Development Level

Tchem 25 | 1,598
Tbio 13 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 9 | 979
decreased body weight 4 | 161
abnormal behavior 3 | 298
decreased total body fat amoun... 3 | 207
male infertility 3 | 123
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 93
increased lean body mass 2 | 172
increased mean platelet volume 2 | 45
abnormal QT variability 1 | 10
abnormal coat appearance 1 | 31
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal hindbrain morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal midbrain morphology 1 | 10
abnormal motor capabilities-co... 1 | 5
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal stomach morphology 1 | 10
decreased T cell number 1 | 15
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating glucose ... 1 | 126
decreased circulating magnesiu... 1 | 13
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased red blood cell distr... 1 | 41
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased blood uric acid leve... 1 | 5
increased circulating HDL chol... 1 | 80
increased exploration in new e... 1 | 8
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
long tibia 1 | 25
mammalian phenotype 1 | 17
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
small testis 1 | 58
tremors 1 | 39

Disease

Carcinoma 38 | 11,493
osteosarcoma 30 | 7,950
Kidney cancer 25 | 2,613
ovarian cancer 25 | 8,520
group 3 medulloblastoma 19 | 4,104
lung cancer 17 | 4,740
Cancer 16 | 2,499
glioblastoma 16 | 5,792
medulloblastoma, large-cell 16 | 6,241
Breast cancer 13 | 3,578
primitive neuroectodermal tumor 13 | 3,035
oligodendroglioma 12 | 2,850
Intellectual disability 11 | 1,016
atypical teratoid / rhabdoid tumor 11 | 5,112
psoriasis 11 | 6,694
Rheumatoid arthritis 10 | 1,191
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Liver cancer 9 | 604
ependymoma 9 | 4,679
juvenile dermatomyositis 9 | 1,187
adult high grade glioma 8 | 3,801
astrocytoma 8 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
malignant mesothelioma 8 | 3,232
subependymal giant cell astrocytoma 8 | 2,287
acute myeloid leukemia 7 | 783
Dull intelligence 6 | 645
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
Schizophrenia 6 | 1,160
Small head 6 | 374
dermatomyositis 6 | 966
invasive ductal carcinoma 6 | 2,951
spina bifida 6 | 1,074
Bipolar Disorder 5 | 666
Endometrial cancer 5 | 311
Lymphoid leukemia 5 | 160
Muscle hypotonia 5 | 571
Pick disease 5 | 1,894
Short stature 5 | 531
Strabismus 5 | 270
ductal carcinoma in situ 5 | 1,745
Adenoid Cystic Carcinoma 4 | 99
Astrocytoma, Pilocytic 4 | 3,081
Autistic Disorder 4 | 364
Bilateral fifth finger clinodactyly 4 | 110
Bladder Neoplasm 4 | 112
Broad flat nasal bridge 4 | 236
Bushy eyebrows 4 | 49
Carcinoma, Adenoid Cystic 4 | 99
Congenital Epicanthus 4 | 177
Cryptorchidism 4 | 296
Curvature of little finger 4 | 110
Delayed speech and language development 4 | 112
Epilepsy 4 | 792
Failure to gain weight 4 | 365
Immune system cancer 4 | 140
Language Delay 4 | 112
Large intestine cancer 4 | 126
Macrostomia 4 | 72
Multiple myeloma 4 | 1,332
Nasal bridge wide 4 | 236
Pediatric failure to thrive 4 | 365
Seizures 4 | 596
Small Cell Lung Carcinoma 4 | 41
Small cell carcinoma of lung 4 | 45
Speech Delay 4 | 112
Speech impairment 4 | 112
Urinary Bladder Neoplasms 4 | 114
Waldenstrons macroglobulinemia 4 | 765
astrocytic glioma 4 | 2,597
group 4 medulloblastoma 4 | 1,855
lung carcinoma 4 | 2,843
medulloblastoma 4 | 720
pituitary cancer 4 | 1,972
progressive supranuclear palsy 4 | 676
tuberculosis 4 | 2,010
tuberculosis and treatment for 6 months 4 | 409
ulcerative colitis 4 | 1,819
Acquired scoliosis 3 | 281
Aggressive behavior 3 | 75
Aggressive reaction 3 | 75
Byzanthine arch palate 3 | 194
Curvature of spine 3 | 282
Down syndrome 3 | 499
Long philtrum 3 | 137
Melanoma 3 | 711
Physical aggression 3 | 76
Prostatic Neoplasms 3 | 495
Skin cancer 3 | 469
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
atypical teratoid/rhabdoid tumor 3 | 357
interstitial cystitis 3 | 2,312
lung adenocarcinoma 3 | 2,716
pediatric high grade glioma 3 | 1,064

Tissue

Endocrine System 39 | 18,159
Blood and immune system 38 | 16,909
Digestive Tract 38 | 17,369
Female tissues 38 | 17,400
Liver and Pancreas 38 | 16,750
Male tissues 38 | 17,142
Nervous System 38 | 16,725
Respiratory system 38 | 16,393
Skin and soft tissues 38 | 17,230
Urinary Tract 38 | 16,678
Cardiovascular System 37 | 15,192

Target Family

Epigenetic 33 | 242
TF/Epigenetic 5 | 38
Kinase 1 | 634

UniProt Keyword

Bromodomain 39 | 39
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATPase family AAA domain-containing protein 2B ATAD2B Tchem Epigenetic 0.27 1.01 18
Bromodomain and PHD finger-containing protein 3 BRPF3 Tchem Epigenetic -0.46982 2.70 64
Tyrosine-protein kinase BAZ1B BAZ1B Tbio Epigenetic -1.45627 32.0 155
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Tchem TF/Epigenetic -2.07564 115.2 51
Protein polybromo-1 PBRM1 Tchem TF/Epigenetic -1.92500 84.6 97
Tripartite motif-containing protein 66 TRIM66 Tdark Epigenetic -0.11394 2.15 17
Transcription intermediary factor 1-alpha TRIM24 Tchem Epigenetic -2.15509 143.0 372
Cat eye syndrome critical region protein 2 CECR2 Tchem Epigenetic -2.17030 147.0 44
Nucleosome-remodeling factor subunit BPTF BPTF Tchem Epigenetic -1.77472 58.0 68
E3 ubiquitin-protein ligase TRIM33 TRIM33 Tbio Epigenetic -3.10754 1197.2 297