Development Level

Tbio 145 | 10,625
Tdark 32 | 7,003
Tchem 19 | 1,890
Tclin 2 | 602

IMPC Phenotype

preweaning lethality, complete... 7 | 633
preweaning lethality, incomple... 7 | 260
decreased circulating glucose ... 4 | 121
abnormal behavioral response t... 3 | 52
decreased body weight 3 | 174
increased grip strength 3 | 83
abnormal lens morphology 2 | 73
abnormal maxilla morphology 2 | 16
decreased anxiety-related resp... 2 | 12
decreased circulating triglyce... 2 | 83
decreased grip strength 2 | 123
decreased lean body mass 2 | 195
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
increased body length 2 | 20
increased circulating HDL chol... 2 | 63
increased fasted circulating g... 2 | 68
increased lean body mass 2 | 107
abnormal behavior 1 | 226
abnormal coat-hair pigmentatio... 1 | 54
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 14
abnormal vitreous body morphol... 1 | 7
cardiovascular system phenotyp... 1 | 35
decreased bone mineral content 1 | 157
decreased caudal vertebrae num... 1 | 49
decreased circulating alanine ... 1 | 53
decreased late germinal center... 1 | 2
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
decreased thoracic vertebrae n... 1 | 7
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
embryonic growth retardation 1 | 28
impaired righting response 1 | 19
increased aggression 1 | 2
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating glucose ... 1 | 16
increased early germinal cente... 1 | 2
increased erythrocyte cell num... 1 | 26
increased heart rate 1 | 17
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased or absent threshold ... 1 | 128
increased prepulse inhibition 1 | 21
increased respiratory quotient 1 | 12
increased startle reflex 1 | 38
increased vertical activity 1 | 18
male infertility 1 | 62
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
shortened QT interval 1 | 4
shortened RR interval 1 | 19
tremors 1 | 34

Disease

ovarian cancer 120 | 8,491
osteosarcoma 78 | 7,933
lung cancer 69 | 4,473
medulloblastoma, large-cell 67 | 6,234
psoriasis 61 | 6,685
glioblastoma 59 | 5,572
atypical teratoid / rhabdoid tumor 50 | 4,369
Multiple myeloma 39 | 1,327
Breast cancer 38 | 3,098
intraductal papillary-mucinous neoplasm (IPMN) 35 | 3,289
non-small cell lung cancer 35 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,795
lung adenocarcinoma 31 | 2,714
invasive ductal carcinoma 30 | 2,950
pediatric high grade glioma 29 | 2,712
malignant mesothelioma 28 | 3,163
subependymal giant cell astrocytoma 28 | 2,287
Cancer 27 | 2,346
oligodendroglioma 27 | 2,849
Waldenstrons macroglobulinemia 25 | 764
acute quadriplegic myopathy 25 | 1,157
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
astrocytic glioma 24 | 2,241
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,988
pancreatic cancer 24 | 2,300
primitive neuroectodermal tumor 24 | 3,031
ependymoma 23 | 2,514
astrocytoma 22 | 1,493
group 3 medulloblastoma 22 | 2,254
pilocytic astrocytoma 22 | 3,086
colon cancer 21 | 1,475
diabetes mellitus 19 | 1,663
juvenile dermatomyositis 18 | 1,189
adult high grade glioma 17 | 2,148
interstitial cystitis 17 | 2,299
lung carcinoma 17 | 2,844
medulloblastoma 17 | 1,524
ulcerative colitis 17 | 2,087
Pick disease 16 | 1,893
dermatomyositis 16 | 966
group 4 medulloblastoma 16 | 1,875
Neurodegenerative disease 15 | 383
acute myeloid leukemia 15 | 785
cystic fibrosis 15 | 1,670
pituitary cancer 15 | 1,972
active Crohn's disease 14 | 918
non primary Sjogren syndrome sicca 14 | 840
posterior fossa group A ependymoma 14 | 1,511
tuberculosis 14 | 1,563
Rheumatoid Arthritis 13 | 1,170
HIV Infections 12 | 99
ductal carcinoma in situ 12 | 1,745
esophageal adenocarcinoma 12 | 737
hepatocellular carcinoma 12 | 550
sonic hedgehog group medulloblastoma 12 | 1,482
adrenocortical carcinoma 11 | 1,427
breast carcinoma 11 | 1,614
tuberculosis and treatment for 6 months 11 | 686
Atopic dermatitis 10 | 944
Parkinson's disease 10 | 364
Prostatic Neoplasms 10 | 471
posterior fossa group B ependymoma 10 | 1,530
Carcinoma 9 | 2,147
Down syndrome 9 | 548
Duchenne muscular dystrophy 9 | 602
atypical teratoid/rhabdoid tumor 9 | 1,095
hereditary spastic paraplegia 9 | 313
pancreatic carcinoma 9 | 567
primary pancreatic ductal adenocarcinoma 9 | 1,271
spina bifida 9 | 1,064
chronic rhinosinusitis 8 | 512
Leigh disease 7 | 81
Mammary Neoplasms 7 | 410
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
gastric cancer 7 | 436
nasopharyngeal carcinoma 7 | 1,056
Amyotrophic Lateral Sclerosis 6 | 432
Hypertrophic Cardiomyopathy 6 | 56
Multiple Sclerosis 6 | 498
Neuropathy 6 | 210
Stomach Neoplasms 6 | 282
primary Sjogren syndrome 6 | 788
tuberculosis and treatment for 3 months 6 | 327
Barrett's esophagus 5 | 185
Cardiomyopathy 5 | 110
Deafness dystonia syndrome 5 | 20
Dystonia 5 | 77
Endometriosis 5 | 535
IGA Glomerulonephritis 5 | 454
Intellectual disability 5 | 573
Myocardial Ischemia 5 | 169
Renal Cell Carcinoma 5 | 199
Vascular disease 5 | 281
aldosterone-producing adenoma 5 | 664
cutaneous lupus erythematosus 5 | 1,056
gastric carcinoma 5 | 832
hypoparathyroidism-retardation-dysmorphism syndrome 5 | 7
inflammatory breast cancer 5 | 404
Becker muscular dystrophy 4 | 187
Crohn's disease 4 | 304

Tissue

Blood and immune system 190 | 17,994
Cardiovascular System 190 | 17,957
Digestive Tract 190 | 18,472
Female tissues 190 | 18,646
Liver and Pancreas 190 | 18,135
Male tissues 190 | 17,968
Nervous System 190 | 18,560
Urinary Tract 190 | 18,443
Endocrine System 189 | 18,511
Respiratory system 187 | 17,483
Skin and soft tissues 187 | 18,114

Target Family

Non-IDG 162 | 11,969
Enzyme 33 | 4,146
Transcription Factor 2 | 1,400
Transporter 1 | 473

UniProt Keyword

Chaperone 198 | 198
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine-threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-complex protein 1 subunit alpha TCP1 Tbio Non-IDG -2.24310 169.4 383
Alpha-crystallin A chain CRYAA Tbio Non-IDG -2.83468 658.4 164
DnaJ homolog subfamily C member 9 DNAJC9 Tbio Non-IDG -0.73182 5.58 82
Calreticulin CALR Tbio Non-IDG -3.16449 1423.9 650
Sacsin SACS Tbio Non-IDG -2.60343 385.2 9
Alpha-hemoglobin-stabilizing protein AHSP Tbio Non-IDG -1.99625 96.5 108
Serpin H1 SERPINH1 Tbio Non-IDG -3.15406 1424.1 295
Peptidyl-prolyl cis-trans isomerase H PPIH Tbio Enzyme -1.31939 21.7 63
T-complex protein 1 subunit theta-like 2 CCT8L2 Tdark Non-IDG 0.70 0.09 135
Heat shock 70 kDa protein 14 HSPA14 Tbio Non-IDG -1.54331 38.4 79