Development Level

Tbio 18 | 11,445
Tchem 11 | 1,598
Tdark 3 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
decreased grip strength 2 | 116
abnormal embryo size 1 | 220
abnormal kidney morphology 1 | 65
abnormal locomotor behavior 1 | 24
abnormal seminal vesicle morph... 1 | 114
aorta stenosis 1 | 2
cataract 1 | 92
decreased circulating chloride... 1 | 30
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased food intake 1 | 13
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged liver 1 | 2
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased anxiety-related resp... 1 | 2
increased fasted circulating g... 1 | 76
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
preweaning lethality, complete... 1 | 979
prolonged ST segment 1 | 36

Disease

Carcinoma 28 | 11,493
ovarian cancer 18 | 8,520
psoriasis 13 | 6,694
glioblastoma 12 | 5,792
medulloblastoma, large-cell 12 | 6,241
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
diabetes mellitus 10 | 1,728
lung cancer 10 | 4,740
osteosarcoma 10 | 7,950
atypical teratoid / rhabdoid tumor 9 | 5,112
ependymoma 9 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung adenocarcinoma 9 | 2,716
non-small cell lung cancer 9 | 2,890
oligodendroglioma 8 | 2,850
Astrocytoma, Pilocytic 7 | 3,081
adult high grade glioma 7 | 3,801
interstitial cystitis 7 | 2,312
invasive ductal carcinoma 7 | 2,951
lung carcinoma 7 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Breast cancer 6 | 3,578
Kidney cancer 6 | 2,613
astrocytic glioma 6 | 2,597
group 3 medulloblastoma 6 | 4,104
active Crohn's disease 5 | 922
astrocytoma 5 | 1,146
cystic fibrosis 5 | 1,696
malignant mesothelioma 5 | 3,232
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Asthma 4 | 385
Atopic dermatitis 4 | 952
Cancer 4 | 2,499
Diabetic Nephropathies 4 | 37
Diabetic Nephropathy 4 | 34
juvenile dermatomyositis 4 | 1,187
primitive neuroectodermal tumor 4 | 3,035
Angioedema 3 | 38
Atherosclerosis 3 | 291
Autosomal recessive predisposition 3 | 1,442
Cerebrovascular disease 3 | 238
Coronary artery disease 3 | 268
Duchenne muscular dystrophy 3 | 601
Kidney disease 3 | 430
Obesity 3 | 678
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
active ulcerative colitis 3 | 764
acute myeloid leukemia 3 | 783
colon cancer 3 | 1,478
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
progressive supranuclear palsy 3 | 676
urothelial carcinoma 3 | 318
Alcoholic Intoxication, Chronic 2 | 289
C1 inhibitor deficiency 2 | 8
Cerebral palsy 2 | 40
Cough 2 | 23
Depressive disorder 2 | 409
Down syndrome 2 | 499
Endometriosis 2 | 540
Epilepsy 2 | 792
Heart disease 2 | 306
Hyperglycemia 2 | 137
Hypertension 2 | 396
Hypertensive disease 2 | 292
Intellectual disability 2 | 1,016
Liver Cirrhosis 2 | 181
Liver Cirrhosis, Experimental 2 | 769
Lung Neoplasms 2 | 232
Lung disease 2 | 142
Mental Depression 2 | 333
Migraine 2 | 83
Multiple myeloma 2 | 1,332
Pancreatitis 2 | 123
Pick disease 2 | 1,894
Prostatic Neoplasms 2 | 495
Pulmonary hypertension 2 | 85
Severe acute respiratory syndrome 2 | 27
Silver-Russell syndrome 2 | 39
Waldenstrons macroglobulinemia 2 | 765
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,057
ductal carcinoma in situ 2 | 1,745
facioscapulohumeral dystrophy 2 | 288
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
head and neck cancer 2 | 271
mucosa-associated lymphoid tissue lymphoma 2 | 484
non primary Sjogren syndrome sicca 2 | 891
pediatric high grade glioma 2 | 1,064
primary pancreatic ductal adenocarcinoma 2 | 1,109
Alport syndrome 1 | 21
Hypertension, Pulmonary 1 | 37
Psychoses, Substance-Induced 1 | 17

Tissue

Digestive Tract 32 | 17,369
Endocrine System 32 | 18,159
Female tissues 32 | 17,400
Male tissues 32 | 17,142
Urinary Tract 32 | 16,678
Blood and immune system 31 | 16,909
Liver and Pancreas 31 | 16,750
Nervous System 31 | 16,725
Skin and soft tissues 31 | 17,230
Respiratory system 30 | 16,393
Cardiovascular System 27 | 15,192

Target Family

Enzyme 33 | 4,145

UniProt Keyword

Carboxypeptidase 33 | 33
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Carboxypeptidase Q CPQ Tbio Enzyme -2.51783 330.9 81
N-acetylated-alpha-linked acidic dipeptidase 2 NAALAD2 Tchem Enzyme -1.51589 30.6 39
Carboxypeptidase A4 CPA4 Tbio Enzyme -1.69484 48.3 61
Mast cell carboxypeptidase A CPA3 Tchem Enzyme -1.72972 50.2 151
Carboxypeptidase B CPB1 Tchem Enzyme -2.97696 883.0 228
Carboxypeptidase A1 CPA1 Tchem Enzyme -1.95541 84.1 265
Lysosomal Pro-X carboxypeptidase PRCP Tchem Enzyme -1.87633 85.9 165
Carboxypeptidase O CPO Tdark Enzyme -0.37892 2.01 101
Angiotensin-converting enzyme 2 ACE2 Tchem Enzyme -3.00188 1129.3 720
Cytosolic carboxypeptidase-like protein 5 AGBL5 Tbio Enzyme -0.97543 10.5 132