Development Level

Tbio 74 | 11,445
Tchem 27 | 1,598
Tclin 8 | 613
Tdark 6 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal heart morphology 3 | 162
decreased mean corpuscular vol... 3 | 79
abnormal behavior 2 | 298
abnormal retina morphology 2 | 71
abnormal testis morphology 2 | 43
decreased circulating serum al... 2 | 82
decreased vertical activity 2 | 208
enlarged heart 2 | 210
hypoactivity 2 | 132
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal iris pigmentation 1 | 4
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating fructosa... 1 | 30
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased pulmonary respirator... 1 | 5
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
enlarged testis 1 | 6
enlarged urinary bladder 1 | 8
hydrometra 1 | 53
hyperactivity 1 | 148
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased or absent threshold ... 1 | 101
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 66 | 11,493
ovarian cancer 56 | 8,520
Cancer 48 | 2,499
osteosarcoma 45 | 7,950
psoriasis 44 | 6,694
lung cancer 39 | 4,740
medulloblastoma, large-cell 39 | 6,241
glioblastoma 38 | 5,792
malignant mesothelioma 31 | 3,232
Breast cancer 29 | 3,578
atypical teratoid / rhabdoid tumor 28 | 5,112
lung adenocarcinoma 25 | 2,716
non-small cell lung cancer 25 | 2,890
group 3 medulloblastoma 24 | 4,104
lung carcinoma 24 | 2,843
ependymoma 23 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
pancreatic cancer 21 | 2,398
tuberculosis 21 | 2,010
Schizophrenia 20 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
diabetes mellitus 18 | 1,728
primitive neuroectodermal tumor 18 | 3,035
ulcerative colitis 18 | 1,819
breast carcinoma 17 | 1,638
interstitial cystitis 17 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
invasive ductal carcinoma 17 | 2,951
Multiple myeloma 16 | 1,332
Rheumatoid arthritis 16 | 1,191
adult high grade glioma 16 | 3,801
Astrocytoma, Pilocytic 15 | 3,081
Autosomal recessive predisposition 15 | 1,442
acute quadriplegic myopathy 14 | 1,158
cystic fibrosis 14 | 1,696
astrocytoma 13 | 1,146
ductal carcinoma in situ 13 | 1,745
group 4 medulloblastoma 13 | 1,855
primary pancreatic ductal adenocarcinoma 13 | 1,109
Breast Neoplasms 12 | 445
Kidney cancer 12 | 2,613
Mammary Neoplasms 12 | 425
astrocytic glioma 12 | 2,597
colon cancer 12 | 1,478
dermatomyositis 12 | 966
juvenile dermatomyositis 12 | 1,187
oligodendroglioma 12 | 2,850
subependymal giant cell astrocytoma 12 | 2,287
nasopharyngeal carcinoma 11 | 1,058
spina bifida 11 | 1,074
Depressive disorder 10 | 409
Neurodegenerative disease 10 | 414
Prostatic Neoplasms 10 | 495
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Bipolar Disorder 9 | 666
Hypertension 9 | 396
Hypertensive disease 9 | 292
Liver Cirrhosis, Experimental 9 | 769
Muscle hypotonia 9 | 571
Obesity 9 | 678
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
pituitary cancer 9 | 1,972
Cognitive delay 8 | 608
Crohn's disease 8 | 321
Global developmental delay 8 | 608
Lung Neoplasms 8 | 232
Mental and motor retardation 8 | 608
Vascular disease 8 | 319
active ulcerative colitis 8 | 764
acute myeloid leukemia 8 | 783
medulloblastoma 8 | 720
Alzheimer's disease 7 | 658
Dementia 7 | 175
Down syndrome 7 | 499
Duchenne muscular dystrophy 7 | 601
Pick disease 7 | 1,894
Short stature 7 | 531
Waldenstrons macroglobulinemia 7 | 765
adrenocortical carcinoma 7 | 1,428
esophageal adenocarcinoma 7 | 737
gastric carcinoma 7 | 807
non primary Sjogren syndrome sicca 7 | 891
pancreatic carcinoma 7 | 562
pediatric high grade glioma 7 | 1,064
Anemia 6 | 365
Dull intelligence 6 | 645
Endometrial cancer 6 | 311
Epilepsy 6 | 792
Heart disease 6 | 306
Intellectual disability 6 | 1,016
Kidney disease 6 | 430
Low intelligence 6 | 645
Mental Depression 6 | 333
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
Psychotic Disorders 6 | 151
Stomach Neoplasms 6 | 300
active Crohn's disease 6 | 922
fibroadenoma 6 | 559

Tissue

Endocrine System 107 | 18,159
Digestive Tract 106 | 17,369
Nervous System 106 | 16,725
Blood and immune system 105 | 16,909
Female tissues 105 | 17,400
Liver and Pancreas 105 | 16,750
Skin and soft tissues 105 | 17,230
Male tissues 104 | 17,142
Respiratory system 104 | 16,393
Urinary Tract 104 | 16,678
Cardiovascular System 101 | 15,192

Target Family

Non-IDG 55 | 12,091
Enzyme 34 | 4,145
Kinase 11 | 634
Transcription Factor 8 | 1,400
Ion Channel 2 | 344
Transporter 2 | 473
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

UniProt Keyword

Alternative initiation 115 | 115
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Beta-crystallin A3 CRYBA1 Tbio Non-IDG -1.45158 27.2 133
Insulin-like growth factor 2 mRNA-binding protein 2 IGF2BP2 Tbio Non-IDG -1.77792 57.3 400
Cysteine desulfurase, mitochondrial NFS1 Tbio Enzyme -1.70267 46.3 131
BAG family molecular chaperone regulator 1 BAG1 Tbio Non-IDG -2.50252 335.1 394
Zinc finger protein 385A ZNF385A Tbio Non-IDG -0.03141 1.24 99
Endonuclease III-like protein 1 NTHL1 Tbio Enzyme -1.85066 66.8 155
Carbohydrate sulfotransferase 2 CHST2 Tbio Enzyme -1.29443 20.9 188
Malonyl-CoA decarboxylase, mitochondrial MLYCD Tchem Enzyme -1.70434 46.1 67
Transcription factor NF-E4 NFE4 Tbio Non-IDG 0.00000 0