Development Level

Tbio 4 | 11,651
Tchem 1 | 1,388
Tclin 1 | 612

IMPC Phenotype

abnormal behavior 1 | 298
abnormal gait 1 | 69
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased neutrophil cell numb... 1 | 42
decreased respiratory quotient 1 | 16
hyperactivity 1 | 148
increased circulating alanine ... 1 | 13
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42

Disease

congenital generalized lipodystrophy 6 | 10
Intellectual disability 5 | 1,016
psoriasis 5 | 6,694
Acanthosis Nigricans 4 | 27
Carcinoma 4 | 11,493
Lipodystrophy 4 | 40
adult high grade glioma 4 | 3,801
diabetes mellitus 4 | 1,728
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
lung carcinoma 4 | 2,843
Abnormal pigmentation 3 | 25
Acromegaly 3 | 51
Advanced bone age 3 | 35
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Bone Cysts 3 | 12
Breast cancer 3 | 3,578
Broad feet 3 | 19
Class III malocclusion 3 | 78
Dull intelligence 3 | 645
Familial generalized lipodystrophy 3 | 5
Generalized hirsutism 3 | 36
Growth hormone excess 3 | 14
Hepatomegaly 3 | 285
Hirsutism 3 | 47
Hyperhidrosis disorder 3 | 81
Hyperinsulinism 3 | 133
Hyperplasia of supraorbital margins 3 | 19
Hyperplasia of supraorbital ridge 3 | 19
Hypertriglyceridemia result 3 | 37
Hypertrophic Cardiomyopathy 3 | 117
Hypertrophy of lower jaw 3 | 78
Hypertrophy of supraorbital margins 3 | 19
Hypertrophy of supraorbital ridge 3 | 19
Increased size of mandible 3 | 78
Increased sweating 3 | 81
Insulin Resistance 3 | 72
Large hand 3 | 18
Lipoatrophic Diabetes Mellitus 3 | 5
Lipoatrophy 3 | 19
Liver Failure 3 | 73
Low intelligence 3 | 645
Mandibular hyperplasia 3 | 78
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Poor school performance 3 | 645
Precocious Puberty 3 | 28
Prominent supraorbital ridges 3 | 19
Skeletal muscle hypertrophy 3 | 16
Steatohepatitis 3 | 44
Sweating 3 | 81
atypical teratoid / rhabdoid tumor 3 | 5,112
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
invasive ductal carcinoma 3 | 2,951
mandibular excess (physical finding) 3 | 78
medulloblastoma, large-cell 3 | 6,241
ulcerative colitis 3 | 1,819
Babinski Reflex 2 | 100
Contracture 2 | 96
Contracture of joint 2 | 93
Down syndrome 2 | 499
Dyspnea 2 | 76
Dystonia 2 | 164
Flexion contracture 2 | 93
Flexion contractures of joints 2 | 93
Hyperphagia 2 | 23
Hyperreflexia 2 | 209
Hypertrophy of clitoris 2 | 40
Liver Cirrhosis 2 | 181
Monoparesis - leg 2 | 27
Myoclonus 2 | 74
Pain agnosia 2 | 104
Paraplegia 2 | 74
Polycystic ovary syndrome 2 | 360
Progressive disorder 2 | 142
Schizophrenia 2 | 1,160
Sclerocystic Ovaries 2 | 17
Tall stature 2 | 34
Umbilical hernia 2 | 93
Weakness of lower limb 2 | 27
Weight Gain 2 | 100
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
fibroadenoma 2 | 559
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
ovarian cancer 2 | 8,520
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 6 | 16,909
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Skin and soft tissues 6 | 17,230
Cardiovascular System 5 | 15,192
Female tissues 5 | 17,400
Respiratory system 5 | 16,393
Urinary Tract 4 | 16,678

Target Family

Enzyme 2 | 4,145
Ion Channel 2 | 344
Non-IDG 2 | 12,091

UniProt Keyword

Congenital generalized lipodys... 6 | 6
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G protein-activated inward rectifier potassium channel 2 KCNJ6 Tbio Ion Channel -2.28200 194.3 215
1-acyl-sn-glycerol-3-phosphate acyltransferase beta AGPAT2 Tchem Enzyme -1.95996 90.8 127
Caveolae-associated protein 1 CAVIN1 Tbio Enzyme -1.97373 101.8 169
Caveolin-1 CAV1 Tbio Non-IDG -3.35685 2432.3 855
Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B Tclin Ion Channel -2.24422 170.7 75
Seipin BSCL2 Tbio Non-IDG -2.35339 244.3 151