Development Level

Tbio 28 | 11,445
Tchem 12 | 1,598
Tclin 7 | 613

IMPC Phenotype

abnormal seminal vesicle morph... 2 | 114
decreased bone mineral content 2 | 151
enlarged heart 2 | 210
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal eye anterior chamber ... 1 | 9
abnormal snout morphology 1 | 23
abnormal testis morphology 1 | 43
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating phosphat... 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hydrometra 1 | 53
increased bone mineral content 1 | 108
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean platelet volume 1 | 45
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39

Disease

Carcinoma 38 | 11,493
ovarian cancer 24 | 8,520
Autosomal recessive predisposition 23 | 1,442
Cerebrovascular disease 21 | 238
lung cancer 21 | 4,740
Thrombophilia 20 | 38
Coronary artery disease 19 | 268
Cancer 18 | 2,499
lung carcinoma 17 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
Thrombosis 16 | 46
Venous Thrombosis 16 | 47
lung adenocarcinoma 16 | 2,716
Disseminated intravascular coagulation 15 | 38
Thrombocytopenia 15 | 197
atypical teratoid / rhabdoid tumor 15 | 5,112
pancreatic cancer 15 | 2,398
psoriasis 15 | 6,694
Atherosclerosis 14 | 291
Epistaxis 14 | 43
Hypertension 14 | 396
Pulmonary embolism 14 | 55
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
invasive ductal carcinoma 14 | 2,951
non-small cell lung cancer 14 | 2,890
Vascular disease 13 | 319
adult high grade glioma 13 | 3,801
osteosarcoma 13 | 7,950
Breast cancer 12 | 3,578
Protein C deficiency 12 | 19
diabetes mellitus 12 | 1,728
glioblastoma 12 | 5,792
tuberculosis 12 | 2,010
Menorrhagia 11 | 25
ependymoma 11 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
medulloblastoma, large-cell 11 | 6,241
Kidney disease 10 | 430
Purpura 10 | 43
Von Willebrand's disease 10 | 19
ductal carcinoma in situ 10 | 1,745
interstitial cystitis 10 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
Astrocytoma, Pilocytic 9 | 3,081
Ecchymosis 9 | 66
Hemarthrosis 9 | 12
Hemophilia B 9 | 11
Increased tendency to bruise 9 | 66
Liver Cirrhosis, Experimental 9 | 769
Liver disease 9 | 237
breast carcinoma 9 | 1,638
cystic fibrosis 9 | 1,696
group 3 medulloblastoma 9 | 4,104
primitive neuroectodermal tumor 9 | 3,035
Bernard-Soulier syndrome 8 | 14
Bleeding tendency 8 | 37
Congenital afibrinogenemia 8 | 11
Factor XI Deficiency 8 | 12
Glanzmann's thrombasthenia 8 | 23
Heart disease 8 | 306
Hypertensive disease 8 | 292
Partial thromboplastin time increased (finding) 8 | 11
Thrombophlebitis 8 | 19
malignant mesothelioma 8 | 3,232
pituitary cancer 8 | 1,972
ulcerative colitis 8 | 1,819
Anemia 7 | 365
Bleeding time prolonged 7 | 31
Deep Vein Thrombosis 7 | 8
Factor XII deficiency 7 | 13
Hemorrhage 7 | 19
Hypersensitivity reaction type II disease 7 | 253
Kidney cancer 7 | 2,613
Liver Cirrhosis 7 | 181
Myocardial Infarction 7 | 151
Peripheral vascular disease 7 | 87
Thromboembolism 7 | 15
pancreatic carcinoma 7 | 562
Blood protein disease 6 | 11
Chemical and Drug Induced Liver Injury 6 | 195
Decreased platelet count 6 | 111
Factor VII Deficiency 6 | 7
Factor VIII deficiency 6 | 10
Gastrointestinal Hemorrhage 6 | 52
Gingival Hemorrhage 6 | 18
Hepatic veno-occlusive disease 6 | 16
Highly variable severity 6 | 157
Placental abruption 6 | 18
Stomach Neoplasms 6 | 300
Variable expressivity 6 | 157
Vasculitis 6 | 80
Venous Thromboembolism 6 | 8
gastric carcinoma 6 | 807
Duchenne muscular dystrophy 5 | 601
acute quadriplegic myopathy 5 | 1,158
adrenocortical carcinoma 5 | 1,428
colon cancer 5 | 1,478
mucosa-associated lymphoid tissue lymphoma 5 | 484
nephrosclerosis 5 | 333
oligodendroglioma 5 | 2,850

Tissue

Digestive Tract 46 | 17,369
Endocrine System 45 | 18,159
Liver and Pancreas 45 | 16,750
Urinary Tract 45 | 16,678
Female tissues 43 | 17,400
Skin and soft tissues 43 | 17,230
Male tissues 42 | 17,142
Blood and immune system 41 | 16,909
Respiratory system 40 | 16,393
Nervous System 38 | 16,725
Cardiovascular System 32 | 15,192

Target Family

Non-IDG 25 | 12,091
Enzyme 17 | 4,145
GPCR 5 | 408

UniProt Keyword

Blood coagulation 47 | 47
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteinase-activated receptor 4 F2RL3 Tchem GPCR -1.50044 34.1 276
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
Coagulation factor V F5 Tbio Non-IDG -2.73955 525.3 198
Bis(5'-adenosyl)-triphosphatase ENPP4 ENPP4 Tbio Enzyme -0.71154 4.27 88
Platelet glycoprotein V GP5 Tbio Non-IDG -2.81536 644.5 88
Platelet glycoprotein Ib beta chain GP1BB Tbio Non-IDG -1.79873 57.4 87
Fibrinogen alpha chain FGA Tbio Non-IDG -2.88066 753.1 595
Fibrinogen gamma chain FGG Tbio Non-IDG -2.21041 158.7 384
Endothelial protein C receptor PROCR Tbio Non-IDG -2.70271 541.0 367
Proteinase-activated receptor 1 F2R Tclin GPCR -2.78393 551.0 453