Development Level

Tbio 33 | 11,651
Tclin 23 | 612
Tchem 12 | 1,388
Tdark 6 | 6,593

Collection

Ion Channel: IDG Consortium (T... 19 | 99
RFA-RM-18-021 18 | 328

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal heart morphology 2 | 162
decreased lymphocyte cell numb... 2 | 83
enlarged heart 2 | 210
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal testis morphology 1 | 43
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
increased circulating iron lev... 1 | 30
increased fasted circulating g... 1 | 76
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 58 | 11,493
psoriasis 34 | 6,694
medulloblastoma, large-cell 30 | 6,241
ependymoma 27 | 4,679
atypical teratoid / rhabdoid tumor 26 | 5,112
glioblastoma 26 | 5,792
lung carcinoma 23 | 2,843
ovarian cancer 23 | 8,520
Epilepsy 22 | 792
adult high grade glioma 22 | 3,801
oligodendroglioma 22 | 2,850
osteosarcoma 22 | 7,950
Astrocytoma, Pilocytic 21 | 3,081
Kidney cancer 21 | 2,613
primitive neuroectodermal tumor 19 | 3,035
General anesthesia 18 | 53
cystic fibrosis 18 | 1,696
lung cancer 17 | 4,740
malignant mesothelioma 17 | 3,232
Anxiety 16 | 136
Insomnia 16 | 20
Tonic-clonic epilepsy 16 | 47
astrocytic glioma 16 | 2,597
group 3 medulloblastoma 16 | 4,104
Breast cancer 15 | 3,578
Schizophrenia 15 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
pancreatic cancer 15 | 2,398
Alcoholic Intoxication, Chronic 14 | 289
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
subependymal giant cell astrocytoma 14 | 2,287
Bipolar Disorder 13 | 666
Sedation as Adjunct to Anesthesia 13 | 15
lung adenocarcinoma 13 | 2,716
Autosomal recessive predisposition 12 | 1,442
Autistic Disorder 11 | 364
Pick disease 10 | 1,894
ductal carcinoma in situ 10 | 1,745
group 4 medulloblastoma 10 | 1,855
invasive ductal carcinoma 10 | 2,951
non primary Sjogren syndrome sicca 10 | 891
pituitary cancer 10 | 1,972
ulcerative colitis 10 | 1,819
Alcohol dependence 9 | 107
Intellectual disability 9 | 1,016
Panic disorder 9 | 61
active Crohn's disease 9 | 922
breast carcinoma 9 | 1,638
non-small cell lung cancer 9 | 2,890
Alcohol withdrawal delirium 8 | 11
Alcohol withdrawal syndrome 8 | 20
Benzodiazepine Induced Sedation 8 | 8
Benzodiazepine Maintained Anesthesia 8 | 8
Benzodiazepine Toxicity 8 | 8
Dull intelligence 8 | 645
Induce Anterograde Amnesia 8 | 9
Local anesthesia 8 | 40
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
Preoperative Anxiety 8 | 9
Sedation 8 | 11
Sedation in Intubated Patients 8 | 8
Spasticity 8 | 26
Status Epilepticus 8 | 98
Tetanus 8 | 68
interstitial cystitis 8 | 2,312
nasopharyngeal carcinoma 8 | 1,058
Anxiety associated with Menopause 7 | 7
Conscious sedation 7 | 10
Dent disease 7 | 18
Feeling agitated 7 | 7
Generalized anxiety disorder 7 | 29
Irritable bowel syndrome 7 | 60
Mixed anxiety and depressive disorder 7 | 12
Nephrolithiasis 7 | 56
Partial Epilepsy Treatment Adjunct 7 | 16
Peptic Ulcer 7 | 27
Pre-Op Apprehension 7 | 10
Severe Insomnia 7 | 7
Severe anxiety (panic) 7 | 7
colon cancer 7 | 1,478
cutaneous lupus erythematosus 7 | 1,057
gastric carcinoma 7 | 807
Initial insomnia 6 | 8
Mood Disorders 6 | 184
Muscle hypotonia 6 | 571
Pain with Tension and Anxiety 6 | 6
Schizoaffective Disorder 6 | 55
Seizures 6 | 596
active ulcerative colitis 6 | 764
Cognitive delay 5 | 608
Mental Depression 5 | 333
Mental and motor retardation 5 | 608
Rheumatoid arthritis 5 | 1,191
diabetes mellitus 5 | 1,728
esophageal adenocarcinoma 5 | 737
primary pancreatic ductal adenocarcinoma 5 | 1,109

Tissue

Endocrine System 72 | 18,159
Digestive Tract 68 | 17,369
Female tissues 68 | 17,400
Skin and soft tissues 68 | 17,230
Nervous System 67 | 16,725
Blood and immune system 66 | 16,909
Male tissues 63 | 17,142
Liver and Pancreas 60 | 16,750
Urinary Tract 58 | 16,678
Respiratory system 54 | 16,393
Cardiovascular System 51 | 15,192

Target Family

Ion Channel 56 | 344
Transporter 8 | 473
Enzyme 5 | 4,145
Non-IDG 3 | 12,091
Kinase 1 | 634
Transcription Factor 1 | 1,400

UniProt Keyword

Chloride 74 | 74
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-amylase 2B AMY2B Tbio Enzyme -2.04365 112.9 137
Protein tweety homolog 3 TTYH3 Tbio Ion Channel -0.17609 1.56 17
Chloride intracellular channel protein 4 CLIC4 Tbio Ion Channel -1.81713 70.5 221
Pancreatic alpha-amylase AMY2A Tclin Enzyme -2.93089 824.2 250
Anoctamin-6 ANO6 Tbio Ion Channel -2.50568 319.2 90
H(+)/Cl(-) exchange transporter 5 CLCN5 Tbio Ion Channel -2.32606 225.3 156
H(+)/Cl(-) exchange transporter 7 CLCN7 Tbio Ion Channel -1.96458 100.7 151
Chloride channel protein ClC-Kb CLCNKB Tchem Ion Channel -1.94166 90.6 96
Cystic fibrosis transmembrane conductance regulator CFTR Tclin Ion Channel -3.79415 6397.4 472
Solute carrier family 12 member 8 SLC12A8 Tbio Transporter -0.88998 8.14 26