Development Level

Tbio 48 | 10,625
Tchem 13 | 1,890
Tdark 3 | 7,003
Tclin 1 | 602

IMPC Term

abnormal QRS complex 2 | 25
abnormal lens morphology 2 | 73
abnormal sleep behavior 2 | 63
decreased lean body mass 2 | 195
decreased mean corpuscular hem... 2 | 19
decreased threshold for audito... 2 | 32
abnormal behavioral response t... 1 | 52
abnormal coat/hair pigmentatio... 1 | 54
abnormal coping response 1 | 12
abnormal eye morphology 1 | 38
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 2
abnormal retina morphology 1 | 100
abnormal retinal vasculature m... 1 | 15
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cataract 1 | 26
convulsive seizures 1 | 11
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating bilirubi... 1 | 14
decreased circulating iron lev... 1 | 25
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased total body fat amoun... 1 | 186
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased bone mineral density 1 | 52
increased circulating insulin ... 1 | 2
increased fasted circulating g... 1 | 68
increased lean body mass 1 | 107
increased red blood cell distr... 1 | 21
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
premature death 1 | 5
preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 35 | 8,484
osteosarcoma 29 | 7,933
psoriasis 29 | 6,685
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,289
lung cancer 21 | 4,466
medulloblastoma, large-cell 21 | 6,234
pancreatic cancer 21 | 2,300
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,988
malignant mesothelioma 20 | 3,162
glioblastoma 19 | 5,572
lung adenocarcinoma 18 | 2,713
non-small cell lung cancer 18 | 2,798
Breast cancer 16 | 3,094
cystic fibrosis 16 | 1,665
lung carcinoma 16 | 2,844
ulcerative colitis 16 | 2,087
Cancer 14 | 2,346
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,795
primitive neuroectodermal tumor 13 | 3,031
atypical teratoid / rhabdoid tumor 12 | 4,369
interstitial cystitis 12 | 2,299
pilocytic astrocytoma 12 | 3,086
primary pancreatic ductal adenocarcinoma 12 | 1,271
astrocytic glioma 11 | 2,241
atypical teratoid/rhabdoid tumor 11 | 1,095
invasive ductal carcinoma 11 | 2,950
tuberculosis 11 | 1,557
Down syndrome 10 | 548
Menkes disease 10 | 20
Pick disease 10 | 1,893
adrenocortical carcinoma 10 | 1,427
breast carcinoma 10 | 1,614
colon cancer 10 | 1,475
oligodendroglioma 10 | 2,849
pediatric high grade glioma 10 | 2,712
Alzheimer's disease 9 | 644
ependymoma 9 | 2,514
group 3 medulloblastoma 9 | 2,254
pituitary cancer 9 | 1,972
Atopic dermatitis 8 | 944
Hepatitis, Chronic 8 | 22
diabetes mellitus 8 | 1,663
ductal carcinoma in situ 8 | 1,745
esophageal adenocarcinoma 8 | 737
posterior fossa group A ependymoma 8 | 1,511
subependymal giant cell astrocytoma 8 | 2,287
Endometriosis 7 | 535
Liver Cirrhosis 7 | 101
Neurodegenerative disease 7 | 383
Wilson disease 7 | 16
active Crohn's disease 7 | 918
adult high grade glioma 7 | 2,148
cutaneous lupus erythematosus 7 | 1,056
gastric carcinoma 7 | 832
sonic hedgehog group medulloblastoma 7 | 1,482
Atherosclerosis 6 | 275
Hypertensive disease 6 | 193
acute quadriplegic myopathy 6 | 1,157
mucosa-associated lymphoid tissue lymphoma 6 | 480
Brain disease 5 | 83
Carcinoma 5 | 2,147
Dementia 5 | 129
Hepatitis 5 | 61
Hepatolenticular Degeneration 5 | 24
Liver Neoplasms, Experimental 5 | 48
Mammary Neoplasms 5 | 410
Multiple myeloma 5 | 1,327
Necrosis 5 | 51
Parkinson's disease 5 | 364
Rheumatoid Arthritis 5 | 1,160
acute myeloid leukemia 5 | 780
interstitial lung disease 5 | 291
juvenile dermatomyositis 5 | 1,189
pancreatic carcinoma 5 | 567
urothelial carcinoma 5 | 318
Anemia 4 | 252
Bladder Neoplasm 4 | 109
Brain Diseases 4 | 22
Cytochrome-c Oxidase Deficiency 4 | 15
Duchenne muscular dystrophy 4 | 602
Hepatitis B 4 | 103
Hepatitis C 4 | 90
Leigh disease 4 | 81
Liver Cirrhosis, Experimental 4 | 108
Liver carcinoma 4 | 217
Liver diseases 4 | 66
Nerve Degeneration 4 | 73
Obesity 4 | 616
Parkinson Disease 4 | 102
Toxic encephalopathy 4 | 131
Vascular disease 4 | 281
astrocytoma 4 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
cytochrome-c oxidase deficiency disease 4 | 14
group 4 medulloblastoma 4 | 1,875
inflammatory breast cancer 4 | 404
medulloblastoma 4 | 1,524
nephrosclerosis 4 | 329
non primary Sjogren syndrome sicca 4 | 840

Tissue

Cardiovascular System 63 | 17,958
Digestive Tract 63 | 18,473
Endocrine System 63 | 18,512
Female tissues 63 | 18,647
Nervous System 63 | 18,561
Skin and soft tissues 63 | 18,115
Urinary Tract 63 | 18,444
Liver and Pancreas 62 | 18,136
Male tissues 61 | 17,969
Blood and immune system 60 | 17,995
Respiratory system 60 | 17,484

Target Family

Non-IDG 35 | 11,971
Enzyme 28 | 4,146
Transporter 2 | 473

UniProt Keyword

Copper 65 | 65
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein SCO2 homolog, mitochondrial SCO2 Tbio Non-IDG -2.16453 144.3 98
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.51621 344.5 145
Alpha-fetoprotein AFP Tbio Non-IDG -4.04711 11505.1 1715
Alpha-synuclein SNCA Tchem Non-IDG -3.59982 3997.3 1484
Metallothionein-1G MT1G Tbio Non-IDG -1.33394 21.9 13
Glypican-1 GPC1 Tbio Non-IDG -2.34418 224.6 160
Metalloreductase STEAP2 STEAP2 Tbio Enzyme -1.70084 48.5 131
Cytochrome c oxidase subunit 1 MT-CO1 Tchem Enzyme -3.60748 4179.7 118
Retina-specific copper amine oxidase AOC2 Tchem Enzyme -2.24632 179.3 53
Probable low affinity copper uptake protein 2 SLC31A2 Tbio Transporter -1.68345 53.9 55