Development Level

Tbio 356 | 10,625
Tchem 128 | 1,890
Tdark 30 | 7,003
Tclin 15 | 602

Collection

Eligible Kinase Proteins 10 | 134

IMPC Term

preweaning lethality, complete... 18 | 633
decreased lean body mass 10 | 195
preweaning lethality, incomple... 10 | 260
abnormal behavior 7 | 226
abnormal bone structure 7 | 131
decreased grip strength 7 | 123
decreased bone mineral content 6 | 157
decreased bone mineral density 6 | 126
hypoactivity 6 | 89
increased circulating alkaline... 6 | 119
thrombocytopenia 6 | 46
abnormal bone mineralization 5 | 55
abnormal embryo size 5 | 112
abnormal retina morphology 5 | 100
decreased T cell number 5 | 31
decreased body weight 5 | 174
decreased total body fat amoun... 5 | 186
embryonic lethality prior to t... 5 | 187
enlarged heart 5 | 111
abnormal gait 4 | 51
abnormal lens morphology 4 | 73
decreased mean corpuscular hem... 4 | 34
decreased mean corpuscular vol... 4 | 50
increased grip strength 4 | 83
increased leukocyte cell numbe... 4 | 37
increased mean corpuscular vol... 4 | 91
tremors 4 | 34
abnormal coat/hair pigmentatio... 3 | 54
abnormal maxilla morphology 3 | 16
abnormal retinal pigmentation 3 | 61
abnormal tooth morphology 3 | 24
decreased circulating bilirubi... 3 | 14
decreased circulating choleste... 3 | 85
decreased circulating creatini... 3 | 31
decreased circulating glucose ... 3 | 121
decreased erythrocyte cell num... 3 | 43
decreased lumbar vertebrae num... 3 | 62
decreased prepulse inhibition 3 | 52
decreased rib number 3 | 59
embryonic lethality prior to o... 3 | 148
hydrops fetalis 3 | 22
hyperactivity 3 | 108
increased blood urea nitrogen ... 3 | 44
increased circulating choleste... 3 | 53
increased circulating sodium l... 3 | 71
increased or absent threshold ... 3 | 128
increased sacral vertebrae num... 3 | 62
limb grasping 3 | 35
prenatal lethality prior to he... 3 | 64
short tibia 3 | 82
abnormal behavioral response t... 2 | 52
abnormal cranium morphology 2 | 32
abnormal forebrain development 2 | 18
abnormal hindbrain development 2 | 24
abnormal limb bud morphology 2 | 15
abnormal limb morphology 2 | 7
abnormal locomotor activation 2 | 26
abnormal midbrain development 2 | 22
abnormal neural tube closure 2 | 37
abnormal respiratory quotient 2 | 9
abnormal seminal vesicle morph... 2 | 47
abnormal snout morphology 2 | 18
abnormal tail morphology 2 | 17
cyanosis 2 | 6
decreased CD8-positive, alpha-... 2 | 26
decreased IgG1 level 2 | 4
decreased NK T cell number 2 | 28
decreased body length 2 | 108
decreased circulating HDL chol... 2 | 77
decreased circulating alkaline... 2 | 41
decreased circulating potassiu... 2 | 17
decreased circulating triglyce... 2 | 83
decreased eosinophil cell numb... 2 | 41
decreased fasted circulating g... 2 | 49
decreased granulocyte number 2 | 8
decreased hematocrit 2 | 25
decreased lymphocyte cell numb... 2 | 9
decreased mature B cell number 2 | 25
decreased startle reflex 2 | 48
hemorrhage 2 | 12
increased Ly6C low monocyte nu... 2 | 8
increased circulating amylase ... 2 | 13
increased circulating calcium ... 2 | 32
increased circulating free fat... 2 | 17
increased effector memory CD4-... 2 | 15
increased heart weight 2 | 37
increased hemoglobin content 2 | 45
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
increased mean corpuscular hem... 2 | 25
male infertility 2 | 62
small superior vagus ganglion 2 | 20
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal tail movements 1 | 12
corneal opacity 1 | 25
decreased circulating magnesiu... 1 | 11
embryonic growth retardation 1 | 28
female infertility 1 | 34
increased circulating magnesiu... 1 | 10

Disease

ovarian cancer 312 | 8,484
osteosarcoma 252 | 7,933
psoriasis 228 | 6,685
medulloblastoma, large-cell 206 | 6,234
glioblastoma 203 | 5,572
Cancer 199 | 2,346
lung cancer 198 | 4,466
atypical teratoid / rhabdoid tumor 132 | 4,369
malignant mesothelioma 128 | 3,162
intraductal papillary-mucinous neoplasm (IPMN) 120 | 3,289
non-small cell lung cancer 119 | 2,798
Breast cancer 114 | 3,094
invasive ductal carcinoma 114 | 2,950
lung carcinoma 113 | 2,844
intraductal papillary-mucinous carcinoma (IPMC) 111 | 2,988
pilocytic astrocytoma 108 | 3,086
lung adenocarcinoma 107 | 2,713
pancreatic cancer 107 | 2,300
pediatric high grade glioma 105 | 2,712
oligodendroglioma 99 | 2,849
subependymal giant cell astrocytoma 98 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 95 | 2,956
primitive neuroectodermal tumor 95 | 3,031
ulcerative colitis 90 | 2,087
interstitial cystitis 88 | 2,299
pituitary cancer 82 | 1,972
group 3 medulloblastoma 74 | 2,254
tuberculosis 74 | 1,557
pancreatic ductal adenocarcinoma liver metastasis 72 | 1,795
astrocytic glioma 71 | 2,241
breast carcinoma 71 | 1,614
diabetes mellitus 70 | 1,663
ependymoma 70 | 2,514
Multiple myeloma 68 | 1,327
group 4 medulloblastoma 67 | 1,875
Pick disease 65 | 1,893
cystic fibrosis 64 | 1,665
ductal carcinoma in situ 63 | 1,745
adult high grade glioma 60 | 2,148
colon cancer 60 | 1,475
cutaneous lupus erythematosus 59 | 1,056
posterior fossa group A ependymoma 57 | 1,511
Carcinoma 56 | 2,147
adrenocortical carcinoma 56 | 1,427
primary pancreatic ductal adenocarcinoma 55 | 1,271
sonic hedgehog group medulloblastoma 53 | 1,482
astrocytoma 52 | 1,493
juvenile dermatomyositis 50 | 1,189
Alzheimer's disease 47 | 644
Rheumatoid Arthritis 47 | 1,160
medulloblastoma 46 | 1,524
dermatomyositis 45 | 933
nasopharyngeal carcinoma 45 | 1,056
spina bifida 45 | 1,064
acute quadriplegic myopathy 44 | 1,157
Waldenstrons macroglobulinemia 42 | 765
esophageal adenocarcinoma 42 | 737
primary Sjogren syndrome 42 | 789
active Crohn's disease 40 | 918
atypical teratoid/rhabdoid tumor 40 | 1,095
posterior fossa group B ependymoma 40 | 1,530
aldosterone-producing adenoma 39 | 664
gastric carcinoma 39 | 832
Vascular disease 38 | 281
Prostatic Neoplasms 35 | 471
Mammary Neoplasms 33 | 410
Atopic dermatitis 30 | 944
IGA Glomerulonephritis 29 | 454
acute myeloid leukemia 29 | 780
Lung Neoplasms 28 | 171
non primary Sjogren syndrome sicca 28 | 840
pancreatic carcinoma 28 | 567
Neurodegenerative disease 27 | 383
Obesity 27 | 616
Down syndrome 26 | 548
Kidney disease 25 | 396
hepatocellular carcinoma 25 | 532
non-small cell lung carcinoma 25 | 413
Multiple Sclerosis 24 | 498
active ulcerative colitis 23 | 477
tuberculosis and treatment for 6 months 23 | 686
Stomach Neoplasms 22 | 282
gastric cancer 22 | 430
Amyotrophic Lateral Sclerosis 21 | 431
Duchenne muscular dystrophy 21 | 602
Renal Cell Carcinoma 21 | 199
sarcoidosis 21 | 358
Parkinson's disease 20 | 364
fibroadenoma 20 | 557
mucosa-associated lymphoid tissue lymphoma 20 | 480
progressive supranuclear palsy 20 | 674
Melanoma 19 | 261
Adenocarcinoma 18 | 115
Colonic Neoplasms 17 | 126
Colorectal Neoplasms 17 | 217
Endometriosis 17 | 535
Toxic encephalopathy 17 | 131
Crohn's disease 16 | 304
Schizophrenia 16 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 16 | 499

Tissue

Female tissues 523 | 18,647
Nervous System 521 | 18,561
Blood and immune system 520 | 17,995
Digestive Tract 519 | 18,473
Endocrine System 517 | 18,512
Cardiovascular System 516 | 17,958
Urinary Tract 516 | 18,444
Liver and Pancreas 515 | 18,136
Male tissues 514 | 17,969
Skin and soft tissues 513 | 18,115
Respiratory system 511 | 17,484

Target Family

Non-IDG 321 | 11,971
Enzyme 94 | 4,146
Kinase 75 | 634
Transcription Factor 19 | 1,400
Epigenetic 8 | 242
GPCR 4 | 406
Ion Channel 3 | 341
Transporter 3 | 473
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

UniProt Keyword

Apoptosis 529 | 529
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
ADP/ATP translocase 3 SLC25A6 Tbio Transporter -2.06581 118.3 193
Programmed cell death protein 4 PDCD4 Tchem Non-IDG -2.40380 284.9 546
Ubiquitin carboxyl-terminal hydrolase 17-like protein 1 USP17L1 Tdark Enzyme 10.9 3
Protein BEX3 BEX3 Tbio Non-IDG -1.87293 81.4 184
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 AIMP1 Tbio Enzyme -2.04569 136.6 321
TNF receptor-associated factor 2 TRAF2 Tbio Non-IDG -1.85843 68.9 516
Apoptosis inhibitor 5 API5 Tbio Non-IDG -1.32754 23.5 171
Acidic mammalian chitinase CHIA Tchem Enzyme -2.59382 419.7 126
CD5 antigen-like CD5L Tbio Non-IDG -1.78447 64.4 287