Development Level

Tbio 29 | 11,178
Tchem 3 | 1,885

IMPC Phenotype

abnormal seminal vesicle morph... 4 | 114
abnormal kidney morphology 3 | 65
improved glucose tolerance 3 | 79
decreased circulating calcium ... 2 | 36
decreased mean corpuscular vol... 2 | 79
preweaning lethality, incomple... 2 | 499
prolonged ST segment 2 | 36
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal eyelid morphology 1 | 7
abnormal femur morphology 1 | 14
abnormal joint morphology 1 | 23
abnormal radius morphology 1 | 8
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
abnormal vibrissa morphology 1 | 25
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased heart rate 1 | 18
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged kidney 1 | 14
enlarged uterus 1 | 11
hydrometra 1 | 53
increased circulating alkaline... 1 | 122
increased circulating potassiu... 1 | 29
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
long tail 1 | 1
mammalian phenotype 1 | 17
narrow eye opening 1 | 12
polycystic kidney 1 | 15
prolonged PR interval 1 | 15
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58
thick tail 1 | 1

Disease

Carcinoma 17 | 11,192
ovarian cancer 14 | 8,297
pancreatic cancer 12 | 2,322
psoriasis 12 | 6,514
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,204
invasive ductal carcinoma 10 | 2,867
Amelogenesis imperfecta 9 | 26
Dental caries 9 | 157
Rickets 9 | 46
medulloblastoma, large-cell 9 | 6,086
non-small cell lung cancer 9 | 2,799
Autosomal recessive predisposition 8 | 1,407
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,902
Breast cancer 7 | 3,469
Osteomalacia 7 | 33
adult high grade glioma 7 | 3,701
glioblastoma 7 | 5,635
interstitial cystitis 7 | 2,237
ulcerative colitis 7 | 1,765
Dentinogenesis imperfecta 6 | 21
atypical teratoid / rhabdoid tumor 6 | 4,971
lung cancer 6 | 4,607
osteosarcoma 6 | 7,766
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,911
Ameloblastoma 5 | 21
Ankylosis 5 | 28
Astrocytoma, Pilocytic 5 | 3,006
Craniosynostosis 5 | 73
Dental Enamel Hypoplasia 5 | 42
Dental fluorosis 5 | 18
Dentin dysplasia 5 | 15
Hypophosphatemia 5 | 38
Kidney cancer 5 | 2,548
breast carcinoma 5 | 1,589
cystic fibrosis 5 | 1,629
gastric carcinoma 5 | 781
lung carcinoma 5 | 2,755
primary pancreatic ductal adenocarcinoma 5 | 1,071
Calcinosis 4 | 63
Cancer 4 | 2,388
Hyperphosphatemia 4 | 29
Osteoporosis 4 | 348
diabetes mellitus 4 | 1,683
ductal carcinoma in situ 4 | 1,686
group 4 medulloblastoma 4 | 1,806
lung adenocarcinoma 4 | 2,627
pituitary cancer 4 | 1,915
Duchenne muscular dystrophy 3 | 587
Endometriosis 3 | 521
Genu varum 3 | 26
Hypercementosis 3 | 5
Hypertension 3 | 372
Hypophosphatasia 3 | 10
Kidney disease 3 | 411
Late tooth eruption 3 | 59
Nephrocalcinosis 3 | 34
Obesity 3 | 655
Osteoarthritis 3 | 179
Osteogenesis imperfecta 3 | 31
Osteosclerosis 3 | 30
Periodontal disease 3 | 35
Short stature 3 | 514
Skull malformation 3 | 37
Tooth erosion 3 | 4
adrenocortical carcinoma 3 | 1,385
cutaneous lupus erythematosus 3 | 1,016
ependymoma 3 | 4,559
esophageal adenocarcinoma 3 | 696
malignant mesothelioma 3 | 3,135
tuberculosis 3 | 1,963
Abnormal skeletal development 2 | 60
Abnormal trabecular bone morphology 2 | 6
Atherosclerosis 2 | 276
Autistic Disorder 2 | 358
Bone pain 2 | 40
Breast Neoplasms 2 | 423
Craniofacial Abnormalities 2 | 141
Gingival Overgrowth 2 | 33
Heart valve disease 2 | 38
Hypercalcemia 2 | 57
Kidney Diseases 2 | 110
Klinefelter's syndrome 2 | 55
Liver Cirrhosis, Experimental 2 | 733
Liver disease 2 | 227
Lytic lesion 2 | 32
Malabsorption 2 | 81
Mammary Neoplasms 2 | 403
Neoplasm Metastasis 2 | 160
Osteochondrodysplasias 2 | 72
Osteomyelitis 2 | 42
Parietal foramina 2 | 10
Recurrent respiratory infections 2 | 138
Root resorption 2 | 22
Seizures 2 | 584
Sensorineural Hearing Loss (disorder) 2 | 281
Turner syndrome 2 | 24
interstitial lung disease 2 | 287
medulloblastoma 2 | 702
sarcoidosis 2 | 357

Tissue

Endocrine System 30 | 18,159
Blood and immune system 27 | 16,909
Digestive Tract 27 | 17,369
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Skin and soft tissues 26 | 17,230
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Urinary Tract 22 | 16,678
Cardiovascular System 21 | 15,192

Target Family

Non-IDG 26 | 12,091
Enzyme 6 | 4,145

UniProt Keyword

Biomineralization 32 | 32
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bone sialoprotein 2 IBSP Tbio Non-IDG -2.95483 756.8 261
Dentin matrix acidic phosphoprotein 1 DMP1 Tbio Non-IDG -1.66811 45.5 231
Tuftelin-interacting protein 11 TFIP11 Tbio Non-IDG -1.75990 66.6 84
Enamelin ENAM Tbio Non-IDG -2.25637 174.2 73
Amelogenin, X isoform AMELX Tbio Non-IDG -2.84702 695.0 136
Amelogenin, Y isoform AMELY Tbio Non-IDG -2.86429 712.3 22
Otopetrin-1 OTOP1 Tbio Non-IDG -1.03625 9.73 55
Asporin ASPN Tbio Non-IDG -2.64447 408.2 128
Statherin STATH Tbio Non-IDG -2.16867 156.5 38
Metal transporter CNNM4 CNNM4 Tbio Non-IDG -1.18531 16.5 123