Development Level

Tchem 30 | 1,598
Tbio 19 | 11,445
Tclin 13 | 613
Tdark 6 | 6,588

Collection

Ion Channel: IDG Consortium (T... 17 | 99

IMPC Phenotype

preweaning lethality, complete... 6 | 979
increased startle reflex 4 | 112
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
embryonic lethality prior to t... 3 | 278
abnormal gait 2 | 69
decreased body weight 2 | 161
decreased circulating glucose ... 2 | 126
decreased fasted circulating g... 2 | 65
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 42
increased lean body mass 2 | 172
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
abnormal facial morphology 1 | 17
abnormal forelimb morphology 1 | 2
abnormal locomotor activation 1 | 16
abnormal pancreas morphology 1 | 13
abnormal placenta vasculature 1 | 2
abnormal response to new envir... 1 | 10
abnormal spleen morphology 1 | 55
abnormal vocalization 1 | 21
corneal vascularization 1 | 6
cyanosis 1 | 7
decreased cardiac stroke volum... 1 | 6
decreased circulating amylase ... 1 | 28
decreased circulating free fat... 1 | 31
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
edema 1 | 59
embryonic growth retardation 1 | 106
hemorrhage 1 | 23
increased circulating alanine ... 1 | 13
increased circulating chloride... 1 | 41
increased fasted circulating g... 1 | 76
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
limb grasping 1 | 41
male infertility 1 | 123
mammalian phenotype 1 | 17
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
respiratory system phenotype 1 | 2
small epididymis 1 | 3
small heart 1 | 10
small liver 1 | 8

Disease

Carcinoma 61 | 11,493
Kidney cancer 32 | 2,613
glioblastoma 31 | 5,792
atypical teratoid / rhabdoid tumor 29 | 5,112
osteosarcoma 28 | 7,950
adult high grade glioma 27 | 3,801
medulloblastoma, large-cell 27 | 6,241
ovarian cancer 26 | 8,520
psoriasis 25 | 6,694
ependymoma 22 | 4,679
Astrocytoma, Pilocytic 20 | 3,081
group 3 medulloblastoma 19 | 4,104
primitive neuroectodermal tumor 18 | 3,035
Breast cancer 16 | 3,578
oligodendroglioma 16 | 2,850
lung cancer 15 | 4,740
lung carcinoma 15 | 2,843
Pick disease 14 | 1,894
subependymal giant cell astrocytoma 13 | 2,287
Bipolar Disorder 12 | 666
Liver cancer 12 | 604
Endometrial cancer 11 | 311
astrocytic glioma 11 | 2,597
invasive ductal carcinoma 11 | 2,951
lung adenocarcinoma 11 | 2,716
Hypertension 10 | 396
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
malignant mesothelioma 10 | 3,232
pituitary cancer 10 | 1,972
Melanoma 9 | 711
Epilepsy 8 | 792
Schizophrenia 8 | 1,160
Skin cancer 8 | 469
Intellectual disability 7 | 1,016
Malignant hyperthermia 7 | 26
cutaneous lupus erythematosus 7 | 1,057
pancreatic cancer 7 | 2,398
Cancer 6 | 2,499
Endometriosis 6 | 540
Hypertensive disease 6 | 292
Hypertensive disorder 6 | 56
Neurodegenerative disease 6 | 414
colon cancer 6 | 1,478
cystic fibrosis 6 | 1,696
Amenorrhea Secondary to Ovarian Dysfunction 5 | 8
Angina Pectoris 5 | 32
Atrophic vaginitis 5 | 14
Contraception 5 | 15
Corpus Luteum Insufficiency Syndrome 5 | 8
Dentin sensitivity 5 | 14
Dysfunctional uterine bleeding 5 | 9
Endometrial Hyperplasia Prevention 5 | 9
Endometrial carcinoma 5 | 15
Infertility Secondary to Progesterone Deficiency 5 | 8
Menopausal flushing 5 | 17
Postmenopausal osteoporosis 5 | 19
Prevention of Premature Labor 5 | 9
Secondary malignant neoplasm of kidney 5 | 9
Secondary physiologic amenorrhea 5 | 32
astrocytoma 5 | 1,146
group 4 medulloblastoma 5 | 1,855
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Autosomal dominant cerebellar ataxia 4 | 33
Autosomal recessive predisposition 4 | 1,442
Cerebellar Ataxia 4 | 304
Hyperalgesia 4 | 83
Neuropathy 4 | 261
Obesity 4 | 678
Prinzmetal angina 4 | 6
Type 2 diabetes mellitus 4 | 272
breast carcinoma 4 | 1,638
diabetes mellitus 4 | 1,728
non-small cell lung cancer 4 | 2,890
pediatric high grade glioma 4 | 1,064
progressive supranuclear palsy 4 | 676
Alzheimer's disease 3 | 658
Atrial Fibrillation 3 | 124
Autistic Disorder 3 | 364
Brugada Syndrome (disorder) 3 | 15
Brugada syndrome 3 | 29
DOID:2627 3 | 94
Fever 3 | 138
Kidney disease 3 | 430
Large intestine cancer 3 | 126
Migraine 3 | 83
Myopathy 3 | 185
Postherpetic neuralgia 3 | 11
Progressive disorder 3 | 142
Psychotic Disorders 3 | 151
Rheumatoid arthritis 3 | 1,191
Thyrotoxicosis 3 | 38
Vascular disease 3 | 319
ductal carcinoma in situ 3 | 1,745
head and neck cancer 3 | 271
medulloblastoma 3 | 720
posterior fossa group A ependymoma 3 | 468
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Endocrine System 66 | 18,159
Digestive Tract 62 | 17,369
Nervous System 62 | 16,725
Blood and immune system 60 | 16,909
Female tissues 59 | 17,400
Skin and soft tissues 59 | 17,230
Male tissues 57 | 17,142
Urinary Tract 57 | 16,678
Liver and Pancreas 56 | 16,750
Respiratory system 56 | 16,393
Cardiovascular System 44 | 15,192

Target Family

Ion Channel 66 | 344
Kinase 1 | 634
Non-IDG 1 | 12,091

UniProt Keyword

Calcium channel 68 | 68
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transient receptor potential cation channel subfamily V member 2 TRPV2 Tchem Ion Channel -2.28525 197.9 203
Pannexin-1 PANX1 Tbio Ion Channel -2.59888 418.5 154
Calcium-activated chloride channel regulator family member 3 CLCA3P Tdark Ion Channel 0.00000 0
Transient receptor potential cation channel subfamily M member 2 TRPM2 Tchem Ion Channel -1.34318 25.1 209
Transient receptor potential cation channel subfamily M member 7 TRPM7 Tchem Ion Channel -2.53154 365.5 317
Voltage-dependent calcium channel gamma-like subunit TMEM37 Tbio Ion Channel -2.84704 668.1 56
Short transient receptor potential channel 7 TRPC7 Tchem Ion Channel -2.43775 199.8 220
Transient receptor potential cation channel subfamily M member 3 TRPM3 Tchem Ion Channel -2.19236 141.8 121
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.86016 747.3 258
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231