Development Level

Tbio 19 | 11,445
Tchem 2 | 1,598

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

abnormal kidney morphology 1 | 65
abnormal skin morphology 1 | 50
abnormal tooth morphology 1 | 24
decreased heart rate 1 | 18
decreased lymphocyte cell numb... 1 | 83
enlarged thymus 1 | 5
enlarged uterus 1 | 11
hydrometra 1 | 53
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased monocyte cell number 1 | 63
preweaning lethality, incomple... 1 | 499
prolonged ST segment 1 | 36
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Amelogenesis imperfecta 21 | 29
Carcinoma 13 | 11,493
Autosomal recessive predisposition 11 | 1,442
medulloblastoma, large-cell 11 | 6,241
ovarian cancer 10 | 8,520
Amelogenesis Imperfecta hypomaturation type 7 | 7
osteosarcoma 7 | 7,950
Dental Enamel Hypoplasia 6 | 43
invasive ductal carcinoma 6 | 2,951
pancreatic cancer 6 | 2,398
psoriasis 6 | 6,694
Defective enamel matrix 5 | 35
Dental caries 5 | 164
Dysplasia of tooth enamel 5 | 35
Thin dental enamel 5 | 35
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
non-small cell lung cancer 5 | 2,890
tuberculosis 5 | 2,010
Ameloblastoma 4 | 24
Dental fluorosis 4 | 20
Dentin dysplasia 4 | 19
Dentinogenesis imperfecta 4 | 25
Epilepsy 4 | 792
Short stature 4 | 531
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
interstitial cystitis 4 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Abnormality of metabolism/homeostasis 3 | 134
Abnormality of retinal pigmentation 3 | 111
Amelogenesis Imperfecta, Type III 3 | 3
Anteverted nostril 3 | 191
Astrocytoma, Pilocytic 3 | 3,081
Brachyolmia 3 | 5
Breast cancer 3 | 3,578
Death in early childhood 3 | 82
Death in infancy 3 | 82
Decreased size of teeth 3 | 62
Decreased width of tooth 3 | 59
Delayed bone age 3 | 136
Difficulties with night vision 3 | 87
Electroencephalogram abnormal 3 | 101
Failure to gain weight 3 | 365
Intellectual disability 3 | 1,016
Kidney cancer 3 | 2,613
Liver diseases 3 | 87
Long narrow head 3 | 75
Low Vision 3 | 174
Microdontia (disorder) 3 | 59
Muscle hypotonia 3 | 571
Narrow cranium shape 3 | 75
Narrow head shape 3 | 75
Narrow skull shape 3 | 75
Night Blindness 3 | 101
Nystagmus 3 | 317
Optic Atrophy 3 | 242
Pediatric failure to thrive 3 | 365
Pyloric Stenosis 3 | 47
Retinal pigment epithelial abnormality 3 | 111
Retinitis Pigmentosa 3 | 226
Rotting teeth 3 | 73
Seizures 3 | 596
Small head 3 | 374
Tooth agenesis 3 | 44
Turridolichocephaly 3 | 75
Visual Impairment 3 | 174
Yellow-brown discoloration of the teeth 3 | 3
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
group 3 medulloblastoma 3 | 4,104
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Addison Disease 2 | 18
Adrenal cortical hypofunction 2 | 23
Adrenoleukodystrophy, Neonatal 2 | 13
Embryotoxon 2 | 28
Flat occiput 2 | 26
Global developmental delay, severe 2 | 47
High forehead 2 | 102
Hydronephrosis 2 | 89
Icterus 2 | 82
Infantile Refsum Disease (disorder) 2 | 13
Infantile Refsum disease 2 | 23
Liver Failure 2 | 73
Malformations of Cortical Development, Group II 2 | 31
Malformed pinnae 2 | 37
Muscle weakness, progressive 2 | 22
Osteochondrodysplasias 2 | 72
Penile hypospadias 2 | 106
Peroxisome biogenesis disorders 2 | 11
Posterior embryotoxon 2 | 28
Sensorineural Hearing Loss (disorder) 2 | 284
Visual field constriction 2 | 36

Tissue

Endocrine System 21 | 18,159
Blood and immune system 20 | 16,909
Digestive Tract 19 | 17,369
Female tissues 19 | 17,400
Male tissues 18 | 17,142
Nervous System 17 | 16,725
Skin and soft tissues 17 | 17,230
Respiratory system 16 | 16,393
Urinary Tract 16 | 16,678
Liver and Pancreas 15 | 16,750
Cardiovascular System 14 | 15,192

Target Family

Non-IDG 12 | 12,091
Enzyme 6 | 4,145
GPCR 1 | 408
Transcription Factor 1 | 1,400
Transporter 1 | 473

UniProt Keyword

Amelogenesis imperfecta 21 | 21
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Metal transporter CNNM4 CNNM4 Tbio Non-IDG -1.18531 16.5 123
Peroxisome biogenesis factor 1 PEX1 Tbio Enzyme -0.77059 5.43 107
Peroxisome assembly factor 2 PEX6 Tbio Enzyme -1.89379 79.8 148
Protein FAM83H FAM83H Tbio Non-IDG -1.55201 35.7 25
Testicular acid phosphatase ACP4 Tbio Enzyme -1.57171 37.4 65
Sodium/potassium/calcium exchanger 4 SLC24A4 Tbio Transporter -1.32054 20.8 63
Homeobox protein DLX-3 DLX3 Tbio Transcription Factor -2.07559 128.5 176
WD repeat-containing protein 72 WDR72 Tbio Non-IDG -0.84192 8.37 10
Latent-transforming growth factor beta-binding protein 3 LTBP3 Tbio Non-IDG -3.14299 1230.0 4
Enamelin ENAM Tbio Non-IDG -2.25637 174.2 73