Development Level

Tbio 553 | 11,445
Tchem 143 | 1,598
Tdark 140 | 6,588
Tclin 39 | 613

Collection

RFA-RM-18-021 33 | 328
Ion Channel: IDG Consortium (T... 27 | 99
GPCR: IDG Consortium (Targets) 3 | 126
Kinase: IDG Consortium (Target... 3 | 125
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

preweaning lethality, incomple... 36 | 499
preweaning lethality, complete... 34 | 979
abnormal behavior 16 | 298
increased total body fat amoun... 15 | 134
increased lean body mass 14 | 172
decreased total body fat amoun... 13 | 207
decreased vertical activity 13 | 208
enlarged heart 12 | 210
decreased body weight 11 | 161
decreased bone mineral content 11 | 151
increased startle reflex 11 | 112
abnormal heart morphology 10 | 162
decreased bone mineral density 10 | 126
abnormal bone structure 9 | 187
abnormal seminal vesicle morph... 9 | 114
decreased lean body mass 9 | 135
embryonic lethality prior to t... 9 | 278
increased circulating alkaline... 9 | 122
decreased fasted circulating g... 8 | 65
decreased grip strength 8 | 116
decreased prepulse inhibition 8 | 82
hyperactivity 8 | 148
increased or absent threshold ... 8 | 101
short tibia 8 | 97
abnormal embryo size 7 | 220
abnormal gait 7 | 69
decreased circulating calcium ... 7 | 36
decreased circulating glucose ... 7 | 126
decreased startle reflex 7 | 75
hypoactivity 7 | 132
increased bone mineral content 7 | 108
increased circulating sodium l... 7 | 71
tremors 7 | 39
cataract 6 | 92
decreased body length 6 | 101
decreased circulating insulin ... 6 | 76
decreased lymphocyte cell numb... 6 | 83
impaired glucose tolerance 6 | 75
small superior vagus ganglion 6 | 74
abnormal eye morphology 5 | 68
abnormal sleep behavior 5 | 70
decreased circulating sodium l... 5 | 22
decreased mean corpuscular hem... 5 | 31
decreased mean corpuscular vol... 5 | 79
decreased neutrophil cell numb... 5 | 42
increased bone mineral density 5 | 72
increased circulating HDL chol... 5 | 80
increased circulating chloride... 5 | 41
increased circulating triglyce... 5 | 42
increased monocyte cell number 5 | 63
abnormal lens morphology 4 | 81
abnormal locomotor behavior 4 | 24
abnormal retina morphology 4 | 71
abnormal vibrissa morphology 4 | 25
absent startle reflex 4 | 24
cardiovascular system phenotyp... 4 | 36
decreased circulating HDL chol... 4 | 68
decreased circulating alkaline... 4 | 46
decreased circulating choleste... 4 | 93
decreased circulating triglyce... 4 | 79
edema 4 | 59
enlarged spleen 4 | 41
hydrometra 4 | 53
increased fasted circulating g... 4 | 76
limb grasping 4 | 41
male infertility 4 | 123
small thymus 4 | 16
abnormal coat appearance 3 | 31
abnormal coat-hair pigmentatio... 3 | 64
abnormal cornea morphology 3 | 31
abnormal cranium morphology 3 | 36
abnormal epididymis morphology 3 | 42
abnormal head morphology 3 | 10
abnormal kidney morphology 3 | 65
abnormal pancreas morphology 3 | 13
abnormal retinal vasculature m... 3 | 27
abnormal snout morphology 3 | 23
abnormal spleen morphology 3 | 55
abnormal tail morphology 3 | 25
brachydactyly 3 | 19
decreased circulating amylase ... 3 | 28
decreased circulating creatini... 3 | 39
decreased circulating free fat... 3 | 31
decreased circulating glycerol... 3 | 16
decreased circulating serum al... 3 | 82
decreased circulating total pr... 3 | 49
decreased erythrocyte cell num... 3 | 62
decreased heart rate variabili... 3 | 13
decreased heart weight 3 | 27
decreased leukocyte cell numbe... 3 | 73
decreased mean platelet volume 3 | 25
improved glucose tolerance 3 | 79
increased circulating choleste... 3 | 66
increased circulating creatini... 3 | 38
increased circulating total pr... 3 | 28
increased erythrocyte cell num... 3 | 39
increased heart weight 3 | 62
increased mean corpuscular hem... 3 | 96
mammalian phenotype 3 | 17
prolonged ST segment 3 | 36

Disease

Carcinoma 657 | 11,493
ovarian cancer 372 | 8,520
psoriasis 366 | 6,694
glioblastoma 350 | 5,792
osteosarcoma 343 | 7,950
medulloblastoma, large-cell 324 | 6,241
atypical teratoid / rhabdoid tumor 309 | 5,112
ependymoma 296 | 4,679
lung cancer 276 | 4,740
Kidney cancer 273 | 2,613
lung carcinoma 250 | 2,843
adult high grade glioma 240 | 3,801
Astrocytoma, Pilocytic 236 | 3,081
Breast cancer 232 | 3,578
group 3 medulloblastoma 226 | 4,104
oligodendroglioma 200 | 2,850
intraductal papillary-mucinous neoplasm (IPMN) 195 | 3,291
lung adenocarcinoma 192 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 190 | 2,955
primitive neuroectodermal tumor 188 | 3,035
non-small cell lung cancer 179 | 2,890
pancreatic cancer 177 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 175 | 2,989
invasive ductal carcinoma 173 | 2,951
malignant mesothelioma 163 | 3,232
astrocytic glioma 159 | 2,597
subependymal giant cell astrocytoma 151 | 2,287
interstitial cystitis 148 | 2,312
Cancer 140 | 2,499
pituitary cancer 132 | 1,972
cystic fibrosis 129 | 1,696
ulcerative colitis 120 | 1,819
Pick disease 115 | 1,894
group 4 medulloblastoma 113 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 109 | 1,962
colon cancer 106 | 1,478
Autosomal recessive predisposition 101 | 1,442
ductal carcinoma in situ 100 | 1,745
Melanoma 95 | 711
adrenocortical carcinoma 95 | 1,428
tuberculosis 93 | 2,010
Liver cancer 92 | 604
Schizophrenia 91 | 1,160
breast carcinoma 91 | 1,638
diabetes mellitus 87 | 1,728
primary pancreatic ductal adenocarcinoma 85 | 1,109
Skin cancer 82 | 469
nasopharyngeal carcinoma 71 | 1,058
Liver Cirrhosis, Experimental 69 | 769
Duchenne muscular dystrophy 68 | 601
active Crohn's disease 66 | 922
Bipolar Disorder 65 | 666
astrocytoma 65 | 1,146
Rheumatoid arthritis 64 | 1,191
esophageal adenocarcinoma 64 | 737
juvenile dermatomyositis 64 | 1,187
acute quadriplegic myopathy 63 | 1,158
cutaneous lupus erythematosus 63 | 1,057
gastric carcinoma 61 | 807
pediatric high grade glioma 61 | 1,064
Atopic dermatitis 60 | 952
Endometrial cancer 58 | 311
autosomal dominant Emery-Dreifuss muscular dystrophy 54 | 510
active ulcerative colitis 52 | 764
Epilepsy 51 | 792
Alzheimer's disease 50 | 658
non primary Sjogren syndrome sicca 50 | 891
Intellectual disability 49 | 1,016
dermatomyositis 49 | 966
aldosterone-producing adenoma 45 | 665
mucosa-associated lymphoid tissue lymphoma 44 | 484
Hypertension 43 | 396
Endometriosis 42 | 540
Down syndrome 39 | 499
medulloblastoma 38 | 720
spina bifida 38 | 1,074
Obesity 37 | 678
Vascular disease 37 | 319
Atherosclerosis 35 | 291
fibroadenoma 35 | 559
Asthma 33 | 385
Osteoporosis 33 | 363
non-small cell lung carcinoma 33 | 317
primary Sjogren syndrome 33 | 735
Prostatic Neoplasms 32 | 495
Multiple Sclerosis 31 | 540
Short stature 31 | 531
Becker muscular dystrophy 30 | 191
Dull intelligence 30 | 645
Heart disease 30 | 306
Kidney disease 30 | 430
Low intelligence 30 | 645
Mental Retardation 30 | 645
Mental deficiency 30 | 645
Poor school performance 30 | 645
sonic hedgehog group medulloblastoma 30 | 467
Amyotrophic lateral sclerosis 29 | 451
Hypertensive disease 29 | 292
Muscle hypotonia 29 | 571
urothelial carcinoma 29 | 318

Tissue

Endocrine System 846 | 18,159
Digestive Tract 829 | 17,369
Female tissues 822 | 17,400
Skin and soft tissues 818 | 17,230
Male tissues 805 | 17,142
Liver and Pancreas 798 | 16,750
Blood and immune system 796 | 16,909
Nervous System 791 | 16,725
Urinary Tract 790 | 16,678
Respiratory system 767 | 16,393
Cardiovascular System 684 | 15,192

Target Family

Non-IDG 523 | 12,091
Enzyme 204 | 4,145
Ion Channel 97 | 344
Transporter 23 | 473
Kinase 14 | 634
GPCR 13 | 408
Epigenetic 1 | 242

UniProt Keyword

Calcium 875 | 875
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein S100-A11 S100A11 Tbio Non-IDG -2.01412 110.0 311
Protocadherin gamma-A9 PCDHGA9 Tdark Non-IDG 0.51 0.72 31
Sorcin SRI Tbio Non-IDG -2.69915 481.5 119
N-terminal EF-hand calcium-binding protein 3 NECAB3 Tbio Non-IDG -0.72732 5.89 90
Tropomyosin alpha-4 chain TPM4 Tbio Non-IDG -1.57899 37.4 120
Cadherin-18 CDH18 Tdark Non-IDG -0.64897 4.11 125
Protocadherin beta-14 PCDHB14 Tdark Non-IDG 0.78 0.14 90
Protocadherin beta-12 PCDHB12 Tdark Non-IDG 0.00000 88
Protocadherin beta-13 PCDHB13 Tdark Non-IDG 0.00000 101
Protocadherin gamma-C4 PCDHGC4 Tdark Non-IDG 0.60 0.18 87