Development Level

Tbio 26 | 11,445
Tchem 13 | 1,598
Tdark 7 | 6,588

IMPC Phenotype

abnormal epididymis morphology 2 | 42
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased total body fat amoun... 2 | 207
enlarged epididymis 2 | 31
increased circulating iron lev... 2 | 30
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal maxilla morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal response to tactile s... 1 | 17
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal urinary bladder morph... 1 | 11
abnormal vitreous body morphol... 1 | 10
cystolithiasis 1 | 3
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating glucose ... 1 | 24
increased circulating glycerol... 1 | 9
increased circulating phosphat... 1 | 26
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
polycystic kidney 1 | 15
short tibia 1 | 97
small kidney 1 | 16

Disease

Carcinoma 35 | 11,493
osteosarcoma 20 | 7,950
ependymoma 17 | 4,679
medulloblastoma, large-cell 17 | 6,241
atypical teratoid / rhabdoid tumor 16 | 5,112
glioblastoma 16 | 5,792
ovarian cancer 16 | 8,520
psoriasis 15 | 6,694
lung cancer 14 | 4,740
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
malignant mesothelioma 11 | 3,232
Astrocytoma, Pilocytic 10 | 3,081
Cystinuria 10 | 18
Lysinuric protein intolerance 10 | 15
group 3 medulloblastoma 10 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
lung carcinoma 10 | 2,843
oligodendroglioma 10 | 2,850
subependymal giant cell astrocytoma 10 | 2,287
Breast cancer 9 | 3,578
adult high grade glioma 9 | 3,801
primitive neuroectodermal tumor 9 | 3,035
tuberculosis 9 | 2,010
Schizophrenia 8 | 1,160
non-small cell lung cancer 8 | 2,890
pancreatic cancer 8 | 2,398
pituitary cancer 8 | 1,972
Cancer 7 | 2,499
Pick disease 7 | 1,894
cystic fibrosis 7 | 1,696
interstitial cystitis 7 | 2,312
invasive ductal carcinoma 7 | 2,951
pediatric high grade glioma 7 | 1,064
Hartnup disease 6 | 13
active Crohn's disease 6 | 922
active ulcerative colitis 6 | 764
astrocytic glioma 6 | 2,597
colon cancer 6 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
ulcerative colitis 6 | 1,819
Autosomal recessive predisposition 5 | 1,442
Epilepsy 5 | 792
ductal carcinoma in situ 5 | 1,745
lung adenocarcinoma 5 | 2,716
Amyotrophic lateral sclerosis 4 | 451
Bipolar Disorder 4 | 666
Dicarboxylic aminoaciduria 4 | 4
Endometriosis 4 | 540
Iminoglycinuria 4 | 4
Kidney cancer 4 | 2,613
Rheumatoid arthritis 4 | 1,191
Seizures 4 | 596
atypical teratoid/rhabdoid tumor 4 | 357
breast carcinoma 4 | 1,638
group 4 medulloblastoma 4 | 1,855
Alcoholic Intoxication, Chronic 3 | 289
Atopic dermatitis 3 | 952
Barrett's esophagus 3 | 182
Failure to gain weight 3 | 365
HYPERGLYCINURIA (disorder) 3 | 12
Hyperglycinuria 3 | 3
Muscle hypotonia 3 | 571
Pediatric failure to thrive 3 | 365
Polycystic ovary syndrome 3 | 360
Toxic encephalopathy 3 | 141
astrocytoma 3 | 1,146
cutaneous lupus erythematosus 3 | 1,057
gastric carcinoma 3 | 807
nephrosclerosis 3 | 333
non primary Sjogren syndrome sicca 3 | 891
progressive supranuclear palsy 3 | 676
spina bifida 3 | 1,074
Congenital Epicanthus 2 | 177
Depressive disorder 2 | 409
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Hepatomegaly 2 | 285
Kidney Failure 2 | 111
Liver Cirrhosis, Experimental 2 | 769
Lung Neoplasms 2 | 232
Major Depressive Disorder 2 | 301
Mental Depression 2 | 333
Nephrolithiasis 2 | 56
Parkinson's disease 2 | 392
Pellagra 2 | 26
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
Unipolar Depression 2 | 250
Vascular disease 2 | 319
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
chronic rhinosinusitis 2 | 512
fibroadenoma 2 | 559
juvenile dermatomyositis 2 | 1,187
mucosa-associated lymphoid tissue lymphoma 2 | 484
non diabetic and post-ischemic heart failure 2 | 200
pancreatic carcinoma 2 | 562
posterior fossa group B ependymoma 2 | 416
sonic hedgehog group medulloblastoma 2 | 467

Tissue

Endocrine System 45 | 18,159
Male tissues 45 | 17,142
Digestive Tract 44 | 17,369
Nervous System 44 | 16,725
Skin and soft tissues 44 | 17,230
Urinary Tract 44 | 16,678
Blood and immune system 43 | 16,909
Female tissues 43 | 17,400
Liver and Pancreas 41 | 16,750
Respiratory system 39 | 16,393
Cardiovascular System 35 | 15,192

Target Family

Transporter 44 | 473
Non-IDG 2 | 12,091

UniProt Keyword

Amino-acid transport 46 | 46
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cationic amino acid transporter 3 SLC7A3 Tbio Transporter -2.20835 146.6 38
Large neutral amino acids transporter small subunit 1 SLC7A5 Tbio Transporter -1.90516 156.1 254
Sodium-dependent proline transporter SLC6A7 Tchem Transporter -2.10260 134.1 45
Proton-coupled amino acid transporter 2 SLC36A2 Tchem Transporter -1.78507 61.5 88
Sodium-coupled neutral amino acid transporter 3 SLC38A3 Tbio Transporter 0.00000 59
Putative sodium-coupled neutral amino acid transporter 10 SLC38A10 Tdark Transporter -0.27712 1.71 25
Cationic amino acid transporter 2 SLC7A2 Tbio Transporter -1.55868 37.6 57
Sodium-coupled neutral amino acid transporter 2 SLC38A2 Tbio Transporter -1.98482 96.5 91
Excitatory amino acid transporter 4 SLC1A6 Tchem Transporter -1.89314 75.8 107
Sodium-dependent neutral amino acid transporter B(0)AT1 SLC6A19 Tchem Transporter -1.89653 74.4 32