Development Level

Tbio 27 | 11,445
Tchem 10 | 1,598
Tdark 6 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal sleep behavior 2 | 70
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased prepulse inhibition 2 | 82
abnormal behavior 1 | 298
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal gait 1 | 69
abnormal iris transilluminatio... 1 | 2
abnormal retina morphology 1 | 71
decreased circulating glucose ... 1 | 126
decreased fasted circulating g... 1 | 65
decreased startle reflex 1 | 75
enlarged thymus 1 | 5
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
small spleen 1 | 19

Disease

Carcinoma 34 | 11,493
osteosarcoma 19 | 7,950
glioblastoma 18 | 5,792
medulloblastoma, large-cell 18 | 6,241
atypical teratoid / rhabdoid tumor 16 | 5,112
adult high grade glioma 14 | 3,801
ependymoma 14 | 4,679
Kidney cancer 11 | 2,613
group 3 medulloblastoma 11 | 4,104
ovarian cancer 11 | 8,520
psoriasis 11 | 6,694
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
lung cancer 9 | 4,740
malignant mesothelioma 9 | 3,232
primitive neuroectodermal tumor 9 | 3,035
Astrocytoma, Pilocytic 8 | 3,081
Metabolic acidosis 8 | 90
Nephrolithiasis 8 | 56
astrocytic glioma 8 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
cystic fibrosis 7 | 1,696
pituitary cancer 7 | 1,972
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
subependymal giant cell astrocytoma 6 | 2,287
Autosomal recessive predisposition 5 | 1,442
Breast cancer 5 | 3,578
Diarrhea 5 | 253
Intellectual disability 5 | 1,016
Osteopetrosis 5 | 43
active ulcerative colitis 5 | 764
ductal carcinoma in situ 5 | 1,745
group 4 medulloblastoma 5 | 1,855
non primary Sjogren syndrome sicca 5 | 891
pancreatic cancer 5 | 2,398
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Brain Ischemia 4 | 110
Dent disease 4 | 18
Epilepsy 4 | 792
Melanoma 4 | 711
Pick disease 4 | 1,894
Short stature 4 | 531
Skin cancer 4 | 469
active Crohn's disease 4 | 922
aldosterone-producing adenoma 4 | 665
colon cancer 4 | 1,478
lung adenocarcinoma 4 | 2,716
Celiac disease 3 | 116
Diastrophic dysplasia 3 | 21
Edema 3 | 81
Hypertension 3 | 396
Nystagmus 3 | 317
Osteoporosis 3 | 363
Pendred Syndrome 3 | 22
Schnyder Corneal Dystrophy 3 | 23
Seizures 3 | 596
acute myeloid leukemia 3 | 783
adrenocortical carcinoma 3 | 1,428
interstitial cystitis 3 | 2,312
invasive ductal carcinoma 3 | 2,951
pancreatic carcinoma 3 | 562
pediatric high grade glioma 3 | 1,064
Autistic Disorder 2 | 364
Dementia 2 | 175
Failure to gain weight 2 | 365
Focal glomerulosclerosis 2 | 37
Frontal bossing 2 | 157
Gait Ataxia 2 | 51
Gastroesophageal reflux disease 2 | 110
Glycogen storage disease 2 | 39
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Heart disease 2 | 306
Heartburn 2 | 78
Hepatomegaly 2 | 285
Kidney Failure 2 | 111
Kidney disease 2 | 430
Liver cancer 2 | 604
Liver carcinoma 2 | 240
Microcephaly 2 | 166
Nephrocalcinosis 2 | 35
Ocular albinism 2 | 26
Ophthalmoplegia 2 | 106
Pediatric failure to thrive 2 | 365
Poor growth 2 | 114
Proteinuria 2 | 144
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
Severe mental retardation (I.Q. 20-34) 2 | 99
Status Epilepticus 2 | 98
Strabismus 2 | 270
acute quadriplegic myopathy 2 | 1,158
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group A ependymoma 2 | 468

Tissue

Endocrine System 42 | 18,159
Female tissues 41 | 17,400
Liver and Pancreas 41 | 16,750
Urinary Tract 41 | 16,678
Male tissues 40 | 17,142
Skin and soft tissues 40 | 17,230
Blood and immune system 39 | 16,909
Digestive Tract 39 | 17,369
Respiratory system 39 | 16,393
Nervous System 38 | 16,725
Cardiovascular System 35 | 15,192

Target Family

Transporter 34 | 473
Ion Channel 7 | 344
Non-IDG 2 | 12,091

UniProt Keyword

Antiport 43 | 43
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Anion exchange protein 4 SLC4A9 Tbio Transporter -1.76538 50.3 91
Sodium/potassium/calcium exchanger 3 SLC24A3 Tbio Transporter -1.12274 13.0 86
Sodium/potassium/calcium exchanger 2 SLC24A2 Tbio Transporter -1.39605 25.7 32
Sodium/hydrogen exchanger 9B2 SLC9B2 Tbio Transporter -1.21956 18.8 126
Sodium-coupled neutral amino acid transporter 3 SLC38A3 Tbio Transporter 0.00000 59
Anion exchange protein 2 SLC4A2 Tbio Transporter -1.53800 24.1 77
H(+)/Cl(-) exchange transporter 4 CLCN4 Tchem Ion Channel -1.51383 32.8 132
H(+)/Cl(-) exchange transporter 3 CLCN3 Tchem Ion Channel -2.27689 203.4 183
Chloride transport protein 6 CLCN6 Tchem Ion Channel -1.29202 19.5 74
Sodium/hydrogen exchanger 9 SLC9A9 Tbio Transporter -1.30329 22.7 147