Development Level

Tchem 22 | 1,890
Tbio 20 | 10,625
Tclin 6 | 602

Collection

Eligible Kinase Proteins 3 | 134

IMPC Term

increased circulating chloride... 2 | 43
preweaning lethality, incomple... 2 | 260
abnormal bone structure 1 | 131
abnormal cranium morphology 1 | 32
abnormal hair texture 1 | 4
abnormal incisor morphology 1 | 3
abnormal lens morphology 1 | 73
abnormal lumbar vertebrae morp... 1 | 6
abnormal maxilla morphology 1 | 16
abnormal vibrissa morphology 1 | 17
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased fasted circulating g... 1 | 49
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
increased blood urea nitrogen ... 1 | 44
increased circulating amylase ... 1 | 13
increased circulating calcium ... 1 | 32
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased heart weight 1 | 37
increased mean corpuscular hem... 1 | 93
increased or absent threshold ... 1 | 128

Disease

ovarian cancer 31 | 8,492
psoriasis 27 | 6,685
medulloblastoma, large-cell 26 | 6,234
osteosarcoma 26 | 7,933
lung cancer 22 | 4,473
glioblastoma 20 | 5,572
malignant mesothelioma 18 | 3,163
non-small cell lung cancer 18 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,289
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,795
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,956
invasive ductal carcinoma 15 | 2,950
atypical teratoid / rhabdoid tumor 14 | 4,369
primitive neuroectodermal tumor 14 | 3,031
lung carcinoma 13 | 2,844
pediatric high grade glioma 13 | 2,712
pilocytic astrocytoma 13 | 3,086
Breast cancer 12 | 3,099
ependymoma 11 | 2,514
group 4 medulloblastoma 11 | 1,875
group 3 medulloblastoma 10 | 2,254
oligodendroglioma 10 | 2,849
Carcinoma 9 | 2,147
Obesity 9 | 616
adrenocortical carcinoma 9 | 1,427
diabetes mellitus 9 | 1,663
pancreatic cancer 9 | 2,300
subependymal giant cell astrocytoma 9 | 2,287
Cancer 8 | 2,346
breast carcinoma 8 | 1,614
ductal carcinoma in situ 8 | 1,745
lung adenocarcinoma 8 | 2,714
pituitary cancer 8 | 1,972
tuberculosis 8 | 1,563
ulcerative colitis 8 | 2,087
aldosterone-producing adenoma 7 | 664
astrocytic glioma 7 | 2,241
atypical teratoid/rhabdoid tumor 7 | 1,095
colon cancer 7 | 1,475
dermatomyositis 7 | 967
interstitial cystitis 7 | 2,299
Glycogen storage disease 6 | 37
Myocardial Ischemia 6 | 169
astrocytoma 6 | 1,493
medulloblastoma 6 | 1,524
posterior fossa group A ependymoma 6 | 1,511
primary Sjogren syndrome 6 | 789
sonic hedgehog group medulloblastoma 6 | 1,482
Atrial Fibrillation 5 | 110
Liver carcinoma 5 | 217
Pick disease 5 | 1,893
Schizophrenia 5 | 503
Waldenstrons macroglobulinemia 5 | 765
adult high grade glioma 5 | 2,148
cystic fibrosis 5 | 1,670
esophageal adenocarcinoma 5 | 737
posterior fossa group B ependymoma 5 | 1,530
Anemia 4 | 252
Bipolar Disorder 4 | 266
Diabetes Mellitus, Experimental 4 | 106
Hypertension 4 | 293
Myopathy 4 | 128
Neurodegenerative disease 4 | 383
Rheumatoid Arthritis 4 | 1,171
Type 2 diabetes mellitus 4 | 192
acute quadriplegic myopathy 4 | 1,157
cutaneous lupus erythematosus 4 | 1,056
juvenile dermatomyositis 4 | 1,189
Atherosclerosis 3 | 275
Atopic dermatitis 3 | 944
Biotin deficiency 3 | 9
Chronic heart failure 3 | 46
Coronary artery disease 3 | 240
Dementia 3 | 129
Diabetes Mellitus, Non-Insulin-Dependent 3 | 161
Down syndrome 3 | 548
Glycogen storage disease V 3 | 7
Heart disease 3 | 279
Impotence 3 | 45
Kidney disease 3 | 397
Liver Cirrhosis, Experimental 3 | 108
Liver diseases 3 | 66
Multiple myeloma 3 | 1,328
Myocardial Perfusion Imaging Adjunct 3 | 25
Neuropathy 3 | 210
Peripheral vascular disease 3 | 90
Platelet Aggregation Inhibition 3 | 22
Prevention of Cerebral Thrombosis 3 | 29
Pulmonary hypertension 3 | 52
Renal Cell Carcinoma 3 | 199
gastric carcinoma 3 | 832
glioblastoma multiforme 3 | 347
nephrosclerosis 3 | 329
primary pancreatic ductal adenocarcinoma 3 | 1,271
spina bifida 3 | 1,064
Alzheimer's disease 2 | 644
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
nasopharyngeal carcinoma 2 | 1,056
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 48 | 17,995
Cardiovascular System 48 | 17,958
Digestive Tract 48 | 18,473
Endocrine System 48 | 18,512
Female tissues 48 | 18,647
Liver and Pancreas 48 | 18,136
Male tissues 48 | 17,969
Nervous System 48 | 18,561
Respiratory system 48 | 17,484
Urinary Tract 48 | 18,444
Skin and soft tissues 47 | 18,115

Target Family

Enzyme 29 | 4,146
Kinase 16 | 634
Non-IDG 3 | 11,969

UniProt Keyword

Allosteric enzyme 48 | 48
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTP cyclohydrolase 1 GCH1 Tbio Enzyme -2.78255 613.4 202
Calcium/calmodulin-dependent protein kinase type 1G CAMK1G Tchem Kinase -0.58501 4.18 193
Hexokinase-2 HK2 Tchem Kinase -2.60415 391.1 373
CAD protein CAD Tchem Non-IDG -2.23424 164.6 201
Hexokinase-3 HK3 Tbio Kinase -1.70703 47.9 299
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.66762 4846.8 245
Glycogen [starch] synthase, liver GYS2 Tbio Enzyme -1.56596 34.7 62
ATP-dependent 6-phosphofructokinase, liver type PFKL Tbio Kinase -2.05790 104.4 212
Pyruvate kinase PKLR PKLR Tbio Kinase -2.35902 217.3 337
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 SAMHD1 Tbio Enzyme -3.94523 8199.4 204