Development Level

Tbio 255 | 10,625
Tdark 74 | 7,003
Tchem 32 | 1,890

IMPC Term

preweaning lethality, complete... 19 | 633
decreased total body fat amoun... 7 | 186
abnormal retina morphology 5 | 100
embryonic lethality prior to o... 5 | 148
embryonic lethality prior to t... 5 | 187
increased fasted circulating g... 5 | 68
abnormal behavior 4 | 226
decreased body weight 4 | 174
decreased bone mineral content 4 | 157
increased grip strength 4 | 83
preweaning lethality, incomple... 4 | 260
abnormal coat/hair pigmentatio... 3 | 54
decreased body length 3 | 108
decreased bone mineral density 3 | 126
decreased circulating serum al... 3 | 79
decreased lean body mass 3 | 195
hyperactivity 3 | 108
increased bone mineral density 3 | 52
increased lean body mass 3 | 107
male infertility 3 | 62
thrombocytopenia 3 | 46
tremors 3 | 34
abnormal bone structure 2 | 131
abnormal lens morphology 2 | 73
decreased basophil cell number 2 | 11
decreased circulating LDL chol... 2 | 37
decreased circulating alanine ... 2 | 53
decreased circulating chloride... 2 | 32
decreased circulating choleste... 2 | 85
decreased circulating glucose ... 2 | 121
decreased grip strength 2 | 123
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular vol... 2 | 50
decreased rib number 2 | 59
embryonic growth retardation 2 | 28
female infertility 2 | 34
hypoactivity 2 | 89
increased bone mineral content 2 | 92
increased circulating chloride... 2 | 43
increased circulating sodium l... 2 | 71
increased neutrophil cell numb... 2 | 15
increased or absent threshold ... 2 | 128
increased sacral vertebrae num... 2 | 62
short tibia 2 | 82
shortened RR interval 2 | 19
small testis 2 | 37
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal craniofacial morpholo... 1 | 12
abnormal defecation 1 | 1
abnormal embryo size 1 | 112
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal locomotor activation 1 | 26
abnormal optic disc morphology 1 | 10
abnormal placenta morphology 1 | 4
abnormal placenta vasculature 1 | 2
abnormal respiratory quotient 1 | 9
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
abnormal thoracic vertebrae mo... 1 | 16
abnormal vertebrae morphology 1 | 14
abnormal vocalization 1 | 21
cataract 1 | 26
corneal opacity 1 | 25
decreased caudal vertebrae num... 1 | 49
decreased circulating glycerol... 1 | 19
decreased circulating iron lev... 1 | 25
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased lumbar vertebrae num... 1 | 62
enlarged lymph nodes 1 | 27
increased NK T cell number 1 | 11
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating amylase ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating potassiu... 1 | 31
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased effector memory CD4-... 1 | 15
increased gamma-delta T cell n... 1 | 16
increased hematocrit 1 | 36
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased prepulse inhibition 1 | 21
oligodactyly 1 | 14
persistence of hyaloid vascula... 1 | 22
prenatal lethality prior to he... 1 | 64
shortened PQ interval 1 | 6
vertebral fusion 1 | 23

Disease

ovarian cancer 195 | 8,484
osteosarcoma 162 | 7,933
medulloblastoma, large-cell 149 | 6,234
psoriasis 140 | 6,685
glioblastoma 124 | 5,572
lung cancer 124 | 4,466
Breast cancer 111 | 3,094
primitive neuroectodermal tumor 102 | 3,031
atypical teratoid / rhabdoid tumor 94 | 4,369
malignant mesothelioma 88 | 3,162
group 3 medulloblastoma 87 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 87 | 3,289
non-small cell lung cancer 84 | 2,798
lung adenocarcinoma 83 | 2,713
intraductal papillary-mucinous carcinoma (IPMC) 82 | 2,988
pediatric high grade glioma 82 | 2,712
invasive ductal carcinoma 77 | 2,950
Cancer 65 | 2,346
adrenocortical carcinoma 63 | 1,427
Carcinoma 56 | 2,147
oligodendroglioma 55 | 2,849
ductal carcinoma in situ 53 | 1,745
breast carcinoma 49 | 1,614
colon cancer 48 | 1,475
ependymoma 48 | 2,514
pancreatic cancer 46 | 2,300
astrocytic glioma 44 | 2,241
sonic hedgehog group medulloblastoma 41 | 1,482
intraductal papillary-mucinous adenoma (IPMA) 40 | 2,956
nasopharyngeal carcinoma 39 | 1,056
Pick disease 38 | 1,893
pancreatic ductal adenocarcinoma liver metastasis 38 | 1,795
posterior fossa group A ependymoma 36 | 1,511
Multiple myeloma 34 | 1,327
Waldenstrons macroglobulinemia 34 | 765
atypical teratoid/rhabdoid tumor 34 | 1,095
subependymal giant cell astrocytoma 34 | 2,287
Endometriosis 33 | 535
Atopic dermatitis 30 | 944
pilocytic astrocytoma 30 | 3,086
pituitary cancer 29 | 1,972
ulcerative colitis 28 | 2,087
IGA Glomerulonephritis 27 | 454
group 4 medulloblastoma 27 | 1,875
Rheumatoid Arthritis 26 | 1,160
dermatomyositis 26 | 933
acute quadriplegic myopathy 24 | 1,157
adult high grade glioma 24 | 2,148
Intellectual disability 23 | 573
juvenile dermatomyositis 23 | 1,189
diabetes mellitus 22 | 1,663
lung carcinoma 22 | 2,844
medulloblastoma 22 | 1,524
non primary Sjogren syndrome sicca 22 | 840
primary Sjogren syndrome 20 | 789
acute myeloid leukemia 19 | 780
astrocytoma 19 | 1,493
interstitial cystitis 19 | 2,299
progressive supranuclear palsy 18 | 674
cystic fibrosis 17 | 1,665
inflammatory breast cancer 17 | 404
non-small cell lung carcinoma 17 | 413
pancreatic carcinoma 17 | 567
Male infertility 16 | 170
gastric cancer 16 | 430
Infertility 15 | 163
tuberculosis 15 | 1,557
tuberculosis and treatment for 6 months 15 | 686
gastric carcinoma 14 | 832
hepatocellular carcinoma 14 | 532
Microcephaly 13 | 149
cutaneous lupus erythematosus 13 | 1,056
posterior fossa group B ependymoma 13 | 1,530
Down syndrome 12 | 548
Mammary Neoplasms 12 | 410
primary pancreatic ductal adenocarcinoma 12 | 1,271
spina bifida 12 | 1,064
Ataxia telangiectasia 10 | 31
Fanconi's anemia 10 | 50
Roberts syndrome 10 | 16
aldosterone-producing adenoma 10 | 664
Autistic Disorder 9 | 320
Peripheral Neuropathy 9 | 303
active Crohn's disease 9 | 918
Adenoid Cystic Carcinoma 8 | 99
Alzheimer's disease 8 | 644
Amyotrophic Lateral Sclerosis 8 | 431
Nijmegen breakage syndrome 8 | 23
Schizophrenia 8 | 501
esophageal adenocarcinoma 8 | 737
Chronic Lymphocytic Leukemia 7 | 242
Cornelia de Lange syndrome 7 | 21
Lupus erythematosus 7 | 80
Seckel syndrome 7 | 34
Acquired metabolic disease 6 | 267
Melanoma 6 | 261
Prostate cancer 6 | 172
Prostatic Neoplasms 6 | 471
cystic fibrosis and chronic rhinosinusitis 6 | 213
hereditary spastic paraplegia 6 | 313

Tissue

Female tissues 353 | 18,647
Endocrine System 351 | 18,512
Blood and immune system 350 | 17,995
Nervous System 350 | 18,561
Urinary Tract 350 | 18,444
Cardiovascular System 348 | 17,958
Digestive Tract 348 | 18,473
Male tissues 348 | 17,969
Liver and Pancreas 345 | 18,136
Respiratory system 341 | 17,484
Skin and soft tissues 338 | 18,115

Target Family

Non-IDG 257 | 11,971
Enzyme 41 | 4,146
Epigenetic 28 | 242
Transcription Factor 21 | 1,400
Kinase 10 | 634
TF/Epigenetic 4 | 38

UniProt Keyword

Chromosome 361 | 361
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
Histone-lysine N-methyltransferase SETD1B SETD1B Tbio Epigenetic -1.20916 14.6 78
Lymphoid-restricted membrane protein LRMP Tbio Non-IDG -1.17754 15.9 54
Kinetochore protein Nuf2 NUF2 Tbio Non-IDG -1.66072 48.8 98
Centromere protein F CENPF Tbio Non-IDG -1.98596 103.0 180
Histone H3-like centromeric protein A CENPA Tbio Non-IDG -2.68837 532.8 347
Putative high mobility group protein B1-like 1 HMGB1P1 Tdark Non-IDG -3.17050 1948.8 0
Protein ELYS AHCTF1 Tbio Non-IDG -1.30356 22.8 57
Neuroguidin NGDN Tbio Non-IDG -2.18414 121.6 78
Protein Mis18-alpha MIS18A Tdark Non-IDG -2.10690 101.0 41