Development Level

Tbio 10 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

abnormal duodenum morphology 1 | 4
enlarged heart 1 | 210
enlarged spleen 1 | 41
preweaning lethality, incomple... 1 | 499

Disease

Aortic aneurysm 14 | 38
Aortic Valve Insufficiency 13 | 40
Hypertensive disease 13 | 292
Abnormality of the iris 12 | 14
Aortic aneurysm, familial thoracic 3 12 | 13
Ascending aortic dissection 12 | 13
Cardiomegaly 12 | 116
Chest Pain 12 | 38
Coronary artery disease 12 | 268
Cutis marmorata 12 | 32
Cystic medial necrosis of aorta 12 | 13
Descending aortic dissection 12 | 13
Dyspnea on exertion 12 | 24
Dyspnea, Paroxysmal 12 | 13
Familial thoracic aortic aneurysm and aortic dissection 12 | 13
Impaired left ventricular function 12 | 16
Increase in blood pressure 12 | 119
Left-Sided Heart Failure 12 | 16
Loeys-Dietz Aortic Aneurysm Syndrome 12 | 13
glioblastoma 12 | 5,792
ovarian cancer 12 | 8,520
Breast cancer 11 | 3,578
Carcinoma 11 | 11,493
Thoracic aortic aneurysm 10 | 15
ependymoma 10 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
malignant mesothelioma 10 | 3,232
atypical teratoid / rhabdoid tumor 9 | 5,112
lung cancer 9 | 4,740
osteosarcoma 9 | 7,950
pancreatic cancer 9 | 2,398
psoriasis 9 | 6,694
Astrocytoma, Pilocytic 8 | 3,081
adult high grade glioma 8 | 3,801
lung carcinoma 8 | 2,843
Dissection of aorta 7 | 9
Duchenne muscular dystrophy 7 | 601
Kidney cancer 7 | 2,613
Loeys-Dietz syndrome 7 | 23
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
Acquired scoliosis 6 | 281
Aortic Aneurysm, Thoracic 6 | 8
Cancer 6 | 2,499
Curvature of spine 6 | 282
Liver Cirrhosis 6 | 181
Liver Cirrhosis, Experimental 6 | 769
breast carcinoma 6 | 1,638
colon cancer 6 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
medulloblastoma, large-cell 6 | 6,241
Acquired flat foot 5 | 72
Arachnodactyly 5 | 49
Byzanthine arch palate 5 | 194
Flatfoot 5 | 73
Glaucoma 5 | 239
Linear atrophy 5 | 15
Orbital separation excessive 5 | 244
Patent ductus arteriosus 5 | 90
cystic fibrosis 5 | 1,696
ductal carcinoma in situ 5 | 1,745
group 3 medulloblastoma 5 | 4,104
juvenile dermatomyositis 5 | 1,187
limb girdle muscular dystrophy 2A 5 | 213
non-small cell lung cancer 5 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primitive neuroectodermal tumor 5 | 3,035
ulcerative colitis 5 | 1,819
Aneurysm, Dissecting 4 | 8
Arterial tortuosity 4 | 5
Atopic dermatitis 4 | 952
Ehlers-Danlos syndrome 4 | 43
Endometriosis 4 | 540
Hernia, Inguinal 4 | 89
Hypoplastic mandible condyle 4 | 275
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Mitral Valve Prolapse Syndrome 4 | 39
Pulmonary hypertension 4 | 85
Sternal anomalies 4 | 19
Tall stature 4 | 34
Ureteral obstruction 4 | 33
adrenocortical carcinoma 4 | 1,428
interstitial cystitis 4 | 2,312
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,109
pterygium 4 | 76
urothelial carcinoma 4 | 318
Becker muscular dystrophy 3 | 191
Pectus excavatum 3 | 100
Polycystic ovary syndrome 3 | 360
Retrognathia 3 | 54
Skin cancer 3 | 469
acute quadriplegic myopathy 3 | 1,158
diabetes mellitus 3 | 1,728
gastric carcinoma 3 | 807
nasopharyngeal carcinoma 3 | 1,058
nephrosclerosis 3 | 333
tuberculosis 3 | 2,010

Tissue

Endocrine System 14 | 18,159
Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Non-IDG 7 | 12,091
Kinase 4 | 634
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145

UniProt Keyword

Aortic aneurysm 14 | 14
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein E3 FOXE3 Tbio Transcription Factor -1.53701 31.5 150
Fibrillin-1 FBN1 Tbio Non-IDG -3.08679 1236.3 325
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384
Myosin-11 MYH11 Tbio Non-IDG -2.63453 415.3 263
Myosin light chain kinase, smooth muscle MYLK Tchem Kinase -2.81312 694.0 219
TGF-beta receptor type-2 TGFBR2 Tchem Kinase -2.84120 665.1 548
Collagen alpha-1(III) chain COL3A1 Tbio Non-IDG -2.58251 354.8 439
cGMP-dependent protein kinase 1 PRKG1 Tchem Kinase -2.70325 459.4 238
Mothers against decapentaplegic homolog 3 SMAD3 Tbio Transcription Factor -3.19667 1403.6 1526
Actin, aortic smooth muscle ACTA2 Tbio Non-IDG -2.25358 161.4 773