Development Level

Tbio 80 | 10,625
Tdark 59 | 7,003
Tchem 23 | 1,890
Tclin 10 | 602

Collection

Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

decreased lean body mass 4 | 195
preweaning lethality, complete... 4 | 633
embryonic lethality prior to t... 3 | 187
decreased bone mineral content 2 | 157
abnormal eye posterior chamber... 1 | 3
abnormal heart position or ori... 1 | 1
abnormal seminal vesicle morph... 1 | 47
decreased body weight 1 | 174
decreased circulating alanine ... 1 | 53
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased heart rate 1 | 10
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
female infertility 1 | 34
increased CD4-positive, alpha ... 1 | 15
increased KLRG1+ CD8 alpha bet... 1 | 2
increased bone mineral content 1 | 92
increased circulating calcium ... 1 | 32
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased total body fat amoun... 1 | 57
prolonged RR interval 1 | 2

Disease

osteosarcoma 83 | 7,933
ovarian cancer 60 | 8,484
interstitial cystitis 58 | 2,299
lung cancer 56 | 4,466
psoriasis 56 | 6,685
lung carcinoma 49 | 2,844
ulcerative colitis 47 | 2,087
cutaneous lupus erythematosus 45 | 1,056
glioblastoma 42 | 5,572
primary Sjogren syndrome 41 | 789
Cancer 38 | 2,346
tuberculosis 35 | 1,557
medulloblastoma, large-cell 34 | 6,234
invasive ductal carcinoma 30 | 2,950
pilocytic astrocytoma 29 | 3,086
non-small cell lung cancer 28 | 2,798
subependymal giant cell astrocytoma 26 | 2,287
lung adenocarcinoma 24 | 2,713
Rheumatoid Arthritis 18 | 1,160
atypical teratoid / rhabdoid tumor 17 | 4,369
chronic lymphosyte leukemia 17 | 232
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
pediatric high grade glioma 17 | 2,712
Multiple myeloma 16 | 1,327
astrocytoma 16 | 1,493
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,289
pancreatic cancer 16 | 2,300
Breast cancer 15 | 3,094
adult high grade glioma 15 | 2,148
diabetes mellitus 15 | 1,663
oligodendroglioma 15 | 2,849
periodontitis 15 | 269
cystic fibrosis 14 | 1,665
head and neck cancer and chronic obstructive pulmonary disease 14 | 237
malignant mesothelioma 14 | 3,162
ductal carcinoma in situ 13 | 1,745
juvenile dermatomyositis 13 | 1,189
mucosa-associated lymphoid tissue lymphoma 13 | 480
active Crohn's disease 12 | 918
acute myeloid leukemia 12 | 780
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,956
primary pancreatic ductal adenocarcinoma 12 | 1,271
Crohn's disease 11 | 304
Lupus erythematosus 11 | 80
colon cancer 11 | 1,475
esophageal adenocarcinoma 11 | 737
sarcoidosis 11 | 358
Carcinoma 10 | 2,147
Multiple Sclerosis 10 | 498
Waldenstrons macroglobulinemia 10 | 765
group 4 medulloblastoma 10 | 1,875
nasopharyngeal carcinoma 10 | 1,056
IGA Glomerulonephritis 9 | 454
ependymoma 9 | 2,514
gastric cancer 9 | 430
group 3 medulloblastoma 9 | 2,254
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
posterior fossa group A ependymoma 9 | 1,511
primitive neuroectodermal tumor 9 | 3,031
breast carcinoma 8 | 1,614
cystic fibrosis and chronic rhinosinusitis 8 | 213
dermatomyositis 8 | 933
Agammaglobulinemia 7 | 24
Asthma 7 | 349
Atopic dermatitis 7 | 944
Celiac disease 7 | 112
Chronic Lymphocytic Leukemia 7 | 242
Dysgammaglobulinemia 7 | 9
astrocytic glioma 7 | 2,241
Allergic hypersensitivity disease 6 | 123
Blastic phase chronic myeloid leukemia 6 | 58
Chronic Myelocytic Leukemia Accelerated Phase 6 | 59
Human immunodeficiency virus infectious disease 6 | 92
Hypersensitivity reaction type II disease 6 | 235
Leprosy 6 | 77
Lung disease 6 | 132
Pick disease 6 | 1,893
Schizophrenia 6 | 501
Severe Combined Immunodeficiency 6 | 46
gastric carcinoma 6 | 832
non-small cell lung carcinoma 6 | 413
pancreatic carcinoma 6 | 567
pituitary cancer 6 | 1,972
tuberculosis and treatment for 3 months 6 | 327
tuberculosis and treatment for 6 months 6 | 686
Adult T-Cell Lymphoma/Leukemia 5 | 30
Anemia 5 | 252
Arthritis 5 | 248
Hepatitis B 5 | 103
Infectious mononucleosis 5 | 15
Liver disease 5 | 219
Melanoma 5 | 261
Peripheral Neuropathy 5 | 303
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 5 | 45
Prostatic Neoplasms 5 | 471
adrenocortical carcinoma 5 | 1,427
atypical teratoid/rhabdoid tumor 5 | 1,095
chronic rhinosinusitis 5 | 512
inflammatory breast cancer 5 | 404
medulloblastoma 5 | 1,524

Tissue

Blood and immune system 161 | 17,995
Digestive Tract 161 | 18,473
Female tissues 161 | 18,647
Skin and soft tissues 160 | 18,115
Urinary Tract 159 | 18,444
Liver and Pancreas 157 | 18,136
Nervous System 157 | 18,561
Respiratory system 157 | 17,484
Endocrine System 156 | 18,512
Cardiovascular System 155 | 17,958
Male tissues 152 | 17,969

Target Family

Non-IDG 137 | 11,971
Kinase 18 | 634
Enzyme 7 | 4,146
Transcription Factor 5 | 1,400
GPCR 2 | 406
Ion Channel 2 | 341
TF/Epigenetic 1 | 38

UniProt Keyword

Adaptive immunity 172 | 172
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
Natural killer cell receptor 2B4 CD244 Tbio Non-IDG -2.27438 190.1 418
Fibrinogen alpha chain FGA Tbio Non-IDG -2.84597 716.2 457
Complement component 1 Q subcomponent-binding protein, mitochondrial C1QBP Tbio Non-IDG -2.51978 332.6 298
Protein artemis DCLRE1C Tbio Non-IDG -1.63807 45.4 225
Endoplasmic reticulum aminopeptidase 1 ERAP1 Tchem Enzyme -2.22270 198.7 195
NKG2-D type II integral membrane protein KLRK1 Tbio Non-IDG -1.48442 31.1 337
Leukocyte immunoglobulin-like receptor subfamily B member 1 LILRB1 Tbio Non-IDG -2.16239 168.2 0
Immunoglobulin lambda variable 1-44 IGLV1-44 Tdark Non-IDG 0.00000 0
Immunoglobulin heavy variable 1-2 IGHV1-2 Tdark Non-IDG 0.00000 0