Development Level

Tbio 52 | 11,651
Tchem 11 | 1,388
Tdark 2 | 6,593
Tclin 1 | 612

IMPC Phenotype

increased body length 3 | 32
abnormal sleep behavior 2 | 70
decreased body length 2 | 101
decreased hematocrit 2 | 46
decreased lean body mass 2 | 135
decreased mean corpuscular hem... 2 | 31
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal heart left ventricle ... 1 | 16
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cataract 1 | 92
convulsive seizures 1 | 13
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating bilirubi... 1 | 19
decreased circulating iron lev... 1 | 32
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased cardiac muscle contr... 1 | 8
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
premature death 1 | 5
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 35 | 8,520
Carcinoma 32 | 11,493
osteosarcoma 29 | 7,950
psoriasis 29 | 6,694
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
atypical teratoid / rhabdoid tumor 23 | 5,112
malignant mesothelioma 22 | 3,232
Breast cancer 21 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
lung cancer 21 | 4,740
medulloblastoma, large-cell 21 | 6,241
pancreatic cancer 21 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
glioblastoma 19 | 5,792
group 3 medulloblastoma 18 | 4,104
lung adenocarcinoma 18 | 2,716
non-small cell lung cancer 18 | 2,890
cystic fibrosis 16 | 1,696
ependymoma 16 | 4,679
lung carcinoma 16 | 2,843
ulcerative colitis 16 | 1,819
Cancer 14 | 2,499
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Astrocytoma, Pilocytic 13 | 3,081
Autosomal recessive predisposition 13 | 1,442
adult high grade glioma 13 | 3,801
primitive neuroectodermal tumor 13 | 3,035
astrocytic glioma 12 | 2,597
interstitial cystitis 12 | 2,312
primary pancreatic ductal adenocarcinoma 12 | 1,109
tuberculosis 12 | 2,010
invasive ductal carcinoma 11 | 2,951
Depressive disorder 10 | 409
Pick disease 10 | 1,894
adrenocortical carcinoma 10 | 1,428
breast carcinoma 10 | 1,638
colon cancer 10 | 1,478
diabetes mellitus 10 | 1,728
oligodendroglioma 10 | 2,850
Alzheimer's disease 9 | 658
Atopic dermatitis 9 | 952
Down syndrome 9 | 499
Hypertensive disease 9 | 292
Menkes disease 9 | 19
pituitary cancer 9 | 1,972
Dementia 8 | 175
Hepatitis, Chronic 8 | 23
Liver Cirrhosis 8 | 181
Liver Cirrhosis, Experimental 8 | 769
ductal carcinoma in situ 8 | 1,745
esophageal adenocarcinoma 8 | 737
subependymal giant cell astrocytoma 8 | 2,287
Anemia 7 | 365
Endometriosis 7 | 540
Hypertension 7 | 396
Neurodegenerative disease 7 | 414
Toxic encephalopathy 7 | 141
Wilson disease 7 | 16
active Crohn's disease 7 | 922
cutaneous lupus erythematosus 7 | 1,057
Atherosclerosis 6 | 291
Brain Ischemia 6 | 110
Disease Models, Animal 6 | 155
Intellectual disability 6 | 1,016
Mental Depression 6 | 333
Parkinson's disease 6 | 392
Seizures 6 | 596
acute quadriplegic myopathy 6 | 1,158
gastric carcinoma 6 | 807
mucosa-associated lymphoid tissue lymphoma 6 | 484
Brain disease 5 | 96
Breast Neoplasms 5 | 445
Cerebellar Ataxia 5 | 304
Epilepsy 5 | 792
Fatigue 5 | 182
Heart failure 5 | 162
Hepatitis 5 | 67
Hepatolenticular Degeneration 5 | 24
Liver Neoplasms, Experimental 5 | 59
Mammary Neoplasms 5 | 425
Melanoma 5 | 711
Multiple myeloma 5 | 1,332
Muscle Weakness 5 | 170
Necrosis 5 | 53
Osteoporosis 5 | 363
Rheumatoid arthritis 5 | 1,191
Schizophrenia 5 | 1,160
acute myeloid leukemia 5 | 783
interstitial lung disease 5 | 298
juvenile dermatomyositis 5 | 1,187
non primary Sjogren syndrome sicca 5 | 891
pancreatic carcinoma 5 | 562
urothelial carcinoma 5 | 318
Attention deficit hyperactivity disorder 4 | 278
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Duchenne muscular dystrophy 4 | 601
Vascular disease 4 | 319
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
nephrosclerosis 4 | 333
pediatric high grade glioma 4 | 1,064

Tissue

Endocrine System 64 | 18,159
Female tissues 63 | 17,400
Skin and soft tissues 63 | 17,230
Digestive Tract 62 | 17,369
Liver and Pancreas 61 | 16,750
Male tissues 60 | 17,142
Blood and immune system 59 | 16,909
Nervous System 59 | 16,725
Urinary Tract 59 | 16,678
Cardiovascular System 58 | 15,192
Respiratory system 58 | 16,393

Target Family

Non-IDG 36 | 12,091
Enzyme 28 | 4,145
Transporter 2 | 473

UniProt Keyword

Copper 66 | 66
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein-lysine 6-oxidase LOX Tbio Enzyme -3.36257 2227.1 513
Lysyl oxidase homolog 2 LOXL2 Tbio Enzyme -2.24186 173.0 274
Metallothionein-1F MT1F Tbio Non-IDG -1.17171 15.1 11
Alpha-synuclein SNCA Tchem Non-IDG -3.63937 4224.9 1813
Glypican-1 GPC1 Tbio Non-IDG -2.38207 232.3 202
Superoxide dismutase [Cu-Zn] SOD1 Tbio Enzyme -3.30643 1972.1 1103
Ceruloplasmin CP Tbio Non-IDG -2.88089 683.9 251
SPARC SPARC Tbio Non-IDG -3.10194 1136.1 543
Lysyl oxidase homolog 3 LOXL3 Tbio Enzyme -1.24444 16.8 108
Dopamine beta-hydroxylase DBH Tchem Enzyme -2.92000 674.8 416