Development Level

Tchem 18 | 1,890
Tbio 4 | 10,625
Tdark 4 | 7,003
Tclin 1 | 602

IMPC Term

decreased circulating calcium ... 2 | 33
decreased circulating phosphat... 2 | 15
decreased circulating triglyce... 2 | 83
increased circulating alkaline... 2 | 119
abnormal body size 1 | 1
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal cranium morphology 1 | 32
abnormal femur morphology 1 | 14
abnormal joint morphology 1 | 14
abnormal radius morphology 1 | 8
abnormal tail morphology 1 | 17
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
abnormal vertebral arch morpho... 1 | 9
decreased CD4-positive, alpha ... 1 | 19
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased alpha-beta T cell nu... 1 | 12
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased heart weight 1 | 44
increased circulating creatini... 1 | 29
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased effector memory CD4-... 1 | 15
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
short tail 1 | 4
thick tail 1 | 1

Disease

ovarian cancer 17 | 8,492
osteosarcoma 14 | 7,933
glioblastoma 9 | 5,572
atypical teratoid / rhabdoid tumor 8 | 4,369
lung cancer 8 | 4,473
psoriasis 8 | 6,685
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
medulloblastoma, large-cell 7 | 6,234
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
invasive ductal carcinoma 6 | 2,950
lung carcinoma 6 | 2,844
malignant mesothelioma 6 | 3,163
Breast cancer 5 | 3,099
Carcinoma 5 | 2,147
adult high grade glioma 5 | 2,148
cystic fibrosis 5 | 1,670
ductal carcinoma in situ 5 | 1,745
group 3 medulloblastoma 5 | 2,254
oligodendroglioma 5 | 2,849
pediatric high grade glioma 5 | 2,712
Hypertension 4 | 293
Multiple myeloma 4 | 1,328
Pick disease 4 | 1,893
diabetes mellitus 4 | 1,663
interstitial cystitis 4 | 2,299
pilocytic astrocytoma 4 | 3,086
primitive neuroectodermal tumor 4 | 3,031
sonic hedgehog group medulloblastoma 4 | 1,482
tuberculosis 4 | 1,563
ulcerative colitis 4 | 2,087
Cancer 3 | 2,346
Common variable immunodeficiency 3 | 98
Diabetes mellitus type 2 3 | 69
active Crohn's disease 3 | 918
acute quadriplegic myopathy 3 | 1,157
astrocytic glioma 3 | 2,241
breast carcinoma 3 | 1,614
esophageal adenocarcinoma 3 | 737
juvenile dermatomyositis 3 | 1,189
lung adenocarcinoma 3 | 2,714
nephrosclerosis 3 | 329
non-small cell lung cancer 3 | 2,798
pancreatic cancer 3 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
posterior fossa group A ependymoma 3 | 1,511
primary pancreatic ductal adenocarcinoma 3 | 1,271
spina bifida 3 | 1,064
Ankylosing spondylitis 2 | 138
Barrett's esophagus 2 | 185
Mammary Neoplasms, Experimental 2 | 150
Metabolic syndrome X 2 | 155
Polycystic Ovary Syndrome 2 | 335
Rheumatoid Arthritis 2 | 1,171
acute myeloid leukemia 2 | 785
cutaneous lupus erythematosus 2 | 1,056
dermatomyositis 2 | 967
ependymoma 2 | 2,514
group 4 medulloblastoma 2 | 1,875
interstitial lung disease 2 | 292
medulloblastoma 2 | 1,524
non primary Sjogren syndrome sicca 2 | 840
non-small cell lung carcinoma 2 | 413
posterior fossa group B ependymoma 2 | 1,530
primary Sjogren syndrome 2 | 789
tuberculosis and treatment for 6 months 2 | 686
Acquired metabolic disease 1 | 267
Amyotrophic Lateral Sclerosis 1 | 432
Anemia 1 | 252
Antiphospholipid syndrome 1 | 18
Bipolar Disorder 1 | 266
Bladder Neoplasm 1 | 109
Cataract 1 | 104
Chondrodysplasia punctata 1 | 41
Craniofacial Abnormalities 1 | 147
Glaucoma 1 | 135
Heart conduction disease 1 | 65
Hemolytic anemia 1 | 70
Hyperparathyroidism 1 | 43
Hyperphosphatemia 1 | 32
Hypoglycemia 1 | 81
Hypophosphatemia 1 | 31
Hypothyroidism 1 | 89
Infantile refsum disease 1 | 23
Inflammatory dermatosis 1 | 38
Necrosis 1 | 51
Nephrocalcinosis 1 | 18
Osteomalacia 1 | 28
Osteoporosis 1 | 259
Proteinuria 1 | 63
Rickets 1 | 42
Thrombocytopenia 1 | 105
Zellweger Syndrome 1 | 38
active ulcerative colitis 1 | 477
atypical teratoid/rhabdoid tumor 1 | 1,095
glioblastoma multiforme 1 | 347
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
permanent atrial fibrillation 1 | 44
sarcoidosis 1 | 368
tuberculosis and treatment for 3 months 1 | 327

Tissue

Blood and immune system 26 | 17,995
Cardiovascular System 26 | 17,958
Digestive Tract 26 | 18,473
Endocrine System 26 | 18,512
Female tissues 26 | 18,647
Liver and Pancreas 26 | 18,136
Male tissues 26 | 17,969
Nervous System 26 | 18,561
Respiratory system 26 | 17,484
Skin and soft tissues 26 | 18,115
Urinary Tract 26 | 18,444

Target Family

Enzyme 27 | 4,146

UniProt Keyword

Aminopeptidase 27 | 27
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aminopeptidase N ANPEP Tchem Enzyme -3.26833 1759.9 972
Dipeptidyl peptidase 2 DPP7 Tchem Enzyme -2.21518 163.3 173
Aspartyl aminopeptidase DNPEP Tchem Enzyme -1.49915 32.0 103
Dipeptidyl peptidase 3 DPP3 Tchem Enzyme -1.96977 95.9 188
Thyrotropin-releasing hormone-degrading ectoenzyme TRHDE Tdark Enzyme -1.61185 36.9 43
Methionine aminopeptidase 1 METAP1 Tchem Enzyme -1.63582 25.7 128
Puromycin-sensitive aminopeptidase-like protein NPEPPSL1 Tdark Enzyme 0.00000 0
Leucyl-cystinyl aminopeptidase LNPEP Tchem Enzyme -2.57078 390.0 98
Endoplasmic reticulum aminopeptidase 2 ERAP2 Tchem Enzyme -1.68056 46.0 70
Phosphate-regulating neutral endopeptidase PHEX Tbio Enzyme -3.23669 1694.4 98