Development Level

Tbio 32 | 11,445
Tchem 6 | 1,598
Tdark 6 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal bone structure 2 | 187
abnormal lens morphology 2 | 81
cataract 2 | 92
male infertility 2 | 123
abnormal behavior 1 | 298
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
absent pinna reflex 1 | 23
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
enlarged lymph nodes 1 | 37
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
shortened RR interval 1 | 17
small kidney 1 | 16
small spleen 1 | 19
small testis 1 | 58
vertebral transformation 1 | 12

Disease

ovarian cancer 33 | 8,520
Carcinoma 30 | 11,493
medulloblastoma, large-cell 26 | 6,241
group 3 medulloblastoma 22 | 4,104
lung cancer 21 | 4,740
osteosarcoma 21 | 7,950
glioblastoma 20 | 5,792
psoriasis 20 | 6,694
Cancer 18 | 2,499
Breast cancer 17 | 3,578
primitive neuroectodermal tumor 17 | 3,035
atypical teratoid / rhabdoid tumor 16 | 5,112
ependymoma 16 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
invasive ductal carcinoma 14 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
malignant mesothelioma 12 | 3,232
non-small cell lung cancer 12 | 2,890
Intellectual disability 11 | 1,016
Kidney cancer 11 | 2,613
adult high grade glioma 11 | 3,801
Endometriosis 10 | 540
adrenocortical carcinoma 10 | 1,428
lung adenocarcinoma 10 | 2,716
oligodendroglioma 10 | 2,850
Atopic dermatitis 9 | 952
Multiple myeloma 9 | 1,332
astrocytic glioma 9 | 2,597
ductal carcinoma in situ 9 | 1,745
pancreatic cancer 9 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
Waldenstrons macroglobulinemia 8 | 765
breast carcinoma 8 | 1,638
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Rheumatoid arthritis 6 | 1,191
Short stature 6 | 531
acute quadriplegic myopathy 6 | 1,158
colon cancer 6 | 1,478
dermatomyositis 6 | 966
Astrocytoma, Pilocytic 5 | 3,081
Muscle hypotonia 5 | 571
Small head 5 | 374
group 4 medulloblastoma 5 | 1,855
pediatric high grade glioma 5 | 1,064
Cataract 4 | 297
Cornelia de Lange syndrome 4 | 21
Hypoplastic mandible condyle 4 | 275
Lens Opacities 4 | 231
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
nasopharyngeal carcinoma 4 | 1,058
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819
Abnormally small eyeball 3 | 97
Anteverted nostril 3 | 191
Autosomal recessive predisposition 3 | 1,442
Bladder Neoplasm 3 | 112
Broad flat nasal bridge 3 | 236
Congenital hypoplasia of penis 3 | 176
Cryptorchidism 3 | 296
Decreased size of eyeball 3 | 97
Endometrial cancer 3 | 311
Glaucoma 3 | 239
Leukemia, Megakaryoblastic, of Down Syndrome 3 | 8
Liver Cirrhosis, Experimental 3 | 769
Melanoma 3 | 711
Microphthalmos 3 | 100
Nasal bridge wide 3 | 236
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Sensorineural Hearing Loss (disorder) 3 | 284
Stomach Neoplasms 3 | 300
Urinary Bladder Neoplasms 3 | 114
Xeroderma pigmentosum group D 3 | 33
diabetes mellitus 3 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
pancreatic carcinoma 3 | 562
primary Sjogren syndrome 3 | 735
Bipolar Disorder 2 | 666
Congenital Epicanthus 2 | 177
Contact Dermatitis 2 | 81
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Pediatric failure to thrive 2 | 365
Seizures 2 | 596
Strabismus 2 | 270
Thin lips 2 | 49
astrocytoma 2 | 1,146
esophageal adenocarcinoma 2 | 737
juvenile dermatomyositis 2 | 1,187
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 676
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Blood and immune system 45 | 16,909
Endocrine System 45 | 18,159
Male tissues 45 | 17,142
Digestive Tract 44 | 17,369
Female tissues 44 | 17,400
Nervous System 44 | 16,725
Skin and soft tissues 44 | 17,230
Liver and Pancreas 43 | 16,750
Respiratory system 43 | 16,393
Urinary Tract 43 | 16,678
Cardiovascular System 40 | 15,192

Target Family

Non-IDG 31 | 12,091
Enzyme 7 | 4,145
Kinase 4 | 634
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400
Transporter 1 | 473

UniProt Keyword

Chromosome partition 45 | 45
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Cohesin subunit SA-1 STAG1 Tbio Non-IDG -2.47449 292.2 200
Kinesin-like protein KIF2C KIF2C Tbio Non-IDG -2.12404 136.3 256
Cohesin subunit SA-3 STAG3 Tbio Non-IDG -1.30055 20.0 104
Probable cytosolic iron-sulfur protein assembly protein CIAO1 CIAO1 Tbio Non-IDG -1.44311 25.1 161
Shugoshin 1 SGO1 Tbio Non-IDG -2.44224 279.8 148
Kinetochore scaffold 1 KNL1 Tbio Non-IDG -2.20924 151.8 85
BUB3-interacting and GLEBS motif-containing protein ZNF207 ZNF207 Tbio Non-IDG -0.82146 6.93 264
Double-strand-break repair protein rad21-like protein 1 RAD21L1 Tdark Non-IDG -0.98602 12.1 6
ADP/ATP translocase 2 SLC25A5 Tbio Transporter -1.98936 91.6 65