Development Level

Tbio 316 | 10,625
Tdark 84 | 7,003
Tchem 63 | 1,890
Tclin 19 | 602

Collection

Eligible Ion Channel Proteins 2 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 13 | 633
abnormal behavior 8 | 226
decreased bone mineral density 7 | 126
decreased grip strength 7 | 123
decreased total body fat amoun... 7 | 186
tremors 6 | 34
abnormal bone structure 5 | 131
abnormal sleep behavior 5 | 63
decreased bone mineral content 5 | 157
enlarged heart 5 | 111
impaired glucose tolerance 5 | 52
increased bone mineral content 5 | 92
short tibia 5 | 82
decreased circulating choleste... 4 | 85
decreased circulating glucose ... 4 | 121
decreased circulating insulin ... 4 | 75
decreased lean body mass 4 | 195
edema 4 | 11
improved glucose tolerance 4 | 56
increased circulating alkaline... 4 | 119
increased lean body mass 4 | 107
increased vertical activity 4 | 18
preweaning lethality, incomple... 4 | 260
abnormal gait 3 | 51
abnormal lens morphology 3 | 73
abnormal locomotor activation 3 | 26
decreased fasted circulating g... 3 | 49
decreased pulmonary respirator... 3 | 4
increased bone mineral density 3 | 52
increased circulating potassiu... 3 | 31
increased circulating sodium l... 3 | 71
increased exploration in new e... 3 | 56
increased hemoglobin content 3 | 45
increased or absent threshold ... 3 | 128
persistence of hyaloid vascula... 3 | 22
thrombocytopenia 3 | 46
abnormal bone mineralization 2 | 55
abnormal heart left ventricle ... 2 | 20
abnormal limb morphology 2 | 7
abnormal response to new envir... 2 | 8
abnormal retina morphology 2 | 100
abnormal tail morphology 2 | 17
abnormal tooth morphology 2 | 24
corneal opacity 2 | 25
decreased basophil cell number 2 | 11
decreased body length 2 | 108
decreased circulating HDL chol... 2 | 77
decreased circulating alkaline... 2 | 41
decreased circulating creatini... 2 | 31
decreased circulating total pr... 2 | 41
decreased circulating triglyce... 2 | 83
decreased heart weight 2 | 44
decreased hemoglobin content 2 | 53
decreased leukocyte cell numbe... 2 | 54
decreased mature B cell number 2 | 25
enlarged stomach 2 | 2
hemorrhage 2 | 12
hydrops fetalis 2 | 22
hyperactivity 2 | 108
impaired righting response 2 | 19
increased circulating chloride... 2 | 43
increased circulating iron lev... 2 | 25
increased circulating triglyce... 2 | 24
increased fasted circulating g... 2 | 68
increased heart weight 2 | 37
increased hematocrit 2 | 36
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
increased startle reflex 2 | 38
lethargy 2 | 5
small thymus 2 | 11
straub tail 2 | 26
abnormal behavioral response t... 1 | 52
abnormal cornea morphology 1 | 24
abnormal ear morphology 1 | 5
abnormal embryo size 1 | 112
abnormal heart morphology 1 | 51
abnormal spleen morphology 1 | 36
abnormal tail movements 1 | 12
abnormal whole-body plethysmog... 1 | 4
convulsive seizures 1 | 11
decreased Ly6C high monocyte n... 1 | 18
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased cervical vertebrae n... 1 | 12
decreased circulating bilirubi... 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating potassiu... 1 | 17
decreased eosinophil cell numb... 1 | 41
decreased mean corpuscular hem... 1 | 34
decreased neutrophil cell numb... 1 | 37
decreased vertical activity 1 | 22
enlarged spleen 1 | 26
increased NK cell number 1 | 19
increased body length 1 | 20
increased grip strength 1 | 83
increased mean platelet volume 1 | 19
long tibia 1 | 13
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64

Disease

psoriasis 225 | 6,685
ovarian cancer 222 | 8,484
glioblastoma 212 | 5,572
osteosarcoma 210 | 7,933
Carcinoma 200 | 2,147
medulloblastoma, large-cell 192 | 6,234
lung carcinoma 168 | 2,844
atypical teratoid / rhabdoid tumor 159 | 4,369
lung cancer 148 | 4,466
pilocytic astrocytoma 141 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 137 | 2,956
invasive ductal carcinoma 137 | 2,950
Breast cancer 134 | 3,094
interstitial cystitis 134 | 2,299
malignant mesothelioma 128 | 3,162
non-small cell lung cancer 128 | 2,798
lung adenocarcinoma 126 | 2,713
intraductal papillary-mucinous carcinoma (IPMC) 124 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 124 | 3,289
pediatric high grade glioma 124 | 2,712
Cancer 115 | 2,346
pancreatic cancer 111 | 2,300
oligodendroglioma 106 | 2,849
primitive neuroectodermal tumor 98 | 3,031
ulcerative colitis 95 | 2,087
ependymoma 90 | 2,514
pituitary cancer 90 | 1,972
subependymal giant cell astrocytoma 90 | 2,287
cystic fibrosis 86 | 1,665
group 4 medulloblastoma 86 | 1,875
primary pancreatic ductal adenocarcinoma 82 | 1,271
ductal carcinoma in situ 80 | 1,745
adult high grade glioma 79 | 2,148
breast carcinoma 76 | 1,614
posterior fossa group A ependymoma 73 | 1,511
astrocytic glioma 69 | 2,241
colon cancer 66 | 1,475
cutaneous lupus erythematosus 62 | 1,056
gastric carcinoma 62 | 832
astrocytoma 61 | 1,493
sonic hedgehog group medulloblastoma 61 | 1,482
tuberculosis 60 | 1,557
adrenocortical carcinoma 57 | 1,427
Pick disease 52 | 1,893
medulloblastoma 52 | 1,524
Duchenne muscular dystrophy 50 | 602
group 3 medulloblastoma 50 | 2,254
nasopharyngeal carcinoma 48 | 1,056
diabetes mellitus 47 | 1,663
esophageal adenocarcinoma 46 | 737
posterior fossa group B ependymoma 46 | 1,530
juvenile dermatomyositis 45 | 1,189
autosomal dominant Emery-Dreifuss muscular dystrophy 43 | 499
Atopic dermatitis 39 | 944
atypical teratoid/rhabdoid tumor 37 | 1,095
Rheumatoid Arthritis 35 | 1,160
dermatomyositis 35 | 933
pancreatic ductal adenocarcinoma liver metastasis 34 | 1,795
Multiple Sclerosis 33 | 498
Down syndrome 30 | 548
acute quadriplegic myopathy 30 | 1,157
Autistic Disorder 29 | 320
Kidney disease 28 | 396
fibroadenoma 28 | 557
primary Sjogren syndrome 28 | 789
spina bifida 27 | 1,064
Alzheimer's disease 26 | 644
Intellectual disability 26 | 573
aldosterone-producing adenoma 25 | 664
urothelial carcinoma 25 | 318
Atherosclerosis 24 | 275
interstitial lung disease 24 | 291
Becker muscular dystrophy 23 | 187
Obesity 23 | 616
Endometriosis 22 | 535
Schizophrenia 22 | 501
active Crohn's disease 22 | 918
mucosa-associated lymphoid tissue lymphoma 22 | 480
non-small cell lung carcinoma 22 | 413
progressive supranuclear palsy 22 | 674
non primary Sjogren syndrome sicca 21 | 840
Coronary artery disease 20 | 240
IGA Glomerulonephritis 20 | 454
head and neck cancer 20 | 270
Vascular disease 19 | 281
Asthma 18 | 349
Prostatic Neoplasms 18 | 471
Heart disease 17 | 279
Hypersensitivity reaction type II disease 17 | 235
Mammary Neoplasms 17 | 410
Spontaneous abortion 17 | 108
active ulcerative colitis 17 | 477
acute myeloid leukemia 17 | 780
Arthritis 16 | 248
Colorectal Neoplasms 16 | 217
Kidney cancer 16 | 118
glioblastoma multiforme 16 | 347
non diabetic and post-ischemic heart failure 16 | 200
nephrosclerosis 15 | 329
periodontitis 15 | 269

Tissue

Digestive Tract 477 | 18,473
Female tissues 477 | 18,647
Liver and Pancreas 475 | 18,136
Nervous System 475 | 18,561
Urinary Tract 475 | 18,444
Endocrine System 473 | 18,512
Male tissues 473 | 17,969
Cardiovascular System 472 | 17,958
Blood and immune system 470 | 17,995
Respiratory system 469 | 17,484
Skin and soft tissues 469 | 18,115

Target Family

Non-IDG 421 | 11,971
Enzyme 29 | 4,146
Kinase 20 | 634
GPCR 5 | 406
Ion Channel 3 | 341
Transporter 3 | 473
Transcription Factor 1 | 1,400

UniProt Keyword

Cell adhesion 482 | 482
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
EGF-like repeat and discoidin I-like domain-containing protein 3 EDIL3 Tbio Non-IDG -1.83671 93.1 157
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 AIMP1 Tbio Enzyme -2.04569 136.6 321
Laminin subunit alpha-2 LAMA2 Tbio Non-IDG -2.48634 321.9 131
Sialoadhesin SIGLEC1 Tbio Non-IDG -2.22508 195.6 309
Contactin-6 CNTN6 Tbio Non-IDG -2.02527 101.3 65
Inactive ribonuclease-like protein 10 RNASE10 Tdark Enzyme -0.65321 4.33 16
Galectin-3-binding protein LGALS3BP Tbio Non-IDG -2.79457 669.7 172
Collagen alpha-3(VI) chain COL6A3 Tbio Non-IDG -1.73777 56.3 29
Contactin-associated protein-like 5 CNTNAP5 Tdark Non-IDG -0.52403 3.89 4
Potassium-transporting ATPase subunit beta ATP4B Tclin Transporter -0.76953 6.01 159