Development Level

Tbio 594 | 11,445
Tdark 121 | 6,588
Tchem 73 | 1,598
Tclin 38 | 613

Collection

RFA-RM-18-021 17 | 328
Kinase: IDG Consortium (Comple... 8 | 37
Kinase: IDG Consortium (Target... 8 | 125
Ion Channel: IDG Consortium (T... 7 | 99
GPCR: IDG Consortium (Targets) 5 | 126
GPCR: IDG Consortium (Complete... 3 | 25

IMPC Phenotype

preweaning lethality, complete... 51 | 979
preweaning lethality, incomple... 33 | 499
abnormal behavior 26 | 298
abnormal embryo size 16 | 220
hyperactivity 16 | 148
decreased total body fat amoun... 15 | 207
increased lean body mass 15 | 172
embryonic lethality prior to t... 13 | 278
increased bone mineral content 13 | 108
decreased body weight 11 | 161
decreased grip strength 11 | 116
decreased vertical activity 11 | 208
edema 11 | 59
increased mean corpuscular vol... 11 | 92
male infertility 11 | 123
abnormal bone structure 9 | 187
embryonic growth retardation 9 | 106
increased circulating sodium l... 9 | 71
abnormal retina morphology 8 | 71
decreased circulating choleste... 8 | 93
hypoactivity 8 | 132
increased circulating chloride... 8 | 41
increased or absent threshold ... 8 | 101
increased startle reflex 8 | 112
abnormal eye morphology 7 | 68
decreased bone mineral content 7 | 151
decreased circulating HDL chol... 7 | 68
decreased circulating glucose ... 7 | 126
decreased lean body mass 7 | 135
improved glucose tolerance 7 | 79
increased circulating alkaline... 7 | 122
increased fasted circulating g... 7 | 76
increased heart weight 7 | 62
increased mean corpuscular hem... 7 | 96
increased total body fat amoun... 7 | 134
prenatal lethality prior to he... 7 | 87
abnormal behavioral response t... 6 | 66
abnormal embryo turning 6 | 31
decreased circulating triglyce... 6 | 79
decreased prepulse inhibition 6 | 82
decreased startle reflex 6 | 75
embryonic lethality prior to o... 6 | 239
impaired glucose tolerance 6 | 75
abnormal sleep behavior 5 | 70
decreased bone mineral density 5 | 126
decreased circulating alanine ... 5 | 47
decreased circulating alkaline... 5 | 46
decreased circulating insulin ... 5 | 76
decreased circulating total pr... 5 | 49
decreased mean corpuscular vol... 5 | 79
increased bone mineral density 5 | 72
increased vertical activity 5 | 24
persistence of hyaloid vascula... 5 | 33
abnormal cornea morphology 4 | 31
abnormal neural tube closure 4 | 46
abnormal pericardium morpholog... 4 | 26
cardiovascular system phenotyp... 4 | 36
cataract 4 | 92
decreased body length 4 | 101
decreased caudal vertebrae num... 4 | 53
decreased circulating LDL chol... 4 | 38
decreased circulating aspartat... 4 | 34
decreased circulating serum al... 4 | 82
decreased leukocyte cell numbe... 4 | 73
enlarged heart 4 | 210
increased blood urea nitrogen ... 4 | 48
small testis 4 | 58
abnormal coat-hair pigmentatio... 3 | 64
abnormal craniofacial morpholo... 3 | 33
abnormal hindbrain morphology 3 | 10
abnormal locomotor behavior 3 | 24
abnormal midbrain morphology 3 | 10
abnormal placenta size 3 | 20
abnormal retinal blood vessel ... 3 | 26
abnormal retinal inner nuclear... 3 | 8
abnormal retinal vasculature m... 3 | 27
abnormal seminal vesicle morph... 3 | 114
abnormal spleen morphology 3 | 55
decreased T cell number 3 | 15
decreased circulating fructosa... 3 | 30
decreased circulating iron lev... 3 | 32
decreased circulating potassiu... 3 | 20
decreased exploration in new e... 3 | 11
decreased fasted circulating g... 3 | 65
decreased neutrophil cell numb... 3 | 42
female infertility 3 | 60
impaired pupillary reflex 3 | 26
increased body weight 3 | 25
increased circulating calcium ... 3 | 34
increased circulating choleste... 3 | 66
increased circulating free fat... 3 | 20
increased grip strength 3 | 41
increased prepulse inhibition 3 | 32
pallor 3 | 34
polycystic kidney 3 | 15
short tibia 3 | 97
small superior vagus ganglion 3 | 74
thrombocytopenia 3 | 56
tremors 3 | 39
decreased hemoglobin content 2 | 68

Disease

Carcinoma 629 | 11,493
osteosarcoma 403 | 7,950
ovarian cancer 389 | 8,520
medulloblastoma, large-cell 355 | 6,241
ependymoma 337 | 4,679
glioblastoma 332 | 5,792
psoriasis 297 | 6,694
atypical teratoid / rhabdoid tumor 292 | 5,112
adult high grade glioma 228 | 3,801
lung cancer 219 | 4,740
Kidney cancer 218 | 2,613
group 3 medulloblastoma 215 | 4,104
Breast cancer 205 | 3,578
Astrocytoma, Pilocytic 187 | 3,081
lung carcinoma 177 | 2,843
oligodendroglioma 171 | 2,850
primitive neuroectodermal tumor 162 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 161 | 2,955
invasive ductal carcinoma 161 | 2,951
astrocytic glioma 158 | 2,597
malignant mesothelioma 151 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 150 | 2,989
lung adenocarcinoma 144 | 2,716
non-small cell lung cancer 137 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 135 | 3,291
pancreatic cancer 129 | 2,398
interstitial cystitis 123 | 2,312
subependymal giant cell astrocytoma 117 | 2,287
Pick disease 114 | 1,894
pituitary cancer 108 | 1,972
Cancer 100 | 2,499
group 4 medulloblastoma 97 | 1,855
Intellectual disability 96 | 1,016
Autosomal recessive predisposition 93 | 1,442
ulcerative colitis 93 | 1,819
tuberculosis 91 | 2,010
chronic rhinosinusitis 90 | 512
ductal carcinoma in situ 90 | 1,745
nasopharyngeal carcinoma 89 | 1,058
cystic fibrosis 87 | 1,696
colon cancer 84 | 1,478
Schizophrenia 77 | 1,160
breast carcinoma 73 | 1,638
Liver cancer 72 | 604
pancreatic ductal adenocarcinoma liver metastasis 70 | 1,962
adrenocortical carcinoma 60 | 1,428
primary pancreatic ductal adenocarcinoma 60 | 1,109
spina bifida 60 | 1,074
Dull intelligence 59 | 645
Low intelligence 59 | 645
Mental Retardation 59 | 645
Mental deficiency 59 | 645
Poor school performance 59 | 645
acute quadriplegic myopathy 57 | 1,158
astrocytoma 57 | 1,146
pediatric high grade glioma 57 | 1,064
juvenile dermatomyositis 55 | 1,187
Polydactyly 52 | 107
cutaneous lupus erythematosus 52 | 1,057
diabetes mellitus 52 | 1,728
Obesity 50 | 678
Melanoma 47 | 711
gastric carcinoma 47 | 807
Alzheimer's disease 46 | 658
Retinitis Pigmentosa 46 | 226
Ciliopathy 45 | 71
progressive supranuclear palsy 45 | 676
Epilepsy 44 | 792
Nephronophthisis 44 | 80
Joubert syndrome 43 | 66
Bipolar Disorder 42 | 666
Primary ciliary dyskinesia 42 | 76
dermatomyositis 42 | 966
Cognitive delay 41 | 608
Global developmental delay 41 | 608
Mental and motor retardation 41 | 608
Muscle hypotonia 41 | 571
Rheumatoid arthritis 41 | 1,191
aldosterone-producing adenoma 41 | 665
Nystagmus 40 | 317
posterior fossa group B ependymoma 40 | 416
Atopic dermatitis 38 | 952
Skin cancer 37 | 469
Waldenstrons macroglobulinemia 37 | 765
active Crohn's disease 37 | 922
esophageal adenocarcinoma 37 | 737
Neurodegenerative disease 35 | 414
Short stature 35 | 531
non primary Sjogren syndrome sicca 35 | 891
sonic hedgehog group medulloblastoma 35 | 467
Bardet-Biedl syndrome 34 | 51
Cerebellar Ataxia 34 | 304
Liver Cirrhosis, Experimental 34 | 769
Multiple myeloma 34 | 1,332
Amyotrophic lateral sclerosis 33 | 451
Seizures 33 | 596
medulloblastoma 33 | 720
autosomal dominant Emery-Dreifuss muscular dystrophy 32 | 510
Cataract 31 | 297
Congenital hypoplasia of penis 31 | 176

Tissue

Endocrine System 813 | 18,159
Female tissues 793 | 17,400
Male tissues 789 | 17,142
Digestive Tract 788 | 17,369
Skin and soft tissues 788 | 17,230
Nervous System 782 | 16,725
Liver and Pancreas 769 | 16,750
Respiratory system 765 | 16,393
Urinary Tract 765 | 16,678
Blood and immune system 764 | 16,909
Cardiovascular System 693 | 15,192

Target Family

Non-IDG 583 | 12,091
Enzyme 111 | 4,145
Kinase 52 | 634
Ion Channel 37 | 344
GPCR 19 | 408
Transporter 12 | 473
Epigenetic 6 | 242
Transcription Factor 5 | 1,400
Nuclear Receptor 1 | 48

UniProt Keyword

Cell projection 826 | 826
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutaredoxin domain-containing cysteine-rich protein 2 GRXCR2 Tbio Non-IDG 0.00000 1.00 14
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
Septin-11 SEPT11 Tbio Non-IDG -1.47747 32.4 127
Rab-3A-interacting protein RAB3IP Tbio Non-IDG -1.03500 11.6 89
CAP-Gly domain-containing linker protein 1 CLIP1 Tbio Non-IDG -2.54943 343.7 221
Neuromodulin GAP43 Tbio Non-IDG -2.93905 762.9 597
Unconventional prefoldin RPB5 interactor 1 URI1 Tbio Enzyme -2.15409 134.8 150
Transient receptor potential cation channel subfamily M member 2 TRPM2 Tchem Ion Channel -1.34318 25.1 209
T-complex protein 11 homolog TCP11 Tbio Non-IDG -1.26152 18.0 80
FH1/FH2 domain-containing protein 1 FHOD1 Tbio Non-IDG -1.49217 38.9 120