Development Level

Tbio 106 | 11,445
Tchem 7 | 1,598
Tdark 4 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased bone mineral content 5 | 151
decreased mean corpuscular vol... 4 | 79
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
abnormal behavior 3 | 298
abnormal bone structure 3 | 187
increased neutrophil cell numb... 3 | 46
abnormal embryo size 2 | 220
abnormal gait 2 | 69
decreased bone mineral density 2 | 126
decreased lymphocyte cell numb... 2 | 83
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
increased lean body mass 2 | 172
increased red blood cell distr... 2 | 34
abnormal esophagus morphology 1 | 5
abnormal hair growth 1 | 10
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal tooth morphology 1 | 24
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased lean body mass 1 | 135
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
enlarged gallbladder 1 | 2
enlarged kidney 1 | 14
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating total pr... 1 | 28
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
prolonged QRS complex duration 1 | 8
short tibia 1 | 97
tremors 1 | 39

Disease

Carcinoma 70 | 11,493
ovarian cancer 61 | 8,520
psoriasis 55 | 6,694
glioblastoma 49 | 5,792
osteosarcoma 47 | 7,950
juvenile dermatomyositis 45 | 1,187
lung cancer 45 | 4,740
medulloblastoma, large-cell 42 | 6,241
cutaneous lupus erythematosus 38 | 1,057
ependymoma 36 | 4,679
Astrocytoma, Pilocytic 34 | 3,081
Multiple Sclerosis 33 | 540
cystic fibrosis 33 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,291
Influenza 32 | 142
lung carcinoma 32 | 2,843
adult high grade glioma 30 | 3,801
dermatomyositis 30 | 966
malignant mesothelioma 28 | 3,232
pancreatic cancer 28 | 2,398
Breast cancer 27 | 3,578
Cancer 27 | 2,499
active Crohn's disease 27 | 922
subependymal giant cell astrocytoma 27 | 2,287
atypical teratoid / rhabdoid tumor 26 | 5,112
Microphthalmia with limb anomalies 25 | 40
primary Sjogren syndrome 25 | 735
Influenza, Human 24 | 51
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
tuberculosis 24 | 2,010
Systemic lupus erythematosus 23 | 194
group 4 medulloblastoma 21 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
invasive ductal carcinoma 21 | 2,951
interstitial cystitis 19 | 2,312
astrocytoma 18 | 1,146
ulcerative colitis 18 | 1,819
Multiple myeloma 16 | 1,332
active ulcerative colitis 16 | 764
Atopic dermatitis 15 | 952
Kidney cancer 15 | 2,613
Rheumatoid arthritis 15 | 1,191
group 3 medulloblastoma 15 | 4,104
pituitary cancer 15 | 1,972
Hepatitis C 14 | 94
breast carcinoma 14 | 1,638
acute quadriplegic myopathy 13 | 1,158
lung adenocarcinoma 13 | 2,716
Hepatitis 12 | 67
esophageal adenocarcinoma 12 | 737
nasopharyngeal carcinoma 12 | 1,058
diabetes mellitus 11 | 1,728
non-small cell lung cancer 11 | 2,890
oligodendroglioma 11 | 2,850
Autosomal recessive predisposition 10 | 1,442
Melanoma 10 | 711
pediatric high grade glioma 10 | 1,064
primary pancreatic ductal adenocarcinoma 10 | 1,109
primitive neuroectodermal tumor 10 | 3,035
Hepatitis B 9 | 108
Pick disease 9 | 1,894
hepatocellular carcinoma 9 | 547
Duchenne muscular dystrophy 8 | 601
Encephalitis 8 | 64
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Asthma 7 | 385
Liver Cirrhosis, Experimental 7 | 769
acute myeloid leukemia 7 | 783
astrocytic glioma 7 | 2,597
Aicardi-Goutieres syndrome 6 | 19
Breast Neoplasms 6 | 445
Down syndrome 6 | 499
Human immunodeficiency virus infectious disease 6 | 138
Liver Cirrhosis 6 | 181
Schizophrenia 6 | 1,160
colon cancer 6 | 1,478
progressive supranuclear palsy 6 | 676
sarcoidosis 6 | 370
Acquired immunodeficiency syndrome 5 | 197
Anemia 5 | 365
Arthritis, Rheumatoid 5 | 174
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Hypersensitivity reaction type II disease 5 | 253
Major Depressive Disorder 5 | 301
Mammary Neoplasms 5 | 425
Mental and motor retardation 5 | 608
Muscle Spasticity 5 | 195
Prostatic Neoplasms 5 | 495
Unipolar Depression 5 | 250
West Nile encephalitis 5 | 9
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
non primary Sjogren syndrome sicca 5 | 891
posterior fossa group A ependymoma 5 | 468
spina bifida 5 | 1,074
tuberculosis and treatment for 6 months 5 | 409
Arthritis 4 | 290
Bipolar Disorder 4 | 666
adrenocortical carcinoma 4 | 1,428
chronic lymphosyte leukemia 4 | 204

Tissue

Blood and immune system 104 | 16,909
Endocrine System 103 | 18,159
Male tissues 101 | 17,142
Skin and soft tissues 101 | 17,230
Digestive Tract 100 | 17,369
Urinary Tract 100 | 16,678
Female tissues 99 | 17,400
Liver and Pancreas 99 | 16,750
Respiratory system 99 | 16,393
Nervous System 98 | 16,725
Cardiovascular System 97 | 15,192

Target Family

Non-IDG 70 | 12,091
Enzyme 33 | 4,145
Transcription Factor 8 | 1,400
Kinase 5 | 634
Epigenetic 1 | 242
Transporter 1 | 473

UniProt Keyword

Antiviral defense 118 | 118
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
2'-5'-oligoadenylate synthase 3 OAS3 Tbio Enzyme -1.30083 17.8 141
DNA damage-inducible transcript 4 protein DDIT4 Tbio Non-IDG -2.11497 150.3 231
E3 ISG15--protein ligase HERC5 HERC5 Tbio Enzyme -1.63055 44.5 57
ATP-binding cassette sub-family F member 3 ABCF3 Tdark Transporter -0.30626 2.60 137
DNA-directed RNA polymerase III subunit RPC2 POLR3B Tbio Enzyme -1.25377 19.0 105
Zinc finger protein 175 ZNF175 Tbio Transcription Factor -0.86533 8.35 88
Serine incorporator 5 SERINC5 Tbio Non-IDG -1.50535 34.0 11
DNA dC->dU-editing enzyme APOBEC-3G APOBEC3G Tbio Non-IDG -2.78510 662.2 477
Interferon regulatory factor 5 IRF5 Tbio Transcription Factor -2.33923 241.0 400
Double-stranded RNA-specific editase 1 ADARB1 Tbio Enzyme -2.08959 118.0 103