Development Level

Tchem 14 | 1,388
Tbio 10 | 11,651
Tdark 2 | 6,593
Tclin 1 | 612

IMPC Phenotype

decreased circulating phosphat... 2 | 27
decreased circulating triglyce... 2 | 79
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal femur morphology 1 | 14
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal radius morphology 1 | 8
abnormal tail morphology 1 | 25
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
decreased IgE level 1 | 6
decreased IgG1 level 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased threshold for audito... 1 | 26
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased cardiac muscle contr... 1 | 8
increased circulating alkaline... 1 | 122
increased circulating creatini... 1 | 38
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased heart weight 1 | 62
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
long tail 1 | 1
mammalian phenotype 1 | 17
preweaning lethality, complete... 1 | 979
thick tail 1 | 1

Disease

Carcinoma 22 | 11,493
ovarian cancer 17 | 8,520
osteosarcoma 14 | 7,950
glioblastoma 10 | 5,792
atypical teratoid / rhabdoid tumor 9 | 5,112
lung cancer 9 | 4,740
adult high grade glioma 8 | 3,801
psoriasis 8 | 6,694
Kidney cancer 7 | 2,613
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
medulloblastoma, large-cell 7 | 6,241
cystic fibrosis 6 | 1,696
ependymoma 6 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
invasive ductal carcinoma 6 | 2,951
lung carcinoma 6 | 2,843
malignant mesothelioma 6 | 3,232
Breast cancer 5 | 3,578
ductal carcinoma in situ 5 | 1,745
oligodendroglioma 5 | 2,850
Astrocytoma, Pilocytic 4 | 3,081
Hypertension 4 | 396
Liver Cirrhosis, Experimental 4 | 769
Multiple myeloma 4 | 1,332
Pick disease 4 | 1,894
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
non-small cell lung cancer 4 | 2,890
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
Common variable immunodeficiency 3 | 101
Diabetes mellitus type 2 3 | 69
active Crohn's disease 3 | 922
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
esophageal adenocarcinoma 3 | 737
group 4 medulloblastoma 3 | 1,855
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
nephrosclerosis 3 | 333
non primary Sjogren syndrome sicca 3 | 891
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Ankylosing spondylitis 2 | 140
Arthralgia 2 | 90
Barrett's esophagus 2 | 182
Behcet's disease 2 | 89
Cancer 2 | 2,499
Crohn's disease 2 | 321
Hemiparesis 2 | 34
Major Depressive Disorder 2 | 301
Mammary Neoplasms, Experimental 2 | 154
Polycystic ovary syndrome 2 | 360
Rheumatoid arthritis 2 | 1,191
Unipolar Depression 2 | 250
active ulcerative colitis 2 | 764
acute myeloid leukemia 2 | 783
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
interstitial lung disease 2 | 298
pediatric high grade glioma 2 | 1,064
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis and treatment for 6 months 2 | 409
Acne 1 | 52
Alkaline phosphatase serum increased 1 | 29
Amyloidosis 1 | 67
Angioedema 1 | 38
Anovulation 1 | 21
Atrophic rhinitis 1 | 8
Calcinosis 1 | 70
Celiac disease 1 | 116
Ciliopathy 1 | 71
Confusion 1 | 21
Defective tooth enamel 1 | 31
Dystrophic tooth enamel 1 | 31
Enamel abnormalities 1 | 31
Exocrine pancreatic insufficiency 1 | 32
Goodpasture syndrome 1 | 6
Hodgkin's lymphoma 1 | 15
Hyperglycemia 1 | 137
Iris disease 1 | 10
Nasopharyngitis 1 | 11
Ovarian Failure, Premature 1 | 9
Pancreatitis 1 | 123
Precancerous Conditions 1 | 80
Premature ovarian failure 1 | 65
Pulmonary Fibrosis 1 | 106
Recurrent otitis media 1 | 42
Right bundle branch block 1 | 17
Sickle Cell Anemia 1 | 53
Specific language impairment 1 | 34
Spondylitis, Ankylosing 1 | 11
Tetanus 1 | 68
Tonsillitis 1 | 16

Tissue

Blood and immune system 26 | 16,909
Digestive Tract 26 | 17,369
Endocrine System 26 | 18,159
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678
Cardiovascular System 25 | 15,192

Target Family

Enzyme 27 | 4,145

UniProt Keyword

Aminopeptidase 27 | 27
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tripeptidyl-peptidase 2 TPP2 Tbio Enzyme -1.97332 108.2 72
Aspartyl aminopeptidase DNPEP Tchem Enzyme -1.52163 32.9 138
Thyrotropin-releasing hormone-degrading ectoenzyme TRHDE Tbio Enzyme -1.62910 39.1 51
Leucyl-cystinyl aminopeptidase LNPEP Tchem Enzyme -2.57244 394.0 103
Endoplasmic reticulum aminopeptidase 1 ERAP1 Tchem Enzyme -2.32434 221.0 216
Glutamyl aminopeptidase ENPEP Tchem Enzyme -2.81719 655.7 311
Methionine aminopeptidase 2 METAP2 Tchem Enzyme -0.86233 8.18 191
Phosphate-regulating neutral endopeptidase PHEX Tbio Enzyme -3.26526 1840.1 104
Methionine aminopeptidase 1D, mitochondrial METAP1D Tbio Enzyme -0.48565 3.02 99
Dipeptidyl peptidase 8 DPP8 Tchem Enzyme -1.95275 78.0 195