Development Level

Tbio 274 | 10,625
Tchem 56 | 1,890
Tdark 39 | 7,003
Tclin 3 | 602

Collection

Eligible Kinase Proteins 5 | 134

IMPC Term

preweaning lethality, complete... 36 | 633
preweaning lethality, incomple... 11 | 260
embryonic lethality prior to o... 10 | 148
embryonic lethality prior to t... 10 | 187
abnormal embryo size 6 | 112
decreased body weight 6 | 174
abnormal coat/hair pigmentatio... 5 | 54
decreased lean body mass 5 | 195
embryonic growth retardation 5 | 28
increased fasted circulating g... 5 | 68
abnormal behavior 4 | 226
improved glucose tolerance 4 | 56
increased leukocyte cell numbe... 4 | 37
increased or absent threshold ... 4 | 128
thrombocytopenia 4 | 46
abnormal gait 3 | 51
abnormal retina morphology 3 | 100
decreased bone mineral content 3 | 157
decreased circulating serum al... 3 | 79
decreased grip strength 3 | 123
decreased total body fat amoun... 3 | 186
hypoactivity 3 | 89
increased bone mineral density 3 | 52
increased circulating HDL chol... 3 | 63
increased circulating sodium l... 3 | 71
increased mean corpuscular hem... 3 | 93
increased mean corpuscular vol... 3 | 91
male infertility 3 | 62
tremors 3 | 34
abnormal bone structure 2 | 131
abnormal craniofacial morpholo... 2 | 12
abnormal cranium morphology 2 | 32
abnormal kidney morphology 2 | 30
abnormal optic disc morphology 2 | 10
abnormal placenta morphology 2 | 4
abnormal placenta size 2 | 10
abnormal seminal vesicle morph... 2 | 47
abnormal snout morphology 2 | 18
anophthalmia 2 | 20
decreased circulating aspartat... 2 | 27
decreased circulating choleste... 2 | 85
decreased circulating glucose ... 2 | 121
decreased erythrocyte cell num... 2 | 43
decreased lumbar vertebrae num... 2 | 62
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular vol... 2 | 50
decreased rib number 2 | 59
hyperactivity 2 | 108
increased circulating alkaline... 2 | 119
increased circulating chloride... 2 | 43
increased circulating choleste... 2 | 53
increased exploration in new e... 2 | 56
increased grip strength 2 | 83
increased lean body mass 2 | 107
increased rib number 2 | 41
microphthalmia 2 | 15
prenatal lethality 2 | 16
short tibia 2 | 82
small spleen 2 | 11
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal body wall morphology 1 | 7
abnormal coat appearance 1 | 25
abnormal eye morphology 1 | 38
abnormal neural tube closure 1 | 37
abnormal skin morphology 1 | 23
abnormal testis morphology 1 | 30
abnormal thoracic vertebrae mo... 1 | 16
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
decreased IgG1 level 1 | 4
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased cervical vertebrae n... 1 | 12
decreased circulating chloride... 1 | 32
decreased circulating creatini... 1 | 31
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased gamma-delta T cell n... 1 | 18
decreased hematocrit 1 | 25
decreased thoracic vertebrae n... 1 | 7
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
female infertility 1 | 34
hydrops fetalis 1 | 22
increased CD4-positive, CD25-p... 1 | 18
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased circulating alanine ... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating triglyce... 1 | 24
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
prenatal lethality prior to he... 1 | 64
shortened PQ interval 1 | 6
straub tail 1 | 26
vertebral fusion 1 | 23

Disease

ovarian cancer 241 | 8,484
medulloblastoma, large-cell 193 | 6,234
osteosarcoma 186 | 7,933
glioblastoma 178 | 5,572
psoriasis 164 | 6,685
primitive neuroectodermal tumor 143 | 3,031
lung cancer 139 | 4,466
Breast cancer 125 | 3,094
atypical teratoid / rhabdoid tumor 125 | 4,369
non-small cell lung cancer 113 | 2,798
pediatric high grade glioma 111 | 2,712
intraductal papillary-mucinous carcinoma (IPMC) 110 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 107 | 3,289
malignant mesothelioma 107 | 3,162
invasive ductal carcinoma 101 | 2,950
group 3 medulloblastoma 95 | 2,254
Cancer 92 | 2,346
adrenocortical carcinoma 92 | 1,427
lung adenocarcinoma 90 | 2,713
ductal carcinoma in situ 72 | 1,745
pancreatic cancer 71 | 2,300
oligodendroglioma 70 | 2,849
breast carcinoma 66 | 1,614
colon cancer 62 | 1,475
pilocytic astrocytoma 62 | 3,086
posterior fossa group A ependymoma 61 | 1,511
Atopic dermatitis 60 | 944
nasopharyngeal carcinoma 59 | 1,056
Endometriosis 56 | 535
ependymoma 54 | 2,514
Multiple myeloma 51 | 1,327
sonic hedgehog group medulloblastoma 51 | 1,482
Carcinoma 50 | 2,147
Pick disease 50 | 1,893
atypical teratoid/rhabdoid tumor 47 | 1,095
intraductal papillary-mucinous adenoma (IPMA) 43 | 2,956
astrocytic glioma 42 | 2,241
astrocytoma 42 | 1,493
subependymal giant cell astrocytoma 42 | 2,287
ulcerative colitis 42 | 2,087
adult high grade glioma 41 | 2,148
medulloblastoma 38 | 1,524
Waldenstrons macroglobulinemia 36 | 765
interstitial cystitis 36 | 2,299
IGA Glomerulonephritis 35 | 454
group 4 medulloblastoma 34 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 33 | 1,795
pituitary cancer 32 | 1,972
tuberculosis 32 | 1,557
Rheumatoid Arthritis 31 | 1,160
posterior fossa group B ependymoma 30 | 1,530
dermatomyositis 28 | 933
acute quadriplegic myopathy 27 | 1,157
lung carcinoma 27 | 2,844
primary Sjogren syndrome 24 | 789
primary pancreatic ductal adenocarcinoma 24 | 1,271
progressive supranuclear palsy 23 | 674
juvenile dermatomyositis 22 | 1,189
diabetes mellitus 21 | 1,663
non primary Sjogren syndrome sicca 21 | 840
inflammatory breast cancer 20 | 404
Microcephaly 18 | 149
active Crohn's disease 18 | 918
Intellectual disability 17 | 573
acute myeloid leukemia 17 | 780
esophageal adenocarcinoma 16 | 737
spina bifida 16 | 1,064
Polycystic Ovary Syndrome 15 | 332
cystic fibrosis 13 | 1,665
pancreatic carcinoma 13 | 567
tuberculosis and treatment for 6 months 13 | 686
Type 2 diabetes mellitus 12 | 189
gastric carcinoma 12 | 832
Alzheimer's disease 11 | 644
Amyotrophic Lateral Sclerosis 11 | 431
Peripheral Neuropathy 11 | 303
chronic rhinosinusitis 11 | 512
cutaneous lupus erythematosus 11 | 1,056
Acquired metabolic disease 10 | 267
cystic fibrosis and chronic rhinosinusitis 10 | 213
Bipolar Disorder 9 | 266
Down syndrome 9 | 548
Mammary Neoplasms 9 | 410
Crohn's disease 8 | 304
Neurodegenerative disease 8 | 383
Stomach Neoplasms 8 | 282
gastric cancer 8 | 430
hereditary spastic paraplegia 8 | 313
tuberculosis and treatment for 3 months 8 | 327
Colorectal Neoplasms 7 | 217
Duchenne muscular dystrophy 7 | 602
Lissencephaly 7 | 61
Male infertility 7 | 170
Mammary Neoplasms, Experimental 7 | 150
Roberts syndrome 7 | 16
aldosterone-producing adenoma 7 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
interstitial lung disease 7 | 291
mucosa-associated lymphoid tissue lymphoma 7 | 480
non-small cell lung carcinoma 7 | 413

Tissue

Blood and immune system 370 | 17,995
Cardiovascular System 370 | 17,958
Digestive Tract 370 | 18,473
Endocrine System 370 | 18,512
Female tissues 370 | 18,647
Liver and Pancreas 370 | 18,136
Male tissues 370 | 17,969
Nervous System 370 | 18,561
Skin and soft tissues 370 | 18,115
Urinary Tract 370 | 18,444
Respiratory system 369 | 17,484

Target Family

Non-IDG 265 | 11,971
Enzyme 61 | 4,146
Kinase 37 | 634
Transcription Factor 4 | 1,400
Epigenetic 3 | 242
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

UniProt Keyword

Cell division 372 | 372
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Microtubule-associated protein RP/EB family member 3 MAPRE3 Tbio Non-IDG -2.14681 132.5 161
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.21092 1667.7 216
Kinetochore protein Nuf2 NUF2 Tbio Non-IDG -1.66072 48.8 98
Centrosomal protein of 164 kDa CEP164 Tbio Non-IDG -0.96655 10.2 84
Dynein light chain Tctex-type 1 DYNLT1 Tbio Non-IDG -2.32941 210.3 40
Centromere protein F CENPF Tbio Non-IDG -1.98596 103.0 180
Histone H3-like centromeric protein A CENPA Tbio Non-IDG -2.68837 532.8 347
Golgin subfamily A member 2 GOLGA2 Tbio Non-IDG -1.94177 80.5 168