Development Level

Tbio 194 | 10,625
Tchem 62 | 1,890
Tdark 30 | 7,003
Tclin 10 | 602

IMPC Phenotype

preweaning lethality, complete... 11 | 633
preweaning lethality, incomple... 7 | 260
abnormal behavior 4 | 226
decreased circulating glucose ... 4 | 121
decreased vertical activity 4 | 22
enlarged heart 4 | 111
hyperactivity 4 | 108
abnormal bone structure 3 | 131
abnormal heart morphology 3 | 51
abnormal vibrissa morphology 3 | 17
decreased bone mineral content 3 | 157
hypoactivity 3 | 89
increased circulating sodium l... 3 | 71
abnormal QRS complex 2 | 25
abnormal bone mineralization 2 | 55
abnormal eye morphology 2 | 38
abnormal kidney morphology 2 | 30
abnormal seminal vesicle morph... 2 | 47
abnormal sleep behavior 2 | 63
decreased B cell number 2 | 30
decreased circulating triglyce... 2 | 83
decreased eosinophil cell numb... 2 | 41
decreased grip strength 2 | 123
decreased lean body mass 2 | 195
decreased monocyte cell number 2 | 28
improved glucose tolerance 2 | 56
increased body weight 2 | 42
increased bone mineral density 2 | 52
increased fasted circulating g... 2 | 68
increased heart weight 2 | 37
increased mean corpuscular vol... 2 | 91
increased startle reflex 2 | 38
oligodactyly 2 | 14
short tibia 2 | 82
thrombocytopenia 2 | 46
abnormal body wall morphology 1 | 7
abnormal coat appearance 1 | 25
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal duodenum morphology 1 | 1
abnormal embryo size 1 | 112
abnormal facial morphology 1 | 9
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 73
abnormal limb bud morphology 1 | 15
abnormal lung morphology 1 | 15
abnormal lymph node morphology 1 | 3
abnormal neural tube closure 1 | 37
abnormal retinal pigmentation 1 | 61
abnormal snout morphology 1 | 18
abnormal tail morphology 1 | 17
abnormal testis morphology 1 | 30
abnormal tooth morphology 1 | 24
abnormal whole-body plethysmog... 1 | 4
absent lymph nodes 1 | 3
cataract 1 | 26
cleft palate 1 | 6
convulsive seizures 1 | 11
corneal opacity 1 | 25
corneal vascularization 1 | 5
decreased CD11b-low dendritic ... 1 | 3
decreased CD4-positive, CD25-p... 1 | 24
decreased IgG1 level 1 | 4
decreased T cell number 1 | 31
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased threshold for audito... 1 | 32
embryonic growth retardation 1 | 28
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
hemorrhage 1 | 12
hydrometra 1 | 13
hydrops fetalis 1 | 22
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased blood uric acid leve... 1 | 5
increased body length 1 | 20
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating serum al... 1 | 25
increased circulating thyroxin... 1 | 7
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
narrow eye opening 1 | 15
prolonged PR interval 1 | 4
small testis 1 | 37
tremors 1 | 34
vertebral fusion 1 | 23

Disease

psoriasis 117 | 6,685
Cancer 101 | 2,346
ovarian cancer 97 | 8,491
osteosarcoma 92 | 7,933
glioblastoma 85 | 5,572
medulloblastoma, large-cell 84 | 6,234
lung cancer 81 | 4,473
pilocytic astrocytoma 74 | 3,086
lung carcinoma 69 | 2,844
atypical teratoid / rhabdoid tumor 68 | 4,369
malignant mesothelioma 65 | 3,163
diabetes mellitus 63 | 1,663
Breast cancer 60 | 3,098
intraductal papillary-mucinous neoplasm (IPMN) 56 | 3,289
oligodendroglioma 56 | 2,849
Carcinoma 55 | 2,147
interstitial cystitis 53 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 53 | 2,956
lung adenocarcinoma 53 | 2,714
pediatric high grade glioma 53 | 2,712
non-small cell lung cancer 51 | 2,798
Obesity 50 | 616
pancreatic cancer 48 | 2,300
cystic fibrosis 47 | 1,670
group 4 medulloblastoma 47 | 1,875
invasive ductal carcinoma 47 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 45 | 2,988
ulcerative colitis 43 | 2,087
primitive neuroectodermal tumor 41 | 3,031
breast carcinoma 38 | 1,614
colon cancer 38 | 1,475
ependymoma 38 | 2,514
Kidney disease 37 | 397
ductal carcinoma in situ 37 | 1,745
posterior fossa group A ependymoma 35 | 1,511
Hypertension 34 | 293
astrocytic glioma 33 | 2,241
pituitary cancer 33 | 1,972
Alzheimer's disease 31 | 644
adult high grade glioma 31 | 2,148
group 3 medulloblastoma 29 | 2,254
posterior fossa group B ependymoma 29 | 1,530
Atherosclerosis 26 | 275
primary pancreatic ductal adenocarcinoma 26 | 1,271
subependymal giant cell astrocytoma 26 | 2,287
Cerebrovascular disease 25 | 231
adrenocortical carcinoma 25 | 1,427
astrocytoma 25 | 1,493
Coronary artery disease 24 | 240
Diarrhea 24 | 155
Pick disease 24 | 1,893
Hypertensive disease 23 | 193
tuberculosis 23 | 1,563
Arthritis 22 | 248
Down syndrome 22 | 548
sonic hedgehog group medulloblastoma 22 | 1,482
Adenoma 21 | 165
Heart disease 21 | 279
Asthma 20 | 349
Atopic dermatitis 20 | 944
Hypoglycemia 20 | 81
Rheumatoid Arthritis 20 | 1,170
atypical teratoid/rhabdoid tumor 20 | 1,095
fibroadenoma 20 | 557
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,795
Schizophrenia 19 | 503
medulloblastoma 19 | 1,524
Autistic Disorder 18 | 320
Hypotension 18 | 53
Pain agnosia 18 | 99
gastric carcinoma 18 | 832
Anemia 17 | 252
Hypothyroidism 17 | 89
Multiple Sclerosis 17 | 498
Osteoporosis 17 | 259
Vascular disease 17 | 281
cutaneous lupus erythematosus 17 | 1,056
juvenile dermatomyositis 17 | 1,189
esophageal adenocarcinoma 16 | 737
nasopharyngeal carcinoma 16 | 1,056
Cushing's syndrome 15 | 47
Hyperalgesia 15 | 71
Liver disease 15 | 219
Mammary Neoplasms 15 | 410
Parkinson's disease 15 | 364
Duchenne muscular dystrophy 14 | 602
Heart failure 14 | 80
Hyperglycemia 14 | 120
Lung disease 14 | 136
Pain 14 | 70
Pancreatitis 14 | 97
Polycystic Ovary Syndrome 14 | 334
Prostatic Neoplasms 14 | 471
active Crohn's disease 14 | 918
spina bifida 14 | 1,064
Epilepsy 13 | 346
Infertility 13 | 163
Seizures 13 | 95
aldosterone-producing adenoma 13 | 664
periodontitis 13 | 269

Tissue

Endocrine System 274 | 18,511
Female tissues 273 | 18,646
Nervous System 270 | 18,560
Digestive Tract 267 | 18,472
Urinary Tract 267 | 18,443
Skin and soft tissues 265 | 18,114
Liver and Pancreas 263 | 18,135
Blood and immune system 260 | 17,994
Cardiovascular System 258 | 17,957
Male tissues 258 | 17,968
Respiratory system 251 | 17,483

Target Family

Non-IDG 225 | 11,969
Enzyme 66 | 4,146
Kinase 4 | 634
Transcription Factor 1 | 1,400

UniProt Keyword

Cleavage on pair of basic resi... 296 | 296
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine-threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Spexin SPX Tbio Non-IDG -2.76281 568.1 18
Insulin-like peptide INSL6 INSL6 Tdark Non-IDG -1.08799 12.2 31
Complement C3 C3 Tbio Non-IDG -3.54548 3337.1 965
Complement C5 C5 Tclin Non-IDG -2.22372 154.9 317
Progonadoliberin-2 GNRH2 Tbio Non-IDG -2.47841 276.8 104
Endogenous retrovirus group K member 18 Env polyprotein ERVK-18 Tdark Non-IDG 0.00000 0
Nodal homolog NODAL Tbio Non-IDG -2.98097 930.3 232
Carboxypeptidase E CPE Tbio Enzyme -2.99888 983.1 216
Histatin-3 HTN3 Tbio Non-IDG -2.65588 410.6 7
Progonadoliberin-1 GNRH1 Tbio Non-IDG -3.57398 3724.8 253