Development Level

Tbio 30 | 11,445
Tchem 16 | 1,598
Tdark 10 | 6,588
Tclin 1 | 613

Collection

Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to t... 2 | 278
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
abnormal behavior 1 | 298
abnormal placement of pupils 1 | 6
abnormal seminal vesicle morph... 1 | 114
abnormal vibrissa morphology 1 | 25
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Carcinoma 38 | 11,493
psoriasis 24 | 6,694
ovarian cancer 20 | 8,520
osteosarcoma 19 | 7,950
lung cancer 18 | 4,740
Kidney cancer 15 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
Cancer 14 | 2,499
Breast cancer 13 | 3,578
atypical teratoid / rhabdoid tumor 13 | 5,112
glioblastoma 13 | 5,792
interstitial cystitis 13 | 2,312
malignant mesothelioma 13 | 3,232
non-small cell lung cancer 13 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
lung adenocarcinoma 12 | 2,716
medulloblastoma, large-cell 12 | 6,241
pancreatic cancer 12 | 2,398
active ulcerative colitis 11 | 764
cystic fibrosis 11 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
ependymoma 10 | 4,679
group 3 medulloblastoma 10 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
lung carcinoma 10 | 2,843
oligodendroglioma 9 | 2,850
Autosomal recessive predisposition 8 | 1,442
active Crohn's disease 8 | 922
adult high grade glioma 8 | 3,801
esophageal adenocarcinoma 8 | 737
nasopharyngeal carcinoma 8 | 1,058
Atopic dermatitis 7 | 952
colon cancer 7 | 1,478
pediatric high grade glioma 7 | 1,064
Astrocytoma, Pilocytic 6 | 3,081
invasive ductal carcinoma 6 | 2,951
pituitary cancer 6 | 1,972
spina bifida 6 | 1,074
subependymal giant cell astrocytoma 6 | 2,287
ulcerative colitis 6 | 1,819
Coronary artery disease 5 | 268
Dull intelligence 5 | 645
Heart disease 5 | 306
Intellectual disability 5 | 1,016
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Pick disease 5 | 1,894
Poor school performance 5 | 645
Short stature 5 | 531
astrocytic glioma 5 | 2,597
breast carcinoma 5 | 1,638
diabetes mellitus 5 | 1,728
interstitial lung disease 5 | 298
primitive neuroectodermal tumor 5 | 3,035
tuberculosis 5 | 2,010
Anemia 4 | 365
Atherosclerosis 4 | 291
Cerebrovascular disease 4 | 238
Down syndrome 4 | 499
Epilepsy 4 | 792
Hypertension 4 | 396
Liver Cirrhosis, Experimental 4 | 769
Neurodegenerative disease 4 | 414
Prostatic Neoplasms 4 | 495
Small head 4 | 374
cutaneous lupus erythematosus 4 | 1,057
ductal carcinoma in situ 4 | 1,745
progressive supranuclear palsy 4 | 676
Acquired scoliosis 3 | 281
Alzheimer's disease 3 | 658
Arthritis 3 | 290
Bilateral fifth finger clinodactyly 3 | 110
Brachycephaly 3 | 88
Broad cranium shape 3 | 88
Carcinoma, Hepatocellular 3 | 228
Cerebral atrophy 3 | 178
Craniofacial Abnormalities 3 | 151
Curvature of little finger 3 | 110
Curvature of spine 3 | 282
Delayed speech and language development 3 | 112
Endometriosis 3 | 540
Hypogonadism 3 | 173
Infantile onset 3 | 238
Kidney disease 3 | 430
Language Delay 3 | 112
Liver carcinoma 3 | 240
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
Netherton syndrome 3 | 15
Orbital separation excessive 3 | 244
Osteoporosis 3 | 363
Parkinson's disease 3 | 392
Seizures 3 | 596
Speech Delay 3 | 112
Speech impairment 3 | 112
Wide skull shape 3 | 88
X-linked cerebral adrenoleukodystrophy 3 | 116
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428

Tissue

Digestive Tract 46 | 17,369
Endocrine System 46 | 18,159
Urinary Tract 46 | 16,678
Female tissues 45 | 17,400
Liver and Pancreas 45 | 16,750
Male tissues 45 | 17,142
Nervous System 45 | 16,725
Skin and soft tissues 45 | 17,230
Blood and immune system 42 | 16,909
Respiratory system 41 | 16,393
Cardiovascular System 32 | 15,192

Target Family

Enzyme 38 | 4,145
Non-IDG 13 | 12,091
Ion Channel 3 | 344
GPCR 2 | 408
Transcription Factor 1 | 1,400

UniProt Keyword

Autocatalytic cleavage 57 | 57
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-secretase 2 BACE2 Tchem Enzyme -2.09709 114.0 418
Endogenous retrovirus group K member 6 Pro protein ERVK-6 Tdark Enzyme 0.00000 0
Atrial natriuretic peptide-converting enzyme CORIN Tbio Non-IDG -2.14443 144.4 221
Mucin-2 MUC2 Tbio Non-IDG -2.89417 752.2 0
Adhesion G protein-coupled receptor E2 ADGRE2 Tbio GPCR -1.67862 48.2 312
S-adenosylmethionine decarboxylase proenzyme AMD1 Tchem Enzyme -3.21826 1586.8 141
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.60032 392.5 519
Endogenous retrovirus group K member 9 Pro protein ERVK-9 Tdark Enzyme 0.00000 0
Endogenous retrovirus group K member 24 Pro protein ERVK-24 Tdark Enzyme 0.00000 0
Endogenous retrovirus group K member 25 Pro protein ERVK-25 Tdark Enzyme 0.00000 0