Development Level

Tbio 72 | 11,445
Tchem 41 | 1,598
Tclin 9 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 12 | 979
abnormal behavior 5 | 298
decreased total body fat amoun... 5 | 207
embryonic lethality prior to t... 5 | 278
abnormal bone structure 4 | 187
enlarged heart 4 | 210
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
decreased body length 3 | 101
decreased lean body mass 3 | 135
improved glucose tolerance 3 | 79
increased circulating triglyce... 3 | 42
increased lean body mass 3 | 172
increased mean corpuscular vol... 3 | 92
preweaning lethality, incomple... 3 | 499
abnormal bone mineralization 2 | 38
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating alkaline... 2 | 46
decreased fasted circulating g... 2 | 65
decreased lymphocyte cell numb... 2 | 83
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
enlarged spleen 2 | 41
increased body length 2 | 32
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating calcium ... 2 | 34
increased hematocrit 2 | 46
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
increased total body fat amoun... 2 | 134
mammalian phenotype 2 | 17
abnormal brain morphology 1 | 13
abnormal cecum morphology 1 | 7
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal forebrain development 1 | 20
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain development 1 | 16
abnormal iris morphology 1 | 13
abnormal locomotor activation 1 | 16
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pupil morphology 1 | 2
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 36
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating insulin ... 1 | 76
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
hydroencephaly 1 | 14
hyperactivity 1 | 148
increased B cell number 1 | 9
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
limb grasping 1 | 41
male infertility 1 | 123
microphthalmia 1 | 26
pale yolk sac 1 | 25
small testis 1 | 58
small thymus 1 | 16
thin ventricular wall 1 | 24
tremors 1 | 39

Disease

Carcinoma 97 | 11,493
ovarian cancer 82 | 8,520
osteosarcoma 77 | 7,950
psoriasis 69 | 6,694
medulloblastoma, large-cell 66 | 6,241
glioblastoma 63 | 5,792
atypical teratoid / rhabdoid tumor 59 | 5,112
lung cancer 56 | 4,740
Cancer 55 | 2,499
group 3 medulloblastoma 48 | 4,104
ependymoma 46 | 4,679
primitive neuroectodermal tumor 44 | 3,035
Breast cancer 40 | 3,578
adult high grade glioma 40 | 3,801
oligodendroglioma 37 | 2,850
non-small cell lung cancer 36 | 2,890
Schizophrenia 35 | 1,160
intraductal papillary-mucinous neoplasm (IPMN) 35 | 3,291
astrocytic glioma 34 | 2,597
malignant mesothelioma 33 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,955
invasive ductal carcinoma 32 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,989
Kidney cancer 29 | 2,613
Bipolar Disorder 28 | 666
Astrocytoma, Pilocytic 27 | 3,081
lung adenocarcinoma 26 | 2,716
colon cancer 25 | 1,478
pituitary cancer 25 | 1,972
subependymal giant cell astrocytoma 25 | 2,287
diabetes mellitus 24 | 1,728
Pick disease 23 | 1,894
interstitial cystitis 23 | 2,312
ductal carcinoma in situ 22 | 1,745
pancreatic cancer 22 | 2,398
Obesity 21 | 678
adrenocortical carcinoma 21 | 1,428
ulcerative colitis 20 | 1,819
Depressive disorder 19 | 409
Mental Depression 19 | 333
breast carcinoma 19 | 1,638
group 4 medulloblastoma 19 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
Rheumatoid arthritis 18 | 1,191
spina bifida 18 | 1,074
tuberculosis 18 | 2,010
Intellectual disability 17 | 1,016
Multiple myeloma 17 | 1,332
astrocytoma 17 | 1,146
lung carcinoma 17 | 2,843
acute quadriplegic myopathy 15 | 1,158
Mood Disorders 14 | 184
Epilepsy 13 | 792
Prostatic Neoplasms 13 | 495
Waldenstrons macroglobulinemia 13 | 765
cystic fibrosis 13 | 1,696
Alzheimer's disease 12 | 658
Atopic dermatitis 12 | 952
Autistic Disorder 12 | 364
aldosterone-producing adenoma 12 | 665
pediatric high grade glioma 12 | 1,064
Seasonal affective disorder 11 | 28
juvenile dermatomyositis 11 | 1,187
nasopharyngeal carcinoma 11 | 1,058
primary pancreatic ductal adenocarcinoma 11 | 1,109
Amyotrophic lateral sclerosis 10 | 451
Dull intelligence 10 | 645
Endometriosis 10 | 540
Low intelligence 10 | 645
Major Depressive Disorder 10 | 301
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Poor school performance 10 | 645
acute myeloid leukemia 10 | 783
dermatomyositis 10 | 966
hepatocellular carcinoma 10 | 547
Breast Neoplasms 9 | 445
Delayed speech and language development 9 | 112
Hyperglycemia 9 | 137
Language Delay 9 | 112
Mammary Neoplasms 9 | 425
Muscle hypotonia 9 | 571
Speech Delay 9 | 112
Speech impairment 9 | 112
Stomach Neoplasms 9 | 300
Strabismus 9 | 270
cutaneous lupus erythematosus 9 | 1,057
medulloblastoma 9 | 720
Alcoholic Intoxication, Chronic 8 | 289
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Mental and motor retardation 8 | 608
Neoplasm Metastasis 8 | 168
Parkinson's disease 8 | 392
Seizures 8 | 596
Short stature 8 | 531
Unipolar Depression 8 | 250
active ulcerative colitis 8 | 764
chronic rhinosinusitis 8 | 512
esophageal adenocarcinoma 8 | 737

Tissue

Endocrine System 123 | 18,159
Digestive Tract 121 | 17,369
Female tissues 121 | 17,400
Skin and soft tissues 121 | 17,230
Blood and immune system 120 | 16,909
Nervous System 119 | 16,725
Liver and Pancreas 118 | 16,750
Male tissues 118 | 17,142
Respiratory system 118 | 16,393
Cardiovascular System 117 | 15,192
Urinary Tract 117 | 16,678

Target Family

Non-IDG 36 | 12,091
Transcription Factor 27 | 1,400
Enzyme 18 | 4,145
Kinase 14 | 634
Epigenetic 13 | 242
Nuclear Receptor 7 | 48
GPCR 5 | 408
TF/Epigenetic 4 | 38

UniProt Keyword

Biological rhythms 124 | 124
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Probable ATP-dependent RNA helicase DDX5 DDX5 Tbio Enzyme -2.08566 121.1 344
Melanoma-associated antigen D1 MAGED1 Tbio Non-IDG -1.55131 46.3 245
MAGE-like protein 2 MAGEL2 Tbio Non-IDG -1.95242 83.8 86
N6-adenosine-methyltransferase catalytic subunit METTL3 Tbio Enzyme -1.76174 60.5 94
Lysine-specific demethylase 5C KDM5C Tchem TF/Epigenetic -1.94004 86.4 135
Thyroid hormone receptor-associated protein 3 THRAP3 Tbio Non-IDG -0.87769 8.81 136
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.33813 207.8 169
Melanocortin receptor 3 MC3R Tchem GPCR -2.65556 445.3 202
D site-binding protein DBP Tbio Transcription Factor -1.50821 28.6 93