Development Level

Tbio 9 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613

IMPC Phenotype

increased circulating sodium l... 2 | 71
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased circulating alanine ... 1 | 13
increased circulating potassiu... 1 | 29
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased vertical activity 1 | 24
shortened PQ interval 1 | 7
shortened RR interval 1 | 17

Disease

Carcinoma 10 | 11,493
lung cancer 8 | 4,740
non-small cell lung cancer 8 | 2,890
ovarian cancer 8 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Autosomal recessive predisposition 7 | 1,442
Immunologic Deficiency Syndromes 7 | 113
psoriasis 7 | 6,694
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung adenocarcinoma 6 | 2,716
lung carcinoma 6 | 2,843
Complement deficiency 5 | 14
Meningitis 5 | 67
Skin cancer 5 | 469
adrenocortical carcinoma 5 | 1,428
colon cancer 5 | 1,478
invasive ductal carcinoma 5 | 2,951
malignant mesothelioma 5 | 3,232
Age related macular degeneration 4 | 72
Astrocytoma, Pilocytic 4 | 3,081
Duchenne muscular dystrophy 4 | 601
Kidney cancer 4 | 2,613
Kidney disease 4 | 430
Liver Cirrhosis, Experimental 4 | 769
Macular degeneration 4 | 65
Melanoma 4 | 711
Anemia 3 | 365
Atopic dermatitis 3 | 952
Atypical Hemolytic Uremic Syndrome 3 | 9
Complement deficiency disease 3 | 6
Hemolytic-Uremic Syndrome 3 | 30
Increased susceptibility to bacterial infections 3 | 42
Neisseriaceae Infections 3 | 3
Prone to bacterial infection 3 | 42
Recurrent bacterial infection 3 | 42
Rheumatoid arthritis 3 | 1,191
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
diabetes mellitus 3 | 1,728
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
limb girdle muscular dystrophy 2A 3 | 213
osteosarcoma 3 | 7,950
tuberculosis 3 | 2,010
Becker muscular dystrophy 2 | 191
C8 deficiency 2 | 2
Cancer 2 | 2,499
Increased susceptibility to Neisseria meningitidis infections 2 | 4
Kuhnt-Junius degeneration 2 | 14
Liver cancer 2 | 604
Lupus Erythematosus, Systemic 2 | 67
Meningitis, Meningococcal 2 | 3
Meningococcal Infections 2 | 4
Meningococcal meningitis 2 | 8
Myasthenia gravis 2 | 23
Paroxysmal nocturnal hemoglobinuria 2 | 10
Peritonitis 2 | 43
Pneumonia 2 | 174
Systemic lupus erythematosus 2 | 194
Thrombocytopenia 2 | 197
atypical teratoid / rhabdoid tumor 2 | 5,112
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
chronic lymphosyte leukemia 2 | 204
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
fibroadenoma 2 | 559
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
medulloblastoma, large-cell 2 | 6,241
mucosa-associated lymphoid tissue lymphoma 2 | 484
non diabetic and post-ischemic heart failure 2 | 200
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
Alopecia areata 1 | 41
Ascariasis 1 | 7
Chronic Kidney Diseases 1 | 13
Congenital afibrinogenemia 1 | 11
Doyne honeycomb retinal dystrophy 1 | 9
Gaucher disease type 3 1 | 67
Glomerulonephritis 1 | 46
Hematuria 1 | 36
Henoch-Schoenlein purpura 1 | 12
Hypermobility syndrome 1 | 17
Infarction, Middle Cerebral Artery 1 | 33
Keratoconjunctivitis sicca 1 | 25
Lyme disease 1 | 26
Macular Degeneration, Age-Related, 1 1 | 9
Nephrotic Syndrome 1 | 78
Ovarian Cysts 1 | 41
Ovarian serous cystadenocarcinoma 1 | 5
Progressive renal failure 1 | 13
Pulmonary Fibrosis 1 | 106
Salpingitis 1 | 6
Tetanus 1 | 68
Thickening of glomerular basement membrane 1 | 7
Type 1 diabetes mellitus 1 | 109

Tissue

Liver and Pancreas 12 | 16,750
Urinary Tract 12 | 16,678
Endocrine System 11 | 18,159
Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Female tissues 10 | 17,400
Male tissues 10 | 17,142
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Cardiovascular System 9 | 15,192
Nervous System 9 | 16,725

Target Family

Non-IDG 11 | 12,091
Enzyme 1 | 4,145

UniProt Keyword

Complement alternate pathway 12 | 12
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Complement factor D CFD Tchem Enzyme -2.41491 244.6 226
Complement C3 C3 Tbio Non-IDG -3.55963 3446.1 1079
Complement C5 C5 Tclin Non-IDG -2.26690 170.8 448
Complement component C9 C9 Tbio Non-IDG -1.88910 74.6 285
Properdin CFP Tbio Non-IDG -3.18478 1522.9 371
Complement factor H CFH Tbio Non-IDG -3.15872 1420.9 593
Complement factor B CFB Tchem Non-IDG -2.85144 694.6 495
Complement component C7 C7 Tbio Non-IDG -1.39617 24.3 164
Complement component C8 beta chain C8B Tbio Non-IDG -1.57123 37.0 104
Complement component C8 alpha chain C8A Tbio Non-IDG -1.72118 49.8 10