Development Level

Tbio 19 | 11,445
Tdark 8 | 6,588
Tchem 6 | 1,598

IMPC Phenotype

abnormal embryo size 1 | 220
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased fasted circulating g... 1 | 76
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
urinary bladder obstruction 1 | 4

Disease

ovarian cancer 21 | 8,520
Carcinoma 18 | 11,493
osteosarcoma 18 | 7,950
medulloblastoma, large-cell 15 | 6,241
psoriasis 15 | 6,694
Cancer 14 | 2,499
lung cancer 14 | 4,740
group 3 medulloblastoma 13 | 4,104
Breast cancer 12 | 3,578
glioblastoma 12 | 5,792
atypical teratoid / rhabdoid tumor 11 | 5,112
non-small cell lung cancer 11 | 2,890
lung adenocarcinoma 10 | 2,716
malignant mesothelioma 10 | 3,232
primitive neuroectodermal tumor 10 | 3,035
adult high grade glioma 8 | 3,801
ependymoma 8 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
subependymal giant cell astrocytoma 7 | 2,287
Atopic dermatitis 6 | 952
Pick disease 6 | 1,894
adrenocortical carcinoma 6 | 1,428
breast carcinoma 6 | 1,638
ductal carcinoma in situ 6 | 1,745
nasopharyngeal carcinoma 6 | 1,058
pancreatic cancer 6 | 2,398
acute quadriplegic myopathy 5 | 1,158
astrocytic glioma 5 | 2,597
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
oligodendroglioma 5 | 2,850
progressive supranuclear palsy 5 | 676
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Astrocytoma, Pilocytic 4 | 3,081
Endometriosis 4 | 540
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,109
Carcinoma, Hepatocellular 3 | 228
Liver Cirrhosis, Experimental 3 | 769
Liver carcinoma 3 | 240
Multiple myeloma 3 | 1,332
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cutaneous lupus erythematosus 3 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
primary Sjogren syndrome 3 | 735
Amyotrophic lateral sclerosis 2 | 451
Animal Mammary Neoplasms 2 | 136
Breast Neoplasms 2 | 445
Colonic Neoplasms 2 | 142
Colorectal Neoplasms 2 | 243
Duchenne muscular dystrophy 2 | 601
Hydrocephalus 2 | 152
Immune system cancer 2 | 140
Kidney cancer 2 | 2,613
Lung Neoplasms 2 | 232
Lymphoid leukemia 2 | 160
Mammary Neoplasms 2 | 425
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Mental Depression 2 | 333
Myocardial Ischemia 2 | 169
Ovarian Neoplasms 2 | 102
Peripheral vascular disease 2 | 87
Polycystic ovary syndrome 2 | 360
Prostatic Neoplasms 2 | 495
Type 2 diabetes mellitus 2 | 272
active ulcerative colitis 2 | 764
astrocytoma 2 | 1,146
dermatomyositis 2 | 966
group 4 medulloblastoma 2 | 1,855
hepatocellular carcinoma 2 | 547
interstitial lung disease 2 | 298
ovarian neoplasm 2 | 99
pediatric high grade glioma 2 | 1,064
posterior fossa group A ependymoma 2 | 468
spina bifida 2 | 1,074
tuberculosis and treatment for 6 months 2 | 409
Acquired immunodeficiency syndrome 1 | 197
Ciliary Motility Disorders 1 | 38
Ciliopathy 1 | 71
Fibrosis 1 | 44
Kartagener Syndrome 1 | 38
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Salivary Gland Neoplasms 1 | 46
Sarcoma 1 | 62
chronic kidney disease 1 | 90

Tissue

Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Female tissues 30 | 17,400
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Nervous System 30 | 16,725
Respiratory system 30 | 16,393
Skin and soft tissues 30 | 17,230
Blood and immune system 29 | 16,909
Urinary Tract 29 | 16,678
Cardiovascular System 28 | 15,192

Target Family

Non-IDG 33 | 12,091

UniProt Keyword

Cyclin 33 | 33
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CDK5 and ABL1 enzyme substrate 2 CABLES2 Tdark Non-IDG 0.08 1.29 75
Cyclin-Y CCNY Tbio Non-IDG -1.48139 30.1 120
G2/mitotic-specific cyclin-B3 CCNB3 Tbio Non-IDG -1.07824 12.1 272
Cyclin-O CCNO Tbio Non-IDG -1.55274 37.4 183
Putative cyclin-Y-like protein 3 CCNYL3 Tdark Non-IDG 0.00000 0
Cyclin-Y-like protein 2 CCNYL2 Tdark Non-IDG 0.00000 0
Putative cyclin-related protein FAM58B FAM58BP Tdark Non-IDG 0.00000 0
Cyclin-A1 CCNA1 Tbio Non-IDG -2.02564 107.2 314
Cyclin-F CCNF Tbio Non-IDG -1.55907 38.3 173
Cyclin-L1 CCNL1 Tbio Non-IDG -0.82661 6.96 183