Development Level

Tbio 89 | 10,625
Tchem 41 | 1,890
Tdark 38 | 7,003
Tclin 1 | 602

IMPC Term

preweaning lethality, incomple... 5 | 260
decreased circulating serum al... 3 | 79
preweaning lethality, complete... 3 | 633
abnormal rib morphology 2 | 28
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased circulating alanine ... 2 | 53
decreased circulating choleste... 2 | 85
decreased total body fat amoun... 2 | 186
increased bone mineral content 2 | 92
increased mean corpuscular hem... 2 | 93
persistence of hyaloid vascula... 2 | 22
abnormal behavior 1 | 226
abnormal body wall morphology 1 | 7
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal kidney morphology 1 | 30
abnormal lip morphology 1 | 2
abnormal lung morphology 1 | 15
abnormal maxilla morphology 1 | 16
abnormal retinal inner nuclear... 1 | 5
abnormal retinal pigmentation 1 | 61
abnormal seminal vesicle morph... 1 | 47
abnormal sleep behavior 1 | 63
abnormal thoracic vertebrae mo... 1 | 16
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 14
decreased B cell number 1 | 30
decreased Ly6C low monocyte nu... 1 | 23
decreased circulating LDL chol... 1 | 37
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating glucose ... 1 | 121
decreased circulating total pr... 1 | 41
decreased effector memory CD8-... 1 | 24
decreased fasted circulating g... 1 | 49
decreased lactate dehydrogenas... 1 | 14
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased thoracic vertebrae n... 1 | 7
decreased threshold for audito... 1 | 32
dilated heart left ventricle 1 | 10
enlarged heart 1 | 111
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
enlarged urinary bladder 1 | 4
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased KLRG1-positive NK ce... 1 | 9
increased NK cell number 1 | 19
increased bone mineral density 1 | 52
increased caudal vertebrae num... 1 | 8
increased circulating chloride... 1 | 43
increased circulating phosphat... 1 | 24
increased circulating potassiu... 1 | 31
increased effector memory CD4-... 1 | 15
increased fasted circulating g... 1 | 68
increased heart rate variabili... 1 | 4
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 25
increased plasma cell number 1 | 5
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
small seminal vesicle 1 | 6
thrombocytosis 1 | 23

Disease

ovarian cancer 86 | 8,484
psoriasis 73 | 6,685
osteosarcoma 69 | 7,933
medulloblastoma, large-cell 55 | 6,234
glioblastoma 42 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 36 | 3,289
lung cancer 32 | 4,466
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,956
pancreatic ductal adenocarcinoma liver metastasis 29 | 1,795
invasive ductal carcinoma 27 | 2,950
atypical teratoid / rhabdoid tumor 26 | 4,369
malignant mesothelioma 26 | 3,162
Breast cancer 25 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,988
primitive neuroectodermal tumor 25 | 3,031
group 4 medulloblastoma 23 | 1,875
pediatric high grade glioma 21 | 2,712
astrocytic glioma 20 | 2,241
pilocytic astrocytoma 20 | 3,086
ependymoma 19 | 2,514
Cancer 18 | 2,346
adult high grade glioma 18 | 2,148
group 3 medulloblastoma 18 | 2,254
ulcerative colitis 18 | 2,087
Pick disease 17 | 1,893
diabetes mellitus 17 | 1,663
ductal carcinoma in situ 17 | 1,745
lung adenocarcinoma 17 | 2,713
oligodendroglioma 17 | 2,849
subependymal giant cell astrocytoma 17 | 2,287
astrocytoma 16 | 1,493
pancreatic cancer 16 | 2,300
tuberculosis 16 | 1,557
interstitial cystitis 15 | 2,299
lung carcinoma 15 | 2,844
Obesity 14 | 616
medulloblastoma 14 | 1,524
Multiple myeloma 13 | 1,327
non-small cell lung cancer 13 | 2,798
acute quadriplegic myopathy 12 | 1,157
spina bifida 12 | 1,064
Carcinoma 11 | 2,147
breast carcinoma 11 | 1,614
primary pancreatic ductal adenocarcinoma 11 | 1,271
Rheumatoid Arthritis 10 | 1,160
active Crohn's disease 10 | 918
adrenocortical carcinoma 10 | 1,427
pituitary cancer 10 | 1,972
Atopic dermatitis 9 | 944
Fatty liver disease 9 | 84
Intellectual disability 9 | 573
colon cancer 9 | 1,475
posterior fossa group A ependymoma 9 | 1,511
Alzheimer's disease 8 | 644
Waldenstrons macroglobulinemia 8 | 765
cystic fibrosis 8 | 1,665
fibroadenoma 8 | 557
posterior fossa group B ependymoma 8 | 1,530
Mammary Neoplasms 7 | 410
atypical teratoid/rhabdoid tumor 7 | 1,095
Carnitine palmitoyltransferase II deficiency 6 | 16
Peripheral Neuropathy 6 | 303
Prostatic Neoplasms 6 | 471
acute myeloid leukemia 6 | 780
aldosterone-producing adenoma 6 | 664
dermatomyositis 6 | 933
esophageal adenocarcinoma 6 | 737
hepatocellular carcinoma 6 | 532
juvenile dermatomyositis 6 | 1,189
mucosa-associated lymphoid tissue lymphoma 6 | 480
non primary Sjogren syndrome sicca 6 | 840
primary Sjogren syndrome 6 | 789
sonic hedgehog group medulloblastoma 6 | 1,482
Atherosclerosis 5 | 275
Bladder Neoplasm 5 | 109
Huntington's disease 5 | 72
Lipid metabolism disorder 5 | 102
Neurodegenerative disease 5 | 383
gastric cancer 5 | 430
hereditary spastic paraplegia 5 | 313
nasopharyngeal carcinoma 5 | 1,056
Adenoid Cystic Carcinoma 4 | 99
Bipolar Disorder 4 | 266
Kidney disease 4 | 396
Melanoma 4 | 261
Metabolic syndrome X 4 | 155
Schizophrenia 4 | 501
beta-ketothiolase deficiency 4 | 13
gastric carcinoma 4 | 832
nephrosclerosis 4 | 329
tuberculosis and treatment for 3 months 4 | 327
Becker muscular dystrophy 3 | 187
Dermatitis, Allergic Contact 3 | 66
Down syndrome 3 | 548
IGA Glomerulonephritis 3 | 454
Multiple Sclerosis 3 | 498
Polycystic Ovary Syndrome 3 | 332
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
pancreatic carcinoma 3 | 567
progressive supranuclear palsy 3 | 674

Tissue

Digestive Tract 165 | 18,473
Endocrine System 165 | 18,512
Liver and Pancreas 165 | 18,136
Blood and immune system 164 | 17,995
Female tissues 164 | 18,647
Nervous System 164 | 18,561
Urinary Tract 164 | 18,444
Skin and soft tissues 163 | 18,115
Cardiovascular System 161 | 17,958
Male tissues 160 | 17,969
Respiratory system 159 | 17,484

Target Family

Enzyme 142 | 4,146
Epigenetic 18 | 242
Non-IDG 6 | 11,971
TF/Epigenetic 2 | 38
Kinase 1 | 634

UniProt Keyword

Acyltransferase 169 | 169
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
N-acetyltransferase 6 NAT6 Tbio Enzyme -0.82623 6.53 132
Glycine N-acyltransferase GLYAT Tbio Enzyme -1.86227 71.5 87
Gamma-glutamylaminecyclotransferase GGACT Tbio Enzyme -1.17488 15.0 60
Carnitine O-palmitoyltransferase 1, liver isoform CPT1A Tchem Enzyme -2.30451 203.2 252
Probable palmitoyltransferase ZDHHC14 ZDHHC14 Tdark Enzyme -0.71600 5.08 26
Gamma-glutamylcyclotransferase GGCT Tbio Enzyme -2.15784 135.0 114
Lysophospholipid acyltransferase 2 MBOAT2 Tbio Enzyme -1.34198 18.9 57
Putative diacylglycerol O-acyltransferase 2-like protein DGAT2L7P DGAT2L7P Tdark Enzyme 0.00000 0
Serine palmitoyltransferase 1 SPTLC1 Tchem Enzyme -2.15486 141.0 260
Serine palmitoyltransferase 2 SPTLC2 Tchem Enzyme -1.65355 46.3 182