Development Level

Tbio 112 | 10,625
Tdark 31 | 7,003
Tchem 5 | 1,890

Collection

Eligible Kinase Proteins 3 | 134

IMPC Term

preweaning lethality, complete... 8 | 633
embryonic lethality prior to t... 5 | 187
increased circulating HDL chol... 4 | 63
increased circulating choleste... 4 | 53
increased mean corpuscular hem... 3 | 93
male infertility 3 | 62
abnormal behavior 2 | 226
abnormal testis morphology 2 | 30
decreased circulating glucose ... 2 | 121
embryonic lethality prior to o... 2 | 148
hypoactivity 2 | 89
increased body weight 2 | 42
increased circulating chloride... 2 | 43
increased fasted circulating g... 2 | 68
increased mean corpuscular vol... 2 | 91
preweaning lethality, incomple... 2 | 260
short tibia 2 | 82
small testis 2 | 37
abnormal behavioral response t... 1 | 52
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal eyelid aperture 1 | 3
abnormal gait 1 | 51
abnormal humerus morphology 1 | 11
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal nail morphology 1 | 7
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal seminal vesicle morph... 1 | 47
abnormal startle reflex 1 | 14
cardiovascular system phenotyp... 1 | 35
convulsive seizures 1 | 11
decreased CD4-positive, alpha ... 1 | 19
decreased Ly6C low monocyte nu... 1 | 23
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating bilirubi... 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased coping response 1 | 5
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased follicular B cell nu... 1 | 4
decreased grip strength 1 | 123
decreased heart rate variabili... 1 | 11
decreased lactate dehydrogenas... 1 | 14
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased respiratory quotient 1 | 12
embryonic growth retardation 1 | 28
enlarged liver 1 | 3
enlarged uterus 1 | 3
hydrometra 1 | 13
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating LDL chol... 1 | 15
increased circulating alanine ... 1 | 11
increased circulating amylase ... 1 | 13
increased circulating aspartat... 1 | 17
increased circulating glucose ... 1 | 16
increased circulating glycerol... 1 | 11
increased circulating insulin ... 1 | 2
increased grip strength 1 | 83
increased heart rate 1 | 17
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased prepulse inhibition 1 | 21
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
polydactyly 1 | 22
shortened RR interval 1 | 19
small superior vagus ganglion 1 | 20
thrombocytopenia 1 | 46
thrombocytosis 1 | 23

Disease

ovarian cancer 80 | 8,484
osteosarcoma 58 | 7,933
posterior fossa group B ependymoma 58 | 1,530
psoriasis 44 | 6,685
medulloblastoma, large-cell 43 | 6,234
glioblastoma 41 | 5,572
Polydactyly 36 | 93
atypical teratoid / rhabdoid tumor 34 | 4,369
lung cancer 31 | 4,466
Ciliopathy 30 | 57
Carcinoma 27 | 2,147
Nephronophthisis 26 | 74
primitive neuroectodermal tumor 26 | 3,031
Joubert syndrome 25 | 61
astrocytic glioma 25 | 2,241
chronic rhinosinusitis 25 | 512
malignant mesothelioma 25 | 3,162
Breast cancer 24 | 3,094
pediatric high grade glioma 24 | 2,712
nasopharyngeal carcinoma 22 | 1,056
pilocytic astrocytoma 22 | 3,086
lung carcinoma 21 | 2,844
Bardet-Biedl Syndrome 20 | 40
Intellectual disability 20 | 573
Meckel syndrome 20 | 48
ependymoma 20 | 2,514
group 3 medulloblastoma 20 | 2,254
oligodendroglioma 20 | 2,849
Pick disease 19 | 1,893
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,988
Primary ciliary dyskinesia 18 | 73
Retinitis pigmentosa 17 | 153
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,289
Asphyxiating thoracic dystrophy 16 | 32
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
invasive ductal carcinoma 16 | 2,950
lung adenocarcinoma 16 | 2,713
Fundus dystrophy 15 | 77
Obesity 15 | 616
non-small cell lung cancer 15 | 2,798
Senior-Loken syndrome 13 | 21
Situs Inversus 12 | 48
atypical teratoid/rhabdoid tumor 12 | 1,095
group 4 medulloblastoma 12 | 1,875
interstitial cystitis 12 | 2,299
sonic hedgehog group medulloblastoma 12 | 1,482
subependymal giant cell astrocytoma 12 | 2,287
Meckel-Gruber syndrome 11 | 15
Orofaciodigital syndrome 11 | 19
colon cancer 11 | 1,475
medulloblastoma 11 | 1,524
pituitary cancer 11 | 1,972
progressive supranuclear palsy 11 | 674
tuberculosis 11 | 1,557
Cancer 10 | 2,346
adult high grade glioma 10 | 2,148
ulcerative colitis 10 | 2,087
Cone dystrophy 9 | 57
Cystic kidney disease 9 | 25
Hydrocephalus 9 | 60
Kartagener Syndrome 9 | 32
adrenocortical carcinoma 9 | 1,427
cystic fibrosis and chronic rhinosinusitis 9 | 213
pancreatic cancer 9 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
Rheumatoid Arthritis 8 | 1,160
astrocytoma 8 | 1,493
posterior fossa group A ependymoma 8 | 1,511
primary pancreatic ductal adenocarcinoma 8 | 1,271
Sensenbrenner syndrome 7 | 15
acute quadriplegic myopathy 7 | 1,157
ductal carcinoma in situ 7 | 1,745
Coloboma 6 | 51
Familial aplasia of the vermis 6 | 8
Hydrolethalus syndrome 6 | 128
Leber congenital amaurosis 6 | 72
Polycystic kidney disease 6 | 54
Renal dysplasia and retinal aplasia (disorder) 6 | 10
active Crohn's disease 6 | 918
cutaneous lupus erythematosus 6 | 1,056
gastric carcinoma 6 | 832
non primary Sjogren syndrome sicca 6 | 840
tuberculosis and treatment for 6 months 6 | 686
Ellis-Van Creveld syndrome 5 | 18
Endometriosis 5 | 535
breast carcinoma 5 | 1,614
diabetes mellitus 5 | 1,663
Acrofacial dysostosis 4 | 8
Blindness 4 | 84
Cranioectodermal Dysplasia 4 | 4
Jeune thoracic dystrophy 4 | 9
Male infertility 4 | 170
Multiple myeloma 4 | 1,327
OROFACIODIGITAL SYNDROME VI 4 | 6
Retinal Degeneration 4 | 49
Schizophrenia 4 | 501
active ulcerative colitis 4 | 477
dermatomyositis 4 | 933
primary Sjogren syndrome 4 | 789
spina bifida 4 | 1,064

Tissue

Female tissues 148 | 18,647
Male tissues 148 | 17,969
Nervous System 148 | 18,561
Digestive Tract 147 | 18,473
Endocrine System 147 | 18,512
Liver and Pancreas 147 | 18,136
Respiratory system 147 | 17,484
Urinary Tract 147 | 18,444
Blood and immune system 146 | 17,995
Cardiovascular System 146 | 17,958
Skin and soft tissues 145 | 18,115

Target Family

Non-IDG 126 | 11,971
Enzyme 12 | 4,146
Kinase 6 | 634
Transcription Factor 4 | 1,400

UniProt Keyword

Cilium biogenesis/degradation 148 | 148
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Multicilin MCIDAS Tbio Non-IDG -2.00076 101.0 59
Centrosomal protein of 164 kDa CEP164 Tbio Non-IDG -0.96655 10.2 84
Protein C21orf2 C21orf2 Tbio Non-IDG -1.66840 37.4 95
Bardet-Biedl syndrome 7 protein BBS7 Tbio Non-IDG -1.02867 11.1 125
Actin-related protein 3 ACTR3 Tbio Non-IDG -1.25542 16.8 169
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -1.97186 101.3 125
Centrosomal protein of 152 kDa CEP152 Tbio Non-IDG -1.23739 18.0 90
Retinitis pigmentosa 1-like 1 protein RP1L1 Tbio Non-IDG -1.19453 19.3 0
Cilia- and flagella-associated protein 46 CFAP46 Tdark Non-IDG -0.17609 1.50 33
Nephrocystin-1 NPHP1 Tbio Non-IDG -1.70748 50.8 88