Development Level

Tchem 13 | 1,598
Tbio 5 | 11,445

IMPC Phenotype

abnormal behavior 1 | 298
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal skin coloration 1 | 25
abnormal tail morphology 1 | 25
decreased T cell number 1 | 15
decreased circulating aspartat... 1 | 34
decreased circulating free fat... 1 | 31
decreased circulating triglyce... 1 | 79
hyperactivity 1 | 148
hypoactivity 1 | 132
increased CD4-positive, CD25-p... 1 | 1
increased KLRG1-positive NK ce... 1 | 1
increased NK cell number 1 | 3
increased anti-nuclear antigen... 1 | 19
increased effector memory CD4-... 1 | 1
short tibia 1 | 97

Disease

Carcinoma 15 | 11,493
Cancer 14 | 2,499
non-small cell lung cancer 9 | 2,890
osteosarcoma 9 | 7,950
cystic fibrosis 8 | 1,696
psoriasis 8 | 6,694
ulcerative colitis 8 | 1,819
lung adenocarcinoma 7 | 2,716
malignant mesothelioma 7 | 3,232
ovarian cancer 7 | 8,520
Breast cancer 6 | 3,578
glioblastoma 6 | 5,792
pancreatic cancer 6 | 2,398
periodontitis 6 | 293
Arthritis 5 | 290
Autosomal recessive predisposition 5 | 1,442
Bipolar Disorder 5 | 666
Degenerative disc disease 5 | 35
Liver Cirrhosis, Experimental 5 | 769
Rheumatoid arthritis 5 | 1,191
atypical teratoid / rhabdoid tumor 5 | 5,112
cutaneous lupus erythematosus 5 | 1,057
ductal carcinoma in situ 5 | 1,745
head and neck cancer and chronic obstructive pulmonary disease 5 | 239
interstitial cystitis 5 | 2,312
invasive ductal carcinoma 5 | 2,951
Abortion, Spontaneous 4 | 109
Astrocytoma, Pilocytic 4 | 3,081
Atopic dermatitis 4 | 952
Breast Neoplasms 4 | 445
Dental caries 4 | 164
Endometriosis 4 | 540
Lung disease 4 | 142
Mammary Neoplasms 4 | 425
Neoplasm Invasiveness 4 | 161
Neoplasm Metastasis 4 | 168
Short stature 4 | 531
Spontaneous abortion 4 | 113
Synovitis 4 | 78
Vascular disease 4 | 319
adult high grade glioma 4 | 3,801
breast carcinoma 4 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
nasopharyngeal carcinoma 4 | 1,058
primary pancreatic ductal adenocarcinoma 4 | 1,109
tuberculosis 4 | 2,010
Acquired metabolic disease 3 | 336
Aortic aneurysm 3 | 38
Asthma 3 | 385
Atherosclerosis 3 | 291
Carcinoma, Non-Small-Cell Lung 3 | 107
Cerebral Hemorrhage 3 | 42
Cerebrovascular disease 3 | 238
Chronic Obstructive Airway Disease 3 | 37
Coronary artery disease 3 | 268
Exophthalmos 3 | 112
Generalized osteopenia 3 | 99
Heart disease 3 | 306
Hypertension 3 | 396
Hypoplastic mandible condyle 3 | 275
Kidney cancer 3 | 2,613
Kidney disease 3 | 430
Mandibular hypoplasia 3 | 275
Metaphyseal widening 3 | 22
Micrognathism 3 | 275
Oral Submucous Fibrosis 3 | 20
Osteopenia 3 | 99
Osteoporosis 3 | 363
Pulmonary Fibrosis 3 | 106
Rotting teeth 3 | 73
Schizophrenia 3 | 1,160
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
interstitial lung disease 3 | 298
non-small cell lung carcinoma 3 | 317
Alcoholic Intoxication, Chronic 2 | 289
Alzheimer's disease 2 | 658
Brain Ischemia 2 | 110
Carcinoma, Hepatocellular 2 | 228
Colonic Neoplasms 2 | 142
Dermatitis, Contact 2 | 71
Eye disease 2 | 62
Gingival Hyperplasia 2 | 34
Gingival Hypertrophy 2 | 34
Gingival Overgrowth 2 | 36
Hypersensitivity reaction type II disease 2 | 253
Inflammatory bowel disease 2 | 151
Liver carcinoma 2 | 240
Lung Neoplasms 2 | 232
Multiple Sclerosis 2 | 540
Stomach Neoplasms 2 | 300

Tissue

Female tissues 18 | 17,400
Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Male tissues 16 | 17,142
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Endocrine System 15 | 18,159
Liver and Pancreas 15 | 16,750
Nervous System 14 | 16,725
Cardiovascular System 12 | 15,192

Target Family

Enzyme 15 | 4,145
Non-IDG 3 | 12,091

UniProt Keyword

Collagen degradation 18 | 18
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
A disintegrin and metalloproteinase with thrombospondin motifs 14 ADAMTS14 Tbio Enzyme -0.89572 7.58 29
Disintegrin and metalloproteinase domain-containing protein 15 ADAM15 Tbio Enzyme -1.87408 84.1 301
Stromelysin-3 MMP11 Tchem Non-IDG -2.72089 515.7 385
Matrix metalloproteinase-16 MMP16 Tchem Enzyme -1.80934 59.5 301
Matrix metalloproteinase-27 MMP27 Tbio Enzyme -0.45918 3.10 111
Xaa-Pro dipeptidase PEPD Tchem Enzyme -2.97538 963.8 157
Neutrophil collagenase MMP8 Tchem Enzyme -3.40955 2433.7 483
Myeloblastin PRTN3 Tchem Enzyme -3.46597 2968.8 397
Matrix metalloproteinase-9 MMP9 Tchem Enzyme -3.96102 8811.6 1442
Interstitial collagenase MMP1 Tchem Enzyme -3.44510 2656.8 851