Development Level

Tbio 27 | 11,445
Tclin 2 | 613
Tchem 1 | 1,598

IMPC Phenotype

increased circulating sodium l... 2 | 71
abnormal joint morphology 1 | 23
abnormal tibia morphology 1 | 14
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased circulating glucose ... 1 | 126
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
hypoactivity 1 | 132
increased aggression 1 | 4
increased blood urea nitrogen ... 1 | 48
shortened RR interval 1 | 17
thrombocytopenia 1 | 56

Disease

Carcinoma 21 | 11,493
ovarian cancer 19 | 8,520
lung cancer 18 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
lung carcinoma 17 | 2,843
non-small cell lung cancer 15 | 2,890
Autosomal recessive predisposition 13 | 1,442
glioblastoma 13 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
invasive ductal carcinoma 12 | 2,951
lung adenocarcinoma 12 | 2,716
malignant mesothelioma 12 | 3,232
psoriasis 12 | 6,694
ulcerative colitis 11 | 1,819
Astrocytoma, Pilocytic 10 | 3,081
Complement deficiency 10 | 14
Systemic lupus erythematosus 10 | 194
adrenocortical carcinoma 10 | 1,428
interstitial cystitis 10 | 2,312
subependymal giant cell astrocytoma 10 | 2,287
tuberculosis 10 | 2,010
acute quadriplegic myopathy 9 | 1,158
dermatomyositis 9 | 966
Meningitis 8 | 67
cystic fibrosis 8 | 1,696
juvenile dermatomyositis 8 | 1,187
limb girdle muscular dystrophy 2A 8 | 213
medulloblastoma, large-cell 8 | 6,241
pancreatic cancer 8 | 2,398
pituitary cancer 8 | 1,972
Cancer 7 | 2,499
Duchenne muscular dystrophy 7 | 601
Immunologic Deficiency Syndromes 7 | 113
Kidney disease 7 | 430
Lupus Erythematosus, Systemic 7 | 67
Melanoma 7 | 711
Rheumatoid arthritis 7 | 1,191
Skin cancer 7 | 469
ependymoma 7 | 4,679
primary Sjogren syndrome 7 | 735
Age related macular degeneration 6 | 72
Breast cancer 6 | 3,578
Kidney cancer 6 | 2,613
Schizophrenia 6 | 1,160
Vascular disease 6 | 319
adult high grade glioma 6 | 3,801
atypical teratoid / rhabdoid tumor 6 | 5,112
colon cancer 6 | 1,478
esophageal adenocarcinoma 6 | 737
gastric carcinoma 6 | 807
group 3 medulloblastoma 6 | 4,104
nasopharyngeal carcinoma 6 | 1,058
osteosarcoma 6 | 7,950
Anemia 5 | 365
Autoimmune Diseases 5 | 67
Becker muscular dystrophy 5 | 191
Liver Cirrhosis, Experimental 5 | 769
Macular degeneration 5 | 65
active ulcerative colitis 5 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
chronic kidney disease 5 | 90
diabetes mellitus 5 | 1,728
head and neck cancer and chronic obstructive pulmonary disease 5 | 239
Angioedema 4 | 38
Atopic dermatitis 4 | 952
Complement deficiency disease 4 | 6
Decreased serum complement factor I 4 | 4
Down syndrome 4 | 499
Hemolytic-Uremic Syndrome 4 | 30
Lupus erythematosus 4 | 57
Recurrent infections 4 | 48
active Crohn's disease 4 | 922
astrocytic glioma 4 | 2,597
astrocytoma 4 | 1,146
group 4 medulloblastoma 4 | 1,855
periodontitis 4 | 293
Arthritis 3 | 290
Atypical Hemolytic Uremic Syndrome 3 | 9
C1q DEFICIENCY 3 | 3
Chemical and Drug Induced Liver Injury 3 | 195
Congenital afibrinogenemia 3 | 11
Glomerulonephritis, IGA 3 | 34
IGA Glomerulonephritis 3 | 50
Increased susceptibility to Neisseria meningitidis infections 3 | 4
Liver cancer 3 | 604
Multiple Sclerosis 3 | 540
Thrombocytopenia 3 | 197
Type 1 diabetes mellitus 3 | 109
Waldenstrons macroglobulinemia 3 | 765
aldosterone-producing adenoma 3 | 665
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035
sonic hedgehog group medulloblastoma 3 | 467
Gingival Hyperplasia 2 | 34
Gingival Hypertrophy 2 | 34
Gingival Overgrowth 2 | 36

Tissue

Liver and Pancreas 30 | 16,750
Urinary Tract 29 | 16,678
Endocrine System 28 | 18,159
Blood and immune system 27 | 16,909
Digestive Tract 27 | 17,369
Female tissues 27 | 17,400
Male tissues 27 | 17,142
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Cardiovascular System 25 | 15,192
Nervous System 24 | 16,725

Target Family

Non-IDG 27 | 12,091
Enzyme 3 | 4,145

UniProt Keyword

Complement pathway 30 | 30
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Complement C1q subcomponent subunit A C1QA Tbio Non-IDG -1.73823 51.2 241
Complement component 1 Q subcomponent-binding protein, mitochondrial C1QBP Tbio Non-IDG -2.55046 348.6 353
Membrane cofactor protein CD46 Tbio Non-IDG -2.94025 875.6 770
Complement C1r subcomponent-like protein C1RL Tbio Enzyme -0.57210 4.61 83
Complement receptor type 1 CR1 Tbio Non-IDG -3.36509 2362.6 700
Complement receptor type 2 CR2 Tbio Non-IDG -2.97911 940.3 934
Mannan-binding lectin serine protease 2 MASP2 Tbio Enzyme -2.24966 184.0 195
Complement C4-B C4B Tbio Non-IDG -2.99381 1011.9 185
Complement C4-A C4B Tbio Non-IDG -3.04538 1109.8 297
Complement C3 C3 Tbio Non-IDG -3.55963 3446.1 1079