Development Level

Tbio 103 | 11,445
Tchem 32 | 1,598
Tdark 29 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, incomple... 6 | 499
preweaning lethality, complete... 5 | 979
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
abnormal embryo size 2 | 220
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating alanine ... 2 | 47
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
hyperactivity 2 | 148
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased circulating phosphat... 2 | 26
increased lean body mass 2 | 172
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal eye morphology 1 | 68
abnormal kidney morphology 1 | 65
abnormal lip morphology 1 | 2
abnormal lung morphology 1 | 26
abnormal maxilla morphology 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating creatine... 1 | 4
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
hydroencephaly 1 | 14
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating creatine... 1 | 5
increased circulating potassiu... 1 | 29
increased heart rate variabili... 1 | 7
increased or absent threshold ... 1 | 101
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74

Disease

Carcinoma 110 | 11,493
ovarian cancer 86 | 8,520
psoriasis 69 | 6,694
osteosarcoma 68 | 7,950
medulloblastoma, large-cell 54 | 6,241
glioblastoma 42 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 36 | 3,291
lung cancer 33 | 4,740
group 3 medulloblastoma 31 | 4,104
adult high grade glioma 30 | 3,801
atypical teratoid / rhabdoid tumor 30 | 5,112
Breast cancer 29 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 29 | 1,962
ependymoma 27 | 4,679
invasive ductal carcinoma 26 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
primitive neuroectodermal tumor 25 | 3,035
malignant mesothelioma 24 | 3,232
group 4 medulloblastoma 22 | 1,855
Astrocytoma, Pilocytic 20 | 3,081
Autosomal recessive predisposition 20 | 1,442
tuberculosis 20 | 2,010
astrocytic glioma 19 | 2,597
Cancer 18 | 2,499
Kidney cancer 18 | 2,613
Intellectual disability 17 | 1,016
Pick disease 17 | 1,894
diabetes mellitus 17 | 1,728
oligodendroglioma 17 | 2,850
Obesity 16 | 678
astrocytoma 16 | 1,146
ductal carcinoma in situ 16 | 1,745
lung adenocarcinoma 16 | 2,716
pancreatic cancer 16 | 2,398
subependymal giant cell astrocytoma 16 | 2,287
lung carcinoma 15 | 2,843
interstitial cystitis 14 | 2,312
ulcerative colitis 14 | 1,819
Muscle hypotonia 13 | 571
Dull intelligence 12 | 645
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Multiple myeloma 12 | 1,332
Poor school performance 12 | 645
acute quadriplegic myopathy 12 | 1,158
Rheumatoid arthritis 11 | 1,191
non-small cell lung cancer 11 | 2,890
spina bifida 11 | 1,074
Schizophrenia 10 | 1,160
Seizures 10 | 596
adrenocortical carcinoma 10 | 1,428
breast carcinoma 10 | 1,638
colon cancer 10 | 1,478
pituitary cancer 10 | 1,972
primary pancreatic ductal adenocarcinoma 10 | 1,109
Atopic dermatitis 9 | 952
Fatty liver disease 9 | 103
Liver Cirrhosis, Experimental 9 | 769
active Crohn's disease 9 | 922
Alzheimer's disease 8 | 658
Bipolar Disorder 8 | 666
Breast Neoplasms 8 | 445
Cognitive delay 8 | 608
Epilepsy 8 | 792
Global developmental delay 8 | 608
Mental and motor retardation 8 | 608
Small head 8 | 374
fibroadenoma 8 | 559
pediatric high grade glioma 8 | 1,064
Blepharoptosis 7 | 231
Byzanthine arch palate 7 | 194
Cataract 7 | 297
Failure to gain weight 7 | 365
Mammary Neoplasms 7 | 425
Pediatric failure to thrive 7 | 365
Strabismus 7 | 270
Waldenstrons macroglobulinemia 7 | 765
active ulcerative colitis 7 | 764
cystic fibrosis 7 | 1,696
Atrial Septal Defects 6 | 85
Carnitine palmitoyltransferase II deficiency 6 | 14
Feeding difficulties in infancy 6 | 175
Hepatomegaly 6 | 285
Low set ears 6 | 181
Melanoma 6 | 711
Neurodegenerative disease 6 | 414
Neuropathy 6 | 261
Prostatic Neoplasms 6 | 495
acute myeloid leukemia 6 | 783
aldosterone-producing adenoma 6 | 665
dermatomyositis 6 | 966
esophageal adenocarcinoma 6 | 737
juvenile dermatomyositis 6 | 1,187
mucosa-associated lymphoid tissue lymphoma 6 | 484
non primary Sjogren syndrome sicca 6 | 891
Ventricular Septal Defects 5 | 119
hepatocellular carcinoma 5 | 547
primary Sjogren syndrome 5 | 735

Tissue

Endocrine System 157 | 18,159
Digestive Tract 155 | 17,369
Female tissues 155 | 17,400
Skin and soft tissues 155 | 17,230
Male tissues 153 | 17,142
Blood and immune system 151 | 16,909
Liver and Pancreas 150 | 16,750
Nervous System 150 | 16,725
Urinary Tract 147 | 16,678
Respiratory system 145 | 16,393
Cardiovascular System 139 | 15,192

Target Family

Enzyme 138 | 4,145
Epigenetic 17 | 242
Non-IDG 7 | 12,091
TF/Epigenetic 2 | 38
Kinase 1 | 634

UniProt Keyword

Acyltransferase 165 | 165
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HRAS-like suppressor 2 HRASLS2 Tbio Non-IDG -0.19299 1.65 72
Protein-glutamine gamma-glutamyltransferase 6 TGM6 Tchem Enzyme -2.07471 113.3 54
Probable palmitoyltransferase ZDHHC8 ZDHHC8 Tbio Enzyme -1.30633 19.3 116
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial OXSM Tbio Enzyme -1.82909 65.1 127
Testis-specific chromodomain protein Y 1 CDY1 Tbio Epigenetic -1.26646 18.6 30
N-acetyltransferase ESCO1 ESCO1 Tbio Enzyme -1.65145 44.6 49
Glutaminyl-peptide cyclotransferase-like protein QPCTL Tchem Enzyme -1.04298 11.4 85
Protein-glutamine gamma-glutamyltransferase Z TGM7 Tdark Enzyme -0.49369 2.75 103
Palmitoyltransferase ZDHHC2 ZDHHC2 Tbio Enzyme -1.91418 79.6 82
Glycerol-3-phosphate acyltransferase 1, mitochondrial GPAM Tbio Enzyme -1.93041 83.4 177