | 396
group 3 medulloblastoma 14 | 4,104
oligodendroglioma 14 | 2,850
subependymal giant cell astrocytoma 14 | 2,287
Abortion, Spontaneous 13 | 109
Diarrhea 13 | 253
Hepatitis, Autoimmune 13 | 17
Liver disease 13 | 237
Obesity 13 | 678
Spontaneous abortion 13 | 113
head and neck cancer 13 | 271
juvenile dermatomyositis 13 | 1,187
mucosa-associated lymphoid tissue lymphoma 13 | 484

Tissue

Blood and immune system 164 | 16,909
Digestive Tract 162 | 17,369
Endocrine System 162 | 18,159
Skin and soft tissues 159 | 17,230
Female tissues 156 | 17,400
Urinary Tract 155 | 16,678
Liver and Pancreas 154 | 16,750
Male tissues 152 | 17,142
Respiratory system 143 | 16,393
Nervous System 134 | 16,725
Cardiovascular System 114 | 15,192

Target Family

Non-IDG 181 | 12,091
Enzyme 5 | 4,145

UniProt Keyword

Cytokine 186 | 186
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thrombopoietin THPO Tbio Non-IDG -3.23551 1632.3 440
CKLF-like MARVEL transmembrane domain-containing protein 6 CMTM6 Tdark Non-IDG -0.56950 2.80 85
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
C-C motif chemokine 3-like 1 CCL3L1 Tbio Non-IDG -1.80717 51.3 142
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
C-C motif chemokine 13 CCL13 Tbio Non-IDG -2.02640 99.2 264
Interleukin-19 IL19 Tbio Non-IDG -1.97214 102.3 249
C-C motif chemokine 20 CCL20 Tbio Non-IDG -3.10283 1250.3 496
Tumor necrosis factor ligand superfamily member 9 TNFSF9 Tbio Non-IDG -2.23604 185.9 371
Interferon alpha-1/13 IFNA13 Tbio Non-IDG -3.87160 7663.4 500