Development Level

Tdark 13 | 6,588
Tchem 5 | 1,598
Tbio 4 | 11,445
Tclin 2 | 613

IMPC Phenotype

premature death 1 | 5
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 7 | 11,493
lung cancer 5 | 4,740
Cancer 4 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung carcinoma 4 | 2,843
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis type 3 3 | 17
diabetes mellitus 3 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
medulloblastoma, large-cell 3 | 6,241
non-small cell lung cancer 3 | 2,890
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
pancreatic cancer 3 | 2,398
psoriasis 3 | 6,694
subependymal giant cell astrocytoma 3 | 2,287
Amyotrophic lateral sclerosis type 1 2 | 23
Autosomal recessive predisposition 2 | 1,442
Down syndrome 2 | 499
Kidney Diseases 2 | 114
Small head 2 | 374
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
breast carcinoma 2 | 1,638
glioblastoma 2 | 5,792
interstitial cystitis 2 | 2,312
interstitial lung disease 2 | 298
malignant mesothelioma 2 | 3,232
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Abnormal vision 1 | 52
Achromatopsia 1 | 16
Adrenal cortical adenoma 1 | 19
Albuminuria 1 | 21
Amyloidosis 1 | 67
Angioedema 1 | 38
Atrophic gastritis 1 | 5
Autonomic neuropathy 1 | 22
Autosomal dominant polycystic kidney disease 1 | 31
Barrett's esophagus 1 | 182
Bartter Syndrome 1 | 4
Bartter disease 1 | 13
Brain disease 1 | 96
CD40 deficiency 1 | 4
Carcinoma, Renal Cell 1 | 124
Cardiomegaly 1 | 116
Chemical and Drug Induced Liver Injury 1 | 195
Chronic Kidney Diseases 1 | 13
Congenital hypoplasia of kidney 1 | 32
Conn's syndrome 1 | 22
Diabetes Mellitus, Experimental 1 | 108
Diabetic retinopathy 1 | 56
Drug-Related Side Effects and Adverse Reactions 1 | 62
Esophagitis 1 | 35
Fibrosis 1 | 44
Gastritis 1 | 47
Hemorrhage 1 | 19
Hyperaldosteronism 1 | 35
Hyperglycemia 1 | 137
Hyperinsulinism 1 | 133
Hyperparathyroidism 1 | 48
Hypertensive Retinopathy 1 | 14
Hypertensive disorder 1 | 56
Hyperthyroidism 1 | 53
Hypertrophy, Left Ventricular 1 | 24
Hyperuricemia 1 | 49
Hypokalemia 1 | 52
Hypotension 1 | 82
Increased neuronal autofluorescent lipopigment 1 | 7
Ischemia 1 | 28
Lateral sclerosis 1 | 15
Left Ventricular Hypertrophy 1 | 47
Liddle syndrome 1 | 14
Mental deterioration 1 | 32
Metabolic acidosis 1 | 90
Muscle Rigidity 1 | 49
Myocardial Infarction 1 | 151
Nephrosis 1 | 21
Neuronal ceroid lipofuscinosis 1 | 28
Neuronal lipopigments 1 | 7
Obstructive sleep apnea 1 | 26
Ovarian hyperstimulation syndrome 1 | 19
Peripartum cardiomyopathy 1 | 4
Portal hypertension 1 | 20
Potter's facies 1 | 10
Progressive mental retardation 1 | 37
Progressive renal failure 1 | 13
Renal Cell Carcinoma 1 | 214
Sensory peripheral neuropathy 1 | 10
Substance Withdrawal Syndrome 1 | 55
Tubular atrophy 1 | 10
Ureteral obstruction 1 | 33
Vesicoureteral reflux 1 | 32
Weight Gain 1 | 100
inclusion-cell disease 1 | 16
pseudo-Hurler polydystrophy 1 | 6
sarcoidosis 1 | 370

Tissue

Endocrine System 12 | 18,159
Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Cardiovascular System 7 | 15,192

Target Family

Enzyme 23 | 4,145
Non-IDG 1 | 12,091

UniProt Keyword

Aspartyl protease 24 | 24
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

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