Development Level

Tbio 22 | 11,651
Tdark 2 | 6,593
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal skin coloration 1 | 25
abnormal skin morphology 1 | 50
abnormal testis morphology 1 | 43
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged pancreas 1 | 2
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased circulating calcium ... 1 | 34
increased heart rate variabili... 1 | 7
increased lean body mass 1 | 172
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small testis 1 | 58

Disease

osteosarcoma 18 | 7,950
ovarian cancer 17 | 8,520
Carcinoma 16 | 11,493
glioblastoma 14 | 5,792
psoriasis 14 | 6,694
Breast cancer 13 | 3,578
invasive ductal carcinoma 13 | 2,951
ductal carcinoma in situ 12 | 1,745
pancreatic cancer 12 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
medulloblastoma, large-cell 11 | 6,241
Astrocytoma, Pilocytic 10 | 3,081
adult high grade glioma 9 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Kidney cancer 8 | 2,613
breast carcinoma 8 | 1,638
ependymoma 8 | 4,679
lung cancer 8 | 4,740
lung carcinoma 8 | 2,843
atypical teratoid / rhabdoid tumor 7 | 5,112
cystic fibrosis 7 | 1,696
group 3 medulloblastoma 7 | 4,104
interstitial cystitis 7 | 2,312
juvenile dermatomyositis 7 | 1,187
malignant mesothelioma 7 | 3,232
Duchenne muscular dystrophy 6 | 601
adrenocortical carcinoma 6 | 1,428
diabetes mellitus 6 | 1,728
group 4 medulloblastoma 6 | 1,855
oligodendroglioma 6 | 2,850
primary pancreatic ductal adenocarcinoma 6 | 1,109
ulcerative colitis 6 | 1,819
Schizophrenia 5 | 1,160
acute quadriplegic myopathy 5 | 1,158
astrocytic glioma 5 | 2,597
fibroadenoma 5 | 559
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
Kidney disease 4 | 430
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
tuberculosis 4 | 2,010
Autosomal recessive predisposition 3 | 1,442
Cancer 3 | 2,499
Endometrial cancer 3 | 311
Focal glomerulosclerosis 3 | 37
Glomerulosclerosis, Focal Segmental 3 | 28
Hydrolethalus syndrome 3 | 128
Liver cancer 3 | 604
Nonsyndromic deafness 3 | 142
Polycystic ovary syndrome 3 | 360
Rheumatoid arthritis 3 | 1,191
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
gastric carcinoma 3 | 807
primitive neuroectodermal tumor 3 | 3,035
sonic hedgehog group medulloblastoma 3 | 467
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
urothelial carcinoma 3 | 318
Amyotrophic lateral sclerosis 2 | 451
Anemia 2 | 365
Anemia, Hemolytic 2 | 55
Anemia, hereditary spherocytic hemolytic 2 | 5
Animal Mammary Neoplasms 2 | 136
Atopic dermatitis 2 | 952
Becker muscular dystrophy 2 | 191
Breast Neoplasms 2 | 445
Chronic kidney disease stage 5 2 | 31
Colonic Neoplasms 2 | 142
Congenital hemolytic anemia 2 | 32
Down syndrome 2 | 499
Hereditary elliptocytosis 2 | 22
Hereditary spherocytosis 2 | 16
Hypertension 2 | 396
Hypertensive disease 2 | 292
Increase in blood pressure 2 | 119
Intellectual disability 2 | 1,016
Kindler syndrome 2 | 11
Liver Cirrhosis, Experimental 2 | 769
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Mesothelioma, Malignant 2 | 105
Microscopic hematuria 2 | 9
Neoplasm Invasiveness 2 | 161
Osteomalacia 2 | 35
Prostatic Neoplasms 2 | 495
Proteinuria 2 | 144
Sensorineural hearing loss 2 | 106
Spherocytosis 2 | 5
acute myeloid leukemia 2 | 783
aldosterone-producing adenoma 2 | 665
hepatocellular carcinoma 2 | 547
inflammatory breast cancer 2 | 286
interstitial lung disease 2 | 298
pancreatic carcinoma 2 | 562

Tissue

Blood and immune system 25 | 16,909
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Skin and soft tissues 25 | 17,230
Liver and Pancreas 24 | 16,750
Male tissues 24 | 17,142
Digestive Tract 23 | 17,369
Nervous System 23 | 16,725
Urinary Tract 23 | 16,678
Cardiovascular System 22 | 15,192
Respiratory system 22 | 16,393

Target Family

Non-IDG 22 | 12,091
Enzyme 2 | 4,145
Transporter 1 | 473

UniProt Keyword

Cell shape 25 | 25
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytoplasmic FMR1-interacting protein 1 CYFIP1 Tbio Non-IDG -1.46134 28.5 64
Cdc42 effector protein 3 CDC42EP3 Tbio Non-IDG -1.57638 37.5 124
Ezrin EZR Tbio Non-IDG -2.99865 981.3 1088
Podoplanin PDPN Tbio Non-IDG -3.34579 2142.9 847
Erythrocyte membrane protein band 4.2 EPB42 Tbio Enzyme -0.95726 6.65 66
Alpha-parvin PARVA Tbio Non-IDG -2.38332 236.6 0
Filamin-binding LIM protein 1 FBLIM1 Tbio Non-IDG -1.33342 25.9 177
Cdc42 effector protein 4 CDC42EP4 Tdark Non-IDG -0.54214 4.05 112
Rho-related GTP-binding protein RhoJ RHOJ Tbio Enzyme -2.68242 485.1 232
Fermitin family homolog 2 FERMT2 Tbio Non-IDG -1.88943 85.7 180